Bridging the gaps in nanosafety for animal-free prediction of adverse outcomes

Informations projet

nanoPASS

N° de convention de subvention: 101092741

DOI

10.3030/101092741

Date de signature de la CE 24 Novembre 2022

Date de début 1 Janvier 2023

Date de fin 31 Decembre 2026

Financé au titre de

• Digital, Industry and Space

Coût total

€ 3 073 736,25

Contribution de l’UE

€ 3 073 736,25

Coordonné par

INSTITUT JOZEF STEFAN
Slovenia

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (2)

Submission of 1 manuscript on an AOP

The manuscript will be based on AOP 237, and it will be submitted to a suitable journal, e.g. ‘Environmental Toxicology and Chemistry’ or ‘Environmental and Molecular Mutagenesis.

Quality Management Plan

The QMP document will detail the roles of partners for the deliverables and milestones, and clear 6-month goals. It will be revised during the course of the project if needed.

Websites, patent fillings, videos etc. (1)

Project website

The one-stop-shop for project communication, both for external audiences and the consortium with a partner-only area. Will provide a repository (news, deliverables, events), and be the first interface for interested stakeholders with a contact form

Data Management Plan (1)

Management set-up

Set-up of the management structure and decision-making procedures, finalised at the kick-off meeting. Set-up of shared server for exchange of data and files, devised Data Management Plan (DMP) according to FAIR principles.

Publications

Peer reviewed articles (15)

Carbonaceous particle exposure triggered accumulation of Osteopontin/SPP1+ macrophages contributes to emphysema development

Auteurs: Han, Lianyong; Haefner, Verena; Yildirim, Ali Önder; Adler, Heiko; Stoeger, Tobias
Publié dans: MedComm, 2025, ISSN 2688-2663
Éditeur: Wiley
DOI: 10.1002/MCO2.70061

Acute, controlled inhalation of thin graphene oxide nanosheets in humans with null cardiorespiratory effects.

Auteurs: Ulla Vogel
Publié dans: Nature Nanotechnology, Numéro 19, 2024, ISSN 1748-3387
Éditeur: Springer Nature
DOI: 10.1038/s41565-024-01639-9

Setting off on the right path: make your research regulatory relevant

Auteurs: Anna Pohl; Elise Morel; Elise Morel; Eric A. J. Bleeker; Sean Kelly; Rachel Smith; Claus Svendsen; Thomas A. J. Kuhlbusch; Thomas A. J. Kuhlbusch; Thomas A. J. Kuhlbusch; Elisabeth Heunisch
Publié dans: Frontiers in Research Metrics and Analytics, 2025, ISSN 2504-0537
Éditeur: Frontiers Media
DOI: 10.3389/FRMA.2025.1561964

Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -containing plaques and neurite shortening in vitro

Auteurs: A Sebastijanović, L M Azzurra Camassa, V Malmborg, S Kralj, J Pagels, U Vogel, S Zienolddiny-Narui, I Urbančič, T Koklič and J Štrancar
Publié dans: Nanotoxicology, 2024, ISSN 1743-5390
Éditeur: Informa Healthcare
DOI: 10.1080/17435390.2024.2362367

Computational modelling of bionano interface

Auteurs: V. Lobaskin, J. Subbotina, I. Rouse
Publié dans: EPL, Numéro 143, 2023, ISSN 1286-4854
Éditeur: IOP Science
DOI: 10.1209/0295-5075/acf33f

Nanoparticle-Exposure-Triggered Virus Reactivation Induces Lung Emphysema in Mice

Auteurs: Han L, Haefner V, Yu Y, Han B, Ren H, Irmler M, Beckers J, Liu Q, Feuchtinger A, Yildirim AO, Adler H, Stoeger T
Publié dans: ACS Nano, Numéro 17/21, 2023, ISSN 1936-086X
Éditeur: American Chemical Society
DOI: 10.1021/acsnano.3c04111

An elevated rate of whole-genome duplications associated with carcinogen exposure in Black cancer patients

Auteurs: Leanne M. Brown; Ryan A. Hagenson; Tilen Koklič; Iztok Urbančič; Janez Strancar; Jason M. Sheltzer
Publié dans: Crossref, 2023, ISSN 3067-2007
Éditeur: medRxiv
DOI: 10.1101/2023.11.10.23298349

Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: Implications for Nanotoxicological Hazard Assessment

