Bridging the gaps in nanosafety for animal-free prediction of adverse outcomes

Informazioni relative al progetto

nanoPASS

ID dell’accordo di sovvenzione: 101092741

DOI

10.3030/101092741

Data della firma CE 24 Novembre 2022

Data di avvio 1 Gennaio 2023

Data di completamento 31 Dicembre 2026

Finanziato da

• Digital, Industry and Space

Costo totale

€ 3 073 736,25

Contributo UE

€ 3 073 736,25

Coordinato da

INSTITUT JOZEF STEFAN
Slovenia

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (2)

Submission of 1 manuscript on an AOP

The manuscript will be based on AOP 237, and it will be submitted to a suitable journal, e.g. ‘Environmental Toxicology and Chemistry’ or ‘Environmental and Molecular Mutagenesis.

Quality Management Plan

The QMP document will detail the roles of partners for the deliverables and milestones, and clear 6-month goals. It will be revised during the course of the project if needed.

Websites, patent fillings, videos etc. (1)

Project website

The one-stop-shop for project communication, both for external audiences and the consortium with a partner-only area. Will provide a repository (news, deliverables, events), and be the first interface for interested stakeholders with a contact form

Data Management Plan (1)

Management set-up

Set-up of the management structure and decision-making procedures, finalised at the kick-off meeting. Set-up of shared server for exchange of data and files, devised Data Management Plan (DMP) according to FAIR principles.

Pubblicazioni

Peer reviewed articles (15)

Carbonaceous particle exposure triggered accumulation of Osteopontin/SPP1+ macrophages contributes to emphysema development

Autori: Han, Lianyong; Haefner, Verena; Yildirim, Ali Önder; Adler, Heiko; Stoeger, Tobias
Pubblicato in: MedComm, 2025, ISSN 2688-2663
Editore: Wiley
DOI: 10.1002/MCO2.70061

Acute, controlled inhalation of thin graphene oxide nanosheets in humans with null cardiorespiratory effects.

Autori: Ulla Vogel
Pubblicato in: Nature Nanotechnology, Numero 19, 2024, ISSN 1748-3387
Editore: Springer Nature
DOI: 10.1038/s41565-024-01639-9

Setting off on the right path: make your research regulatory relevant

Autori: Anna Pohl; Elise Morel; Elise Morel; Eric A. J. Bleeker; Sean Kelly; Rachel Smith; Claus Svendsen; Thomas A. J. Kuhlbusch; Thomas A. J. Kuhlbusch; Thomas A. J. Kuhlbusch; Elisabeth Heunisch
Pubblicato in: Frontiers in Research Metrics and Analytics, 2025, ISSN 2504-0537
Editore: Frontiers Media
DOI: 10.3389/FRMA.2025.1561964

Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -containing plaques and neurite shortening in vitro

Autori: A Sebastijanović, L M Azzurra Camassa, V Malmborg, S Kralj, J Pagels, U Vogel, S Zienolddiny-Narui, I Urbančič, T Koklič and J Štrancar
Pubblicato in: Nanotoxicology, 2024, ISSN 1743-5390
Editore: Informa Healthcare
DOI: 10.1080/17435390.2024.2362367

Computational modelling of bionano interface

Autori: V. Lobaskin, J. Subbotina, I. Rouse
Pubblicato in: EPL, Numero 143, 2023, ISSN 1286-4854
Editore: IOP Science
DOI: 10.1209/0295-5075/acf33f

Nanoparticle-Exposure-Triggered Virus Reactivation Induces Lung Emphysema in Mice

Autori: Han L, Haefner V, Yu Y, Han B, Ren H, Irmler M, Beckers J, Liu Q, Feuchtinger A, Yildirim AO, Adler H, Stoeger T
Pubblicato in: ACS Nano, Numero 17/21, 2023, ISSN 1936-086X
Editore: American Chemical Society
DOI: 10.1021/acsnano.3c04111

An elevated rate of whole-genome duplications associated with carcinogen exposure in Black cancer patients

Autori: Leanne M. Brown; Ryan A. Hagenson; Tilen Koklič; Iztok Urbančič; Janez Strancar; Jason M. Sheltzer
Pubblicato in: Crossref, 2023, ISSN 3067-2007
Editore: medRxiv
DOI: 10.1101/2023.11.10.23298349

Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: Implications for Nanotoxicological Hazard Assessment

Autori: Peng Lei; Fikirte Debebe Zegeye; Mayes Alswady-Hoff; Chiara Marcolungo; Pernille Høgh Danielsen; Anne Mette Madsen; Håkan Wallin; Ulla Vogel; Shan Zienolddiny-Narui; Johanna Samulin Erdem
Pubblicato in: Nanomaterials, 2025, ISSN 2079-4991
Editore: MDPI
DOI: 10.3390/NANO15241871

NPCoronaPredict: A Computational Pipeline for the Prediction of the Nanoparticle–Biomolecule Corona

Autori: Ian Rouse; David Power; Julia Subbotina; Vladimir Lobaskin
Pubblicato in: Journal of Chemical Information and Modeling, 2024, ISSN 1549-960X
Editore: American Chemical Society
DOI: 10.48550/ARXIV.2403.07819

<i>UANanoDock</i>: A Web-Based <i>UnitedAtom</i> Multiscale Nanodocking Tool for Predicting Protein Adsorption onto Nanoparticles

Autori: Julia Subbotina; Panagiotis D. Kolokathis; Andreas Tsoumanis; Nikolaos K. Sidiropoulos; Ian Rouse; Iseult Lynch; Vladimir Lobaskin; Antreas Afantitis
Pubblicato in: Journal of Chemical Information and Modeling, 2025, ISSN 1549-960X
Editore: American Chemical Society
DOI: 10.1021/ACS.JCIM.4C02292

Metadata stewardship in nanosafety research: learning from the past, preparing for an “on-the-fly” FAIR future

Autori: Thomas E. Exner; Anastasios G. Papadiamantis; Anastasios G. Papadiamantis; Georgia Melagraki; Jaleesia D. Amos; Nathan Bossa; Nathan Bossa; Georgios P. Gakis; Costas A. Charitidis; Geert Cornelis; Anna L. Costa; Philip Doganis; Lucian Farcal; Steffi Friedrichs; Irini Furxhi; Frederick C. Klaessig; Vladimir Lobaskin; Dieter Maier; John Rumble; John Rumble; Haralambos Sarimveis; Blanca Suarez-Merino; Socorro Vázquez; Mark R. Wiesner; Antreas Afantitis; Antreas Afantitis; Iseult Lynch; Iseult Lynch
Pubblicato in: Frontiers in Physics, 2023, ISSN 2296-424X
Editore: Frontiers Media
DOI: 10.5281/ZENODO.8326590

Nature Communications

Autori: Leanne M. Brown; Ryan A. Hagenson; Tilen Koklič; Iztok Urbančič; Lu Qiao; Janez Strancar; Jason M. Sheltzer
Pubblicato in: Nature Communications, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/S41467-024-52554-5

Comparison of Lung Inflammatory and Transcriptional Responses in Mice and Rats Following Pulmonary Exposure to a Fiber Paradigm-Compatible and Non-Compatible MWCNT

Autori: Laura Aliisa Saarimäki; Pernille Høgh Danielsen; Kristina Bram Knudsen; Sarah Søs Poulsen; Sabina Halappanavar; Henrik Wolff; Pia Anneli Sofia Kinaret; Dario Greco; Ulla Vogel
Pubblicato in: Nanomaterials, 2025, ISSN 2079-4991
Editore: MDPI
DOI: 10.3390/NANO15171364

Beilstein Journal of Nanotechnology

Autori: Parinaz Mosaddeghi Amini; Ian Rouse; Julia Subbotina; Vladimir Lobaskin
Pubblicato in: Beilstein Journal of Nanotechnology, 2023, ISSN 2190-4286
Editore: Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI: 10.3762/BJNANO.15.21

The eATP/P2×7R Axis Drives Quantum Dot‐Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation

Autori: Chenxi Li; Qiongliang Liu; Lianyong Han; Haiyun Zhang; Roland Immler; Birgit Rathkolb; Judith Secklehner; Martin Hrabe de Angelis; Ali Önder Yildirim; Dagmar Zeuschner; Annette Nicke; Leo M. Carlin; Markus Sperandio; Tobias Stoeger; Markus Rehberg
Pubblicato in: Advanced Science, 2024, ISSN 2198-3844
Editore: Wiley-VCH GmbH
DOI: 10.1002/ADVS.202404661