Understanding Lung Cancer related risk factors and their Impact

Informacje na temat projektu

LUCIA

Identyfikator umowy o grant: 101096473

DOI

10.3030/101096473

Data podpisania przez KE 5 Grudnia 2022

Data rozpoczęcia 1 Stycznia 2023

Data zakończenia 31 Grudnia 2026

Finansowanie w ramach

• Health

Koszt całkowity

€ 13 516 869,00

Wkład UE

€ 13 516 869,00

Koordynowany przez

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (10)

Clinical protocol and regulatory authorization report: General population Screening

Clinical protocol for the cohort study in the general population screening and the regulatory authorizations will be collected.

Common work plan for scientific collaboration under the ‘Understanding’ cluster
Communication, Dissemination and Exploitation Plan

Outlines the key activities, identifies stakeholders, and provides timelines, and indicators, including project website release.

Policy brief formulating recommendations based on the research and innovation strand of the ‘Understanding’ annual cluster meeting-M12
Data Management Plan-6M

Document describing the principles and initial plans of the project for data management (M06).The preparation of the Data Management Plan will include a common chapter on the ‘Understanding’ cluster. The aim of the chapter is to address commonalities in data standards, data validation, data protection and fostering data exchange, in particular when it comes to sharing project data with a future federated UNCAN.eu data platform. Therefore, interactions are envisaged with the 4.UNCAN.eu (http://uncaninitiative.eu/) coordination and support action which is preparing a blueprint for UNCAN.eu.

Conclusions of common annual meeting of the ‘Understanding’ cluster-M12
Policy brief formulating recommendations based on the research and innovation strand of the ‘Understanding’ annual cluster meeting-M24
Conclusions of common annual meeting of the ‘Understanding’ cluster-M24
LUCIA Management Report-9M

LUCIA Management Report- Initial report on M9 describing IPR, impact, and technology steering aspects of the project.

Clinical protocol and regulatory authorization report: Precision Screening and Diagnosis

The design of clinical protocol established by the clinical partners for the precision screening and diagnosis phases and the regulatory authorizations will be collected.

Websites, patent fillings, videos etc. (2)

Project website maintenance
Common video and/or a common cluster brochure

Common video and/or a common cluster brochure (cluster 'understanding')

Publikacje

Peer reviewed articles (24)

Short-term effects of electronic cigarette smoking on cardiorespiratory parameters, volatile organic compounds and inflammatory markers

Autorzy: Suha Rizik; Ronen Bar-Yoseph; Moneera Hanna; Fahed Hakim; Yoav Broza; Amir Sader; Yazeed Toukan; Hossam Haick; Lea Bentur; Michal Gur
Opublikowane w: ERJ Open Research, Numer 01096-2024, 2025, ISSN 2312-0541
Wydawca: European Respiratory Society (ERS)
DOI: 10.1183/23120541.01096-2024

Scientific Reports

Autorzy: Jacob Levman; Yoav Y. Broza
Opublikowane w: Scientific Reports, Numer 9436, 2025, ISSN 2045-2322
Wydawca: Springer Nature
DOI: 10.1038/S41598-025-89820-5

Variable efficiency of nonsense-mediated mRNA decay across human tissues, tumors and individuals

Autorzy: Guillermo Palou-Márquez; Fran Supek
Opublikowane w: Genome Biology, Numer 316, 2024, ISSN 1474-760X
Wydawca: Springer Nature
DOI: 10.1186/S13059-025-03727-Y

Nature Communications

Autorzy: Ahmed Khalil; Fran Supek
Opublikowane w: Nature Communications, Numer 16 (42209), 2025, ISSN 2041-1723
Wydawca: Nature Portfolio
DOI: 10.1038/S41467-025-59397-8

Genome-scale quantification and prediction of pathogenic stop codon readthrough by small molecules

Autorzy: Ignasi Toledano; Fran Supek; Ben Lehner
Opublikowane w: Nature Genetics, 2024, ISSN 1546-1718
Wydawca: Nature Portfolio
DOI: 10.1101/2023.08.07.552350

Next‐Gen Wearables Unlocking Chemical Secrets

Autorzy: Hossam Haick
Opublikowane w: Advanced Sensor Research, Numer 3, 2024, ISSN 2751-1219
Wydawca: Wiley
DOI: 10.1002/adsr.202300203