Auteurs: Peng Lei; Fikirte Debebe Zegeye; Mayes Alswady-Hoff; Chiara Marcolungo; Pernille Høgh Danielsen; Anne Mette Madsen; Håkan Wallin; Ulla Vogel; Shan Zienolddiny-Narui; Johanna Samulin Erdem
Publié dans: Nanomaterials, 2025, ISSN 2079-4991
Éditeur: MDPI
DOI: 10.3390/NANO15241871

NPCoronaPredict: A Computational Pipeline for the Prediction of the Nanoparticle–Biomolecule Corona

Auteurs: Ian Rouse; David Power; Julia Subbotina; Vladimir Lobaskin
Publié dans: Journal of Chemical Information and Modeling, 2024, ISSN 1549-960X
Éditeur: American Chemical Society
DOI: 10.48550/ARXIV.2403.07819

<i>UANanoDock</i>: A Web-Based <i>UnitedAtom</i> Multiscale Nanodocking Tool for Predicting Protein Adsorption onto Nanoparticles

Auteurs: Julia Subbotina; Panagiotis D. Kolokathis; Andreas Tsoumanis; Nikolaos K. Sidiropoulos; Ian Rouse; Iseult Lynch; Vladimir Lobaskin; Antreas Afantitis
Publié dans: Journal of Chemical Information and Modeling, 2025, ISSN 1549-960X
Éditeur: American Chemical Society
DOI: 10.1021/ACS.JCIM.4C02292

Metadata stewardship in nanosafety research: learning from the past, preparing for an “on-the-fly” FAIR future

Auteurs: Thomas E. Exner; Anastasios G. Papadiamantis; Anastasios G. Papadiamantis; Georgia Melagraki; Jaleesia D. Amos; Nathan Bossa; Nathan Bossa; Georgios P. Gakis; Costas A. Charitidis; Geert Cornelis; Anna L. Costa; Philip Doganis; Lucian Farcal; Steffi Friedrichs; Irini Furxhi; Frederick C. Klaessig; Vladimir Lobaskin; Dieter Maier; John Rumble; John Rumble; Haralambos Sarimveis; Blanca Suarez-Merino; Socorro Vázquez; Mark R. Wiesner; Antreas Afantitis; Antreas Afantitis; Iseult Lynch; Iseult Lynch
Publié dans: Frontiers in Physics, 2023, ISSN 2296-424X
Éditeur: Frontiers Media
DOI: 10.5281/ZENODO.8326590

Nature Communications

Auteurs: Leanne M. Brown; Ryan A. Hagenson; Tilen Koklič; Iztok Urbančič; Lu Qiao; Janez Strancar; Jason M. Sheltzer
Publié dans: Nature Communications, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/S41467-024-52554-5

Comparison of Lung Inflammatory and Transcriptional Responses in Mice and Rats Following Pulmonary Exposure to a Fiber Paradigm-Compatible and Non-Compatible MWCNT

Auteurs: Laura Aliisa Saarimäki; Pernille Høgh Danielsen; Kristina Bram Knudsen; Sarah Søs Poulsen; Sabina Halappanavar; Henrik Wolff; Pia Anneli Sofia Kinaret; Dario Greco; Ulla Vogel
Publié dans: Nanomaterials, 2025, ISSN 2079-4991
Éditeur: MDPI
DOI: 10.3390/NANO15171364

Beilstein Journal of Nanotechnology

Auteurs: Parinaz Mosaddeghi Amini; Ian Rouse; Julia Subbotina; Vladimir Lobaskin
Publié dans: Beilstein Journal of Nanotechnology, 2023, ISSN 2190-4286
Éditeur: Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI: 10.3762/BJNANO.15.21

The eATP/P2×7R Axis Drives Quantum Dot‐Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation

Auteurs: Chenxi Li; Qiongliang Liu; Lianyong Han; Haiyun Zhang; Roland Immler; Birgit Rathkolb; Judith Secklehner; Martin Hrabe de Angelis; Ali Önder Yildirim; Dagmar Zeuschner; Annette Nicke; Leo M. Carlin; Markus Sperandio; Tobias Stoeger; Markus Rehberg
Publié dans: Advanced Science, 2024, ISSN 2198-3844
Éditeur: Wiley-VCH GmbH
DOI: 10.1002/ADVS.202404661