Understanding Lung Cancer related risk factors and their Impact

Información del proyecto

LUCIA

Identificador del acuerdo de subvención: 101096473

DOI

10.3030/101096473

Fecha de la firma de la CE 5 Diciembre 2022

Fecha de inicio 1 Enero 2023

Fecha de finalización 31 Diciembre 2026

Financiado con arreglo a

• Health

Coste total

€ 13 516 869,00

Aportación de la UE

€ 13 516 869,00

Coordinado por

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (10)

Clinical protocol and regulatory authorization report: General population Screening

Clinical protocol for the cohort study in the general population screening and the regulatory authorizations will be collected.

Common work plan for scientific collaboration under the ‘Understanding’ cluster
Communication, Dissemination and Exploitation Plan

Outlines the key activities, identifies stakeholders, and provides timelines, and indicators, including project website release.

Policy brief formulating recommendations based on the research and innovation strand of the ‘Understanding’ annual cluster meeting-M12
Data Management Plan-6M

Document describing the principles and initial plans of the project for data management (M06).The preparation of the Data Management Plan will include a common chapter on the ‘Understanding’ cluster. The aim of the chapter is to address commonalities in data standards, data validation, data protection and fostering data exchange, in particular when it comes to sharing project data with a future federated UNCAN.eu data platform. Therefore, interactions are envisaged with the 4.UNCAN.eu (http://uncaninitiative.eu/) coordination and support action which is preparing a blueprint for UNCAN.eu.

Conclusions of common annual meeting of the ‘Understanding’ cluster-M12
Policy brief formulating recommendations based on the research and innovation strand of the ‘Understanding’ annual cluster meeting-M24
Conclusions of common annual meeting of the ‘Understanding’ cluster-M24
LUCIA Management Report-9M

LUCIA Management Report- Initial report on M9 describing IPR, impact, and technology steering aspects of the project.

Clinical protocol and regulatory authorization report: Precision Screening and Diagnosis

The design of clinical protocol established by the clinical partners for the precision screening and diagnosis phases and the regulatory authorizations will be collected.

Websites, patent fillings, videos etc. (2)

Project website maintenance
Common video and/or a common cluster brochure

Common video and/or a common cluster brochure (cluster 'understanding')

Publicaciones

Peer reviewed articles (24)

Short-term effects of electronic cigarette smoking on cardiorespiratory parameters, volatile organic compounds and inflammatory markers

Autores: Suha Rizik; Ronen Bar-Yoseph; Moneera Hanna; Fahed Hakim; Yoav Broza; Amir Sader; Yazeed Toukan; Hossam Haick; Lea Bentur; Michal Gur
Publicado en: ERJ Open Research, Edición 01096-2024, 2025, ISSN 2312-0541
Editor: European Respiratory Society (ERS)
DOI: 10.1183/23120541.01096-2024

Scientific Reports

Autores: Jacob Levman; Yoav Y. Broza
Publicado en: Scientific Reports, Edición 9436, 2025, ISSN 2045-2322
Editor: Springer Nature
DOI: 10.1038/S41598-025-89820-5

Variable efficiency of nonsense-mediated mRNA decay across human tissues, tumors and individuals

Autores: Guillermo Palou-Márquez; Fran Supek
Publicado en: Genome Biology, Edición 316, 2024, ISSN 1474-760X
Editor: Springer Nature
DOI: 10.1186/S13059-025-03727-Y

Nature Communications

Autores: Ahmed Khalil; Fran Supek
Publicado en: Nature Communications, Edición 16 (42209), 2025, ISSN 2041-1723
Editor: Nature Portfolio
DOI: 10.1038/S41467-025-59397-8

Genome-scale quantification and prediction of pathogenic stop codon readthrough by small molecules

Autores: Ignasi Toledano; Fran Supek; Ben Lehner
Publicado en: Nature Genetics, 2024, ISSN 1546-1718
Editor: Nature Portfolio
DOI: 10.1101/2023.08.07.552350

Next‐Gen Wearables Unlocking Chemical Secrets

Autores: Hossam Haick
Publicado en: Advanced Sensor Research, Edición 3, 2024, ISSN 2751-1219
Editor: Wiley
DOI: 10.1002/adsr.202300203