Genome Medicine

Autorzy: Ferrer-Torres, Patricia; Galvan-Femenia, Ivan; Supek, Fran
Opublikowane w: Genome Medicine, Numer 76, 2025, ISSN 1756-994X
Wydawca: BioMed Central
DOI: 10.1186/S13073-025-01497-7

Computers in Biology and Medicine

Autorzy: B. Farina, R. Carbajo Benito, D. Montalvo-García, D. Bermejo-Peláez, L. Seijo Maceiras, M.J. Ledesma-Carbayo
Opublikowane w: Computers in Biology and Medicine, Numer 196, 2025, ISSN 0010-4825
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/J.COMPBIOMED.2025.110813

Risk-Adapted Lung Cancer Screening Starting Ages for Former Smokers

Autorzy: Clara Frick, Lára R. Hallsson, Uwe Siebert, Megha Bhardwaj, Ben Schöttker, Hermann Brenner
Opublikowane w: JAMA Network Open, Numer 8, 2025, ISSN 2574-3805
Wydawca: American Medical Association (AMA)
DOI: 10.1001/JAMANETWORKOPEN.2025.51281

Nature Communications

Autorzy: Jian Yang; Xia Gong; Ying Zheng; Hong Duan; Shuijin Chen; Tong Wu; Changqing Yi; Lelun Jiang; Hossam Haick
Opublikowane w: Nature Communications, Numer 16 (6260), 2025, ISSN 2041-1723
Wydawca: Nature Portfolio
DOI: 10.1038/S41467-025-61549-9

Long Term Evaluation of Quantitative Cumulative Irradiation in Patients Suffering from ILDs

Autorzy: Berg, Julien; Frix, Anne-Noëlle; Henket, Monique; GESTER, Fanny; Winandy, Marie-Laurence; CANIVET, Perrine; Njock, Makon-Sébastien; THYS, Marie; DESIR, Colin; Meunier, Paul; Louis, Renaud; Malchair,
Opublikowane w: Diagnostics, Numer 14(19), 2024, ISSN 2075-4418
Wydawca: MDPI
DOI: 10.3390/DIAGNOSTICS14192136

Nature Communications

Autorzy: Elizaveta Besedina; Fran Supek
Opublikowane w: Nature Communications, Numer 15 (6139), 2024, ISSN 2041-1723
Wydawca: Nature Portfolio
DOI: 10.1038/S41467-024-50552-1

Spin-induced nanomaterials for detection of chiral volatile organic compounds

Autorzy: Arnab Maity, Hossam Haick
Opublikowane w: Applied Physics Reviews, Numer 10, 2023, ISSN 1931-9401
Wydawca: AIP Publishing
DOI: 10.1063/5.0146656

Self‐Sustaining Triboelectric Nanosensors for Real‐Time Urine Analysis in Smart Toilets

Autorzy: Indrajit Mondal, Elias Mansour, Youbin Zheng, Ritu Gupta, Hossam Haick
Opublikowane w: Small, 2024, ISSN 1613-6810
Wydawca: Wiley
DOI: 10.1002/smll.202403385

Protocol to fabricate wearable stretchable microneedle-based sensors

Autorzy: Rawan Omar, Youbin Zheng, Hossam Haick
Opublikowane w: STAR Protocols, 2023, ISSN 2666-1667
Wydawca: Cell Press
DOI: 10.1016/j.xpro.2023.102751

Spin‐Controlled Helical Quantum Sieve Chiral Spectrometer

Autorzy: Arnab Maity, Yael Hershkovitz‐Pollak, Ritu Gupta, Weiwei Wu, Hossam Haick
Opublikowane w: Advanced Materials, Numer 35, 2023, ISSN 0935-9648
Wydawca: Wiley
DOI: 10.1002/adma.202209125

Advances in volatile organic compounds detection: From fundamental research to real-world applications

Autorzy: Haick, H.
Opublikowane w: Applied Physics Review, Numer 11, 2024, ISSN 1931-9401
Wydawca: AIP Publishing
DOI: 10.1063/5.0230205

Liquid Biopsy-Based Volatile Organic Compounds from Blood and Urine and Their Combined Data Sets for Highly Accurate Detection of Cancer

