Bridging the gaps in nanosafety for animal-free prediction of adverse outcomes

Información del proyecto

nanoPASS

Identificador del acuerdo de subvención: 101092741

DOI

10.3030/101092741

Fecha de la firma de la CE 24 Noviembre 2022

Fecha de inicio 1 Enero 2023

Fecha de finalización 31 Diciembre 2026

Financiado con arreglo a

• Digital, Industry and Space

Coste total

€ 3 073 736,25

Aportación de la UE

€ 3 073 736,25

Coordinado por

INSTITUT JOZEF STEFAN
Slovenia

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (2)

Submission of 1 manuscript on an AOP

The manuscript will be based on AOP 237, and it will be submitted to a suitable journal, e.g. ‘Environmental Toxicology and Chemistry’ or ‘Environmental and Molecular Mutagenesis.

Quality Management Plan

The QMP document will detail the roles of partners for the deliverables and milestones, and clear 6-month goals. It will be revised during the course of the project if needed.

Websites, patent fillings, videos etc. (1)

Project website

The one-stop-shop for project communication, both for external audiences and the consortium with a partner-only area. Will provide a repository (news, deliverables, events), and be the first interface for interested stakeholders with a contact form

Data Management Plan (1)

Management set-up

Set-up of the management structure and decision-making procedures, finalised at the kick-off meeting. Set-up of shared server for exchange of data and files, devised Data Management Plan (DMP) according to FAIR principles.

Publicaciones

Peer reviewed articles (15)

Carbonaceous particle exposure triggered accumulation of Osteopontin/SPP1+ macrophages contributes to emphysema development

Autores: Han, Lianyong; Haefner, Verena; Yildirim, Ali Önder; Adler, Heiko; Stoeger, Tobias
Publicado en: MedComm, 2025, ISSN 2688-2663
Editor: Wiley
DOI: 10.1002/MCO2.70061

Acute, controlled inhalation of thin graphene oxide nanosheets in humans with null cardiorespiratory effects.

Autores: Ulla Vogel
Publicado en: Nature Nanotechnology, Edición 19, 2024, ISSN 1748-3387
Editor: Springer Nature
DOI: 10.1038/s41565-024-01639-9

Setting off on the right path: make your research regulatory relevant

Autores: Anna Pohl; Elise Morel; Elise Morel; Eric A. J. Bleeker; Sean Kelly; Rachel Smith; Claus Svendsen; Thomas A. J. Kuhlbusch; Thomas A. J. Kuhlbusch; Thomas A. J. Kuhlbusch; Elisabeth Heunisch
Publicado en: Frontiers in Research Metrics and Analytics, 2025, ISSN 2504-0537
Editor: Frontiers Media
DOI: 10.3389/FRMA.2025.1561964

Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -containing plaques and neurite shortening in vitro

Autores: A Sebastijanović, L M Azzurra Camassa, V Malmborg, S Kralj, J Pagels, U Vogel, S Zienolddiny-Narui, I Urbančič, T Koklič and J Štrancar
Publicado en: Nanotoxicology, 2024, ISSN 1743-5390
Editor: Informa Healthcare
DOI: 10.1080/17435390.2024.2362367

Computational modelling of bionano interface

Autores: V. Lobaskin, J. Subbotina, I. Rouse
Publicado en: EPL, Edición 143, 2023, ISSN 1286-4854
Editor: IOP Science
DOI: 10.1209/0295-5075/acf33f

Nanoparticle-Exposure-Triggered Virus Reactivation Induces Lung Emphysema in Mice

Autores: Han L, Haefner V, Yu Y, Han B, Ren H, Irmler M, Beckers J, Liu Q, Feuchtinger A, Yildirim AO, Adler H, Stoeger T
Publicado en: ACS Nano, Edición 17/21, 2023, ISSN 1936-086X
Editor: American Chemical Society
DOI: 10.1021/acsnano.3c04111

An elevated rate of whole-genome duplications associated with carcinogen exposure in Black cancer patients

Autores: Leanne M. Brown; Ryan A. Hagenson; Tilen Koklič; Iztok Urbančič; Janez Strancar; Jason M. Sheltzer
Publicado en: Crossref, 2023, ISSN 3067-2007
Editor: medRxiv
DOI: 10.1101/2023.11.10.23298349

Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: Implications for Nanotoxicological Hazard Assessment

Autores: Peng Lei; Fikirte Debebe Zegeye; Mayes Alswady-Hoff; Chiara Marcolungo; Pernille Høgh Danielsen; Anne Mette Madsen; Håkan Wallin; Ulla Vogel; Shan Zienolddiny-Narui; Johanna Samulin Erdem
Publicado en: Nanomaterials, 2025, ISSN 2079-4991
Editor: MDPI
DOI: 10.3390/NANO15241871

NPCoronaPredict: A Computational Pipeline for the Prediction of the Nanoparticle–Biomolecule Corona

Autores: Ian Rouse; David Power; Julia Subbotina; Vladimir Lobaskin
Publicado en: Journal of Chemical Information and Modeling, 2024, ISSN 1549-960X
Editor: American Chemical Society
DOI: 10.48550/ARXIV.2403.07819

<i>UANanoDock</i>: A Web-Based <i>UnitedAtom</i> Multiscale Nanodocking Tool for Predicting Protein Adsorption onto Nanoparticles

Autores: Julia Subbotina; Panagiotis D. Kolokathis; Andreas Tsoumanis; Nikolaos K. Sidiropoulos; Ian Rouse; Iseult Lynch; Vladimir Lobaskin; Antreas Afantitis
Publicado en: Journal of Chemical Information and Modeling, 2025, ISSN 1549-960X
Editor: American Chemical Society
DOI: 10.1021/ACS.JCIM.4C02292

Metadata stewardship in nanosafety research: learning from the past, preparing for an “on-the-fly” FAIR future

Autores: Thomas E. Exner; Anastasios G. Papadiamantis; Anastasios G. Papadiamantis; Georgia Melagraki; Jaleesia D. Amos; Nathan Bossa; Nathan Bossa; Georgios P. Gakis; Costas A. Charitidis; Geert Cornelis; Anna L. Costa; Philip Doganis; Lucian Farcal; Steffi Friedrichs; Irini Furxhi; Frederick C. Klaessig; Vladimir Lobaskin; Dieter Maier; John Rumble; John Rumble; Haralambos Sarimveis; Blanca Suarez-Merino; Socorro Vázquez; Mark R. Wiesner; Antreas Afantitis; Antreas Afantitis; Iseult Lynch; Iseult Lynch
Publicado en: Frontiers in Physics, 2023, ISSN 2296-424X
Editor: Frontiers Media
DOI: 10.5281/ZENODO.8326590

Nature Communications

Autores: Leanne M. Brown; Ryan A. Hagenson; Tilen Koklič; Iztok Urbančič; Lu Qiao; Janez Strancar; Jason M. Sheltzer
Publicado en: Nature Communications, 2024, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/S41467-024-52554-5

Comparison of Lung Inflammatory and Transcriptional Responses in Mice and Rats Following Pulmonary Exposure to a Fiber Paradigm-Compatible and Non-Compatible MWCNT

Autores: Laura Aliisa Saarimäki; Pernille Høgh Danielsen; Kristina Bram Knudsen; Sarah Søs Poulsen; Sabina Halappanavar; Henrik Wolff; Pia Anneli Sofia Kinaret; Dario Greco; Ulla Vogel
Publicado en: Nanomaterials, 2025, ISSN 2079-4991
Editor: MDPI
DOI: 10.3390/NANO15171364

Beilstein Journal of Nanotechnology

Autores: Parinaz Mosaddeghi Amini; Ian Rouse; Julia Subbotina; Vladimir Lobaskin
Publicado en: Beilstein Journal of Nanotechnology, 2023, ISSN 2190-4286
Editor: Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI: 10.3762/BJNANO.15.21

The eATP/P2×7R Axis Drives Quantum Dot‐Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation

Autores: Chenxi Li; Qiongliang Liu; Lianyong Han; Haiyun Zhang; Roland Immler; Birgit Rathkolb; Judith Secklehner; Martin Hrabe de Angelis; Ali Önder Yildirim; Dagmar Zeuschner; Annette Nicke; Leo M. Carlin; Markus Sperandio; Tobias Stoeger; Markus Rehberg
Publicado en: Advanced Science, 2024, ISSN 2198-3844
Editor: Wiley-VCH GmbH
DOI: 10.1002/ADVS.202404661