Genome Medicine

Autores: Ferrer-Torres, Patricia; Galvan-Femenia, Ivan; Supek, Fran
Publicado en: Genome Medicine, Edición 76, 2025, ISSN 1756-994X
Editor: BioMed Central
DOI: 10.1186/S13073-025-01497-7

Computers in Biology and Medicine

Autores: B. Farina, R. Carbajo Benito, D. Montalvo-García, D. Bermejo-Peláez, L. Seijo Maceiras, M.J. Ledesma-Carbayo
Publicado en: Computers in Biology and Medicine, Edición 196, 2025, ISSN 0010-4825
Editor: Pergamon Press Ltd.
DOI: 10.1016/J.COMPBIOMED.2025.110813

Risk-Adapted Lung Cancer Screening Starting Ages for Former Smokers

Autores: Clara Frick, Lára R. Hallsson, Uwe Siebert, Megha Bhardwaj, Ben Schöttker, Hermann Brenner
Publicado en: JAMA Network Open, Edición 8, 2025, ISSN 2574-3805
Editor: American Medical Association (AMA)
DOI: 10.1001/JAMANETWORKOPEN.2025.51281

Nature Communications

Autores: Jian Yang; Xia Gong; Ying Zheng; Hong Duan; Shuijin Chen; Tong Wu; Changqing Yi; Lelun Jiang; Hossam Haick
Publicado en: Nature Communications, Edición 16 (6260), 2025, ISSN 2041-1723
Editor: Nature Portfolio
DOI: 10.1038/S41467-025-61549-9

Long Term Evaluation of Quantitative Cumulative Irradiation in Patients Suffering from ILDs

Autores: Berg, Julien; Frix, Anne-Noëlle; Henket, Monique; GESTER, Fanny; Winandy, Marie-Laurence; CANIVET, Perrine; Njock, Makon-Sébastien; THYS, Marie; DESIR, Colin; Meunier, Paul; Louis, Renaud; Malchair,
Publicado en: Diagnostics, Edición 14(19), 2024, ISSN 2075-4418
Editor: MDPI
DOI: 10.3390/DIAGNOSTICS14192136

Nature Communications

Autores: Elizaveta Besedina; Fran Supek
Publicado en: Nature Communications, Edición 15 (6139), 2024, ISSN 2041-1723
Editor: Nature Portfolio
DOI: 10.1038/S41467-024-50552-1

Spin-induced nanomaterials for detection of chiral volatile organic compounds

Autores: Arnab Maity, Hossam Haick
Publicado en: Applied Physics Reviews, Edición 10, 2023, ISSN 1931-9401
Editor: AIP Publishing
DOI: 10.1063/5.0146656

Self‐Sustaining Triboelectric Nanosensors for Real‐Time Urine Analysis in Smart Toilets

Autores: Indrajit Mondal, Elias Mansour, Youbin Zheng, Ritu Gupta, Hossam Haick
Publicado en: Small, 2024, ISSN 1613-6810
Editor: Wiley
DOI: 10.1002/smll.202403385

Protocol to fabricate wearable stretchable microneedle-based sensors

Autores: Rawan Omar, Youbin Zheng, Hossam Haick
Publicado en: STAR Protocols, 2023, ISSN 2666-1667
Editor: Cell Press
DOI: 10.1016/j.xpro.2023.102751

Spin‐Controlled Helical Quantum Sieve Chiral Spectrometer

Autores: Arnab Maity, Yael Hershkovitz‐Pollak, Ritu Gupta, Weiwei Wu, Hossam Haick
Publicado en: Advanced Materials, Edición 35, 2023, ISSN 0935-9648
Editor: Wiley
DOI: 10.1002/adma.202209125

Advances in volatile organic compounds detection: From fundamental research to real-world applications

Autores: Haick, H.
Publicado en: Applied Physics Review, Edición 11, 2024, ISSN 1931-9401
Editor: AIP Publishing
DOI: 10.1063/5.0230205

Liquid Biopsy-Based Volatile Organic Compounds from Blood and Urine and Their Combined Data Sets for Highly Accurate Detection of Cancer