Autorzy: Reef Einoch Amor, Jeremy Levy, Yoav Y. Broza, Reinis Vangravs, Shelley Rapoport, Min Zhang, Weiwei Wu, Marcis Leja, Joachim A. Behar, Hossam Haick
Opublikowane w: ACS Sensors, Numer 8, 2023, ISSN 2379-3694
Wydawca: American Chemical Society (ACS)
DOI: 10.1021/acssensors.2c02422

Chemical Tomography of Cancer Organoids and Cyto‐Proteo‐Genomic Development Stages Through Chemical Communication Signals

Autorzy: Arnab Maity; Vivian Darsa Maidantchik; Keren Weidenfeld; Sarit Larisch; Dalit Barkan; Hossam Haick
Opublikowane w: Advanced Materials, Numer 2413017, 2025, ISSN 1521-4095
Wydawca: Wiley-VCH GmbH
DOI: 10.1002/ADMA.202413017

Biodegradable, Humidity-Insensitive Mask-Integrated E-Nose for Sustainable and Non-Invasive Continuous Breath Analysis

Autorzy: Indrajit Mondal, Adan Zoabi, Hossam Haick
Opublikowane w: Advanced Functional Materials, Numer 2413017, 2025, ISSN 1616-3028
Wydawca: Wiley-VCH GmbH
DOI: 10.1002/ADFM.202425193

Pitfalls in interpreting calibration in comparative evaluations of risk models for precision lung cancer screening

Autorzy: Brenner, Hermann; Frick, Clara; Seum, Teresa; Bhardwaj, Megha
Opublikowane w: npj Precision Oncology, Numer 281, 2024, ISSN 2397-768X
Wydawca: Springer Nature
DOI: 10.1038/S41698-024-00785-6

Mobile Diagnostic Clinics

Autorzy: Roni Baron, Hossam Haick
Opublikowane w: ACS Sensors, Numer 9, 2024, ISSN 2379-3694
Wydawca: American Chemical Society (ACS)
DOI: 10.1021/acssensors.4c00636

Head-to-head comparisons of risk discrimination by questionnaire-based lung cancer risk prediction models: a systematic review and meta-analysis

Autorzy: Clara Frick; Teresa Seum; Megha Bhardwaj; Tim Holland-Letz; Ben Schöttker; Hermann Brenner
Opublikowane w: eClinicalMedicine, 2025, ISSN 2589-5370
Wydawca: The Lancet Group
DOI: 10.1016/J.ECLINM.2025.103075

Next generation proteomics improves lung cancer risk prediction.

Autorzy: Megha Bhardwaj, Clara Frick, Ben Schöttker, B Holleczek, Hermann Brenner
Opublikowane w: Molecular Oncology, Numer early view, 2025, ISSN 1574-7891
Wydawca: Elsevier BV
DOI: 10.1002/1878-0261.70166

Conference proceedings (3)

Risk-adapted lung cancer screening starting ages for former smokers

Autorzy: Clara Frick, Lara R Hallson, Uwe Siebert, Megha Bhardwaj, Ben Schöttker, Hermann Brenner
Opublikowane w: Numer 15, 2025
Wydawca: NKI Netherlands Cancer Institute

Lung-CABO: Lung Cancer Concepts Association Biological Ontology

Autorzy: Delia Aminta Moreno-Perdomo, Paloma Tejera-Nevado, Lucía Prieto-Santamaría, Guillermo Vigueras, Antonio Jesus Diaz-Honrubia, Alejandro Rodríguez-González
Opublikowane w: 2025 IEEE 38th International Symposium on Computer-Based Medical Systems (CBMS), 2025, ISSN 2372-9198
Wydawca: IEEE
DOI: 10.1109/CBMS65348.2025.00136

Survival Stacking Ensemble Model for Lung Cancer Risk Prediction

Autorzy: Alonso, Eduardo; Calle, Xabier; Gurrutxaga, Ibai; Beristain, Andoni
Opublikowane w: Studies in Health Technology and Informatics ISBN: 9781643685540, Numer 321, 2024
Wydawca: IOS Press Ebooks
DOI: 10.3233/SHTI241083

Monographic books (1)

Nature-Inspired Sensors

Autorzy: Haick, H.
Opublikowane w: 2024
Wydawca: Elsevier
DOI: 10.1016/C2022-0-01670-6

Other (1)

Transforming Lung Cancer Screening – Insights from the LUCIA Social Lab

Autorzy: Yaghma B. V. (Ivett Jakab, Emad Yaghmaei)
Opublikowane w: 2025
Wydawca: Yaghma