Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis
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Autori:
Chao Zheng, Bastien Hervé, Mandy Meijer, Leslie Ann Rubio Rodríguez-Kirby, André Ortlieb Guerreiro Cacais, Petra Kukanja, Mukund Kabbe, Tony Jimenez-Beristain, Tomas Olsson, Eneritz Agirre, Gonçalo Castelo-Branco
Pubblicato in:
Nature Neuroscience, Numero 28, 2025, ISSN 1097-6256
Editore:
Springer Science and Business Media LLC
DOI:
10.1038/S41593-025-02100-3
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
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Autori:
Olivia G. Thomas, Urszula Rykaczewska, Marina Galešić, Rianne T.M. van der Burgt, Nils Hallén, Filippo Ferro, Mattias Bronge, Zoe Marti, Yue Li, Alexandra Hill Riqué, Jianing Lin, Aleksa Krstic, Alicja Gromadzka, András Levente Szonder, Chiara Sorini, María Reina-Campos, Ting Sun, Leslie A. Rubio Rodríguez-Kirby, Özge Dumral, Rasmus Berglund, Majid Pahlevan Kakhki, Milena Z. Adzemovic, Manuel Zeitelhofer, Birce Akpinar, Katarina Tengvall, Ola B. Nilsson, Erik Holmgren, Chiara Starvaggi Cucuzza, Klara Asplund Högelin, Guro Gafvelin, Katharina Fink, Gonçalo Castelo-Branco, Maria Needhamsen, Mohsen Khademi, Fredrik Piehl, Torbjörn Gräslund, Lars Alfredsson, Harald Lund, Per Uhlén, Ingrid Kockum, Roland Martin, Maja Jagodic, Hans Grönlund, André Ortlieb Guerreiro-Cacais, Tomas Olsson
Pubblicato in:
Cell, Numero 189, 2026, ISSN 0092-8674
Editore:
Elsevier BV
DOI:
10.1016/J.CELL.2025.12.032
Disease-associated oligodendroglia: a putative nexus in neurodegeneration
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Autori:
Gonçalo Castelo-Branco, Petra Kukanja, André O. Guerreiro-Cacais, Leslie A. Rubio Rodríguez-Kirby
Pubblicato in:
Trends in Immunology, Numero 45, 2024, ISSN 1471-4906
Editore:
Elsevier BV
DOI:
10.1016/J.IT.2024.08.003
Spatial dynamics of brain development and neuroinflammation
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Autori:
Di Zhang, Leslie A. Rubio Rodríguez-Kirby, Yingxin Lin, Wenqi Wang, Mengyi Song, Li Wang, Lijun Wang, Shigeaki Kanatani, Tony Jimenez-Beristain, Yonglong Dang, Mei Zhong, Petra Kukanja, Shuozhen Bao, Shaohui Wang, Xinyi Lisa Chen, Fu Gao, Dejiang Wang, Hang Xu, Cong Ma, Xing Lou, Yang Liu, Jinmiao Chen, Nenad Sestan, Per Uhlén, Arnold Kriegstein, Hongyu Zhao, Gonçalo Castelo-Branco, Rong Fan
Pubblicato in:
Nature, Numero 647, 2025, ISSN 0028-0836
Editore:
Springer Science and Business Media LLC
DOI:
10.1038/S41586-025-09663-Y