Autores: Reef Einoch Amor, Jeremy Levy, Yoav Y. Broza, Reinis Vangravs, Shelley Rapoport, Min Zhang, Weiwei Wu, Marcis Leja, Joachim A. Behar, Hossam Haick
Publicado en: ACS Sensors, Edición 8, 2023, ISSN 2379-3694
Editor: American Chemical Society (ACS)
DOI: 10.1021/acssensors.2c02422

Chemical Tomography of Cancer Organoids and Cyto‐Proteo‐Genomic Development Stages Through Chemical Communication Signals

Autores: Arnab Maity; Vivian Darsa Maidantchik; Keren Weidenfeld; Sarit Larisch; Dalit Barkan; Hossam Haick
Publicado en: Advanced Materials, Edición 2413017, 2025, ISSN 1521-4095
Editor: Wiley-VCH GmbH
DOI: 10.1002/ADMA.202413017

Biodegradable, Humidity-Insensitive Mask-Integrated E-Nose for Sustainable and Non-Invasive Continuous Breath Analysis

Autores: Indrajit Mondal, Adan Zoabi, Hossam Haick
Publicado en: Advanced Functional Materials, Edición 2413017, 2025, ISSN 1616-3028
Editor: Wiley-VCH GmbH
DOI: 10.1002/ADFM.202425193

Pitfalls in interpreting calibration in comparative evaluations of risk models for precision lung cancer screening

Autores: Brenner, Hermann; Frick, Clara; Seum, Teresa; Bhardwaj, Megha
Publicado en: npj Precision Oncology, Edición 281, 2024, ISSN 2397-768X
Editor: Springer Nature
DOI: 10.1038/S41698-024-00785-6

Mobile Diagnostic Clinics

Autores: Roni Baron, Hossam Haick
Publicado en: ACS Sensors, Edición 9, 2024, ISSN 2379-3694
Editor: American Chemical Society (ACS)
DOI: 10.1021/acssensors.4c00636

Head-to-head comparisons of risk discrimination by questionnaire-based lung cancer risk prediction models: a systematic review and meta-analysis

Autores: Clara Frick; Teresa Seum; Megha Bhardwaj; Tim Holland-Letz; Ben Schöttker; Hermann Brenner
Publicado en: eClinicalMedicine, 2025, ISSN 2589-5370
Editor: The Lancet Group
DOI: 10.1016/J.ECLINM.2025.103075

Next generation proteomics improves lung cancer risk prediction.

Autores: Megha Bhardwaj, Clara Frick, Ben Schöttker, B Holleczek, Hermann Brenner
Publicado en: Molecular Oncology, Edición early view, 2025, ISSN 1574-7891
Editor: Elsevier BV
DOI: 10.1002/1878-0261.70166

Conference proceedings (3)

Risk-adapted lung cancer screening starting ages for former smokers

Autores: Clara Frick, Lara R Hallson, Uwe Siebert, Megha Bhardwaj, Ben Schöttker, Hermann Brenner
Publicado en: Edición 15, 2025
Editor: NKI Netherlands Cancer Institute

Lung-CABO: Lung Cancer Concepts Association Biological Ontology

Autores: Delia Aminta Moreno-Perdomo, Paloma Tejera-Nevado, Lucía Prieto-Santamaría, Guillermo Vigueras, Antonio Jesus Diaz-Honrubia, Alejandro Rodríguez-González
Publicado en: 2025 IEEE 38th International Symposium on Computer-Based Medical Systems (CBMS), 2025, ISSN 2372-9198
Editor: IEEE
DOI: 10.1109/CBMS65348.2025.00136

Survival Stacking Ensemble Model for Lung Cancer Risk Prediction

Autores: Alonso, Eduardo; Calle, Xabier; Gurrutxaga, Ibai; Beristain, Andoni
Publicado en: Studies in Health Technology and Informatics ISBN: 9781643685540, Edición 321, 2024
Editor: IOS Press Ebooks
DOI: 10.3233/SHTI241083

Monographic books (1)

Nature-Inspired Sensors

Autores: Haick, H.
Publicado en: 2024
Editor: Elsevier
DOI: 10.1016/C2022-0-01670-6

Other (1)

Transforming Lung Cancer Screening – Insights from the LUCIA Social Lab

Autores: Yaghma B. V. (Ivett Jakab, Emad Yaghmaei)
Publicado en: 2025
Editor: Yaghma