Projektbeschreibung
Ausbau der Genomikkapazitäten zur Bewältigung von Epidemien in Afrika
Infektionen mit Krankheitserregern stellen in Afrika eine große Herausforderung dar, was die Notwendigkeit verbesserter Diagnostik, Überwachung und klinischer Behandlung bei aktuellen und künftigen Epidemien in der Region unterstreicht. Das Team des EU-finanzierten Projekts GenPath Africa widmet sich der Bekämpfung von Infektionen mit Krankheitserregern in Afrika. Das Projekt zielt darauf ab, die Genomikkapazitäten zu erhöhen und arzneimittelresistente HIV-1-Infektionen und Tuberkulose durch Präzisionsmedizin zu bekämpfen. Außerdem soll die genomische Epidemiologie als Grundlage für Strategien im Bereich der öffentlichen Gesundheit dienen. Das Projektteam wird fortschrittliche Methoden zum Nachweis neu auftretender Krankheitserreger anwenden, Schulungen in Südafrika anbieten, Technologie an das National Public Health Institute von Mosambik weitergeben und Verbindungen zwischen der Africa CDC Pathogen Genomics Initiative (Africa PGI) und öffentlichen Genomikeinrichtungen in Südafrika und Kenia herstellen.
Ziel
The overall goal of GenPath Africa is to control pathogen infections in Africa. Our consortium of African and European investigators proposes to build on our collective experience in responding to SARS-CoV-2 to better diagnose, monitor and clinically manage current and future epidemics in Africa. We propose to expand genomics capacity to combat drug resistant HIV-1 and TB through precision medicine and by using genomic epidemiology to guide the public health response. GenPath Africa will also apply recent developments in wastewater and one health surveillance to detect emerging pathogens. Capacity development activities will include degree training in South Africa and the transfer of technology to the National Public Health Institute of Mozambique.
The consortium’s objectives will be achieved by connecting the specialized genomics facilities of the Africa CDC Pathogen Genomics Initiative (Africa PGI) in South Africa and Kenya with African national public health institutes to translate scientific advances into public health actions. Long-term collaborations with Germany and Belgium will be leveraged to help achieve these objectives and make precision medicine and precision public health a reality in southern and East Africa. The consortium will also contribute to the long-term capacity building objectives of Africa PGI by contributing to harmonising training resources and collaboration with existing networks to ensure that all data are of high quality and available in public databases.
GenPath Africa will advance the EDTCP3 work program by: i) providing researchers and public health professionals with skills in genomic epidemiology to better understand infectious disease epidemiology and drug resistance, ii) strengthening capability in southern and East Africa to rapidly respond to current and emerging epidemics, and iii) providing researchers with training to advance their scientific careers in Africa and establish themselves as scientific and public health leaders.
Wissenschaftliches Gebiet
- natural sciencesbiological sciencesgenetics
- medical and health scienceshealth sciencespublic healthepidemiology
- medical and health scienceshealth sciencesinfectious diseases
- medical and health sciencesbasic medicinepharmacology and pharmacydrug resistance
- medical and health scienceshealth sciencespersonalized medicine
Schlüsselbegriffe
Programm/Programme
- HORIZON.2.1 - Health Main Programme
Aufforderung zur Vorschlagseinreichung
Andere Projekte für diesen Aufruf anzeigenFinanzierungsplan
HORIZON-JU-RIA - HORIZON JU Research and Innovation ActionsKoordinator
7600 Stellenbosch
Südafrika