image-Guided computational and experimental Analysis of fractured Patients

Información del proyecto

GAP

Identificador del acuerdo de subvención: 101120290

DOI

10.3030/101120290

Fecha de la firma de la CE 22 Junio 2023

Fecha de inicio 1 Octubre 2023

Fecha de finalización 31 Mayo 2028

Financiado con arreglo a

• Marie Skłodowska-Curie Actions (MSCA)

Coste total

Sin datos

Aportación de la UE

€ 2 679 933,60

Coordinado por

POLITECNICO DI MILANO
Italy

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Other (4)

A quantitative framework based on neural network for bone micro-cracks description and classification

A quantitative framework based on neural network for bone micro-cracks description and classification: identification of crack parameters from convolutional neural network processing

A quantitative framework based on topological and geometry approach for bone micro-cracks description and classification

A quantitative framework based on topological and geometry approach for bone micro-cracks description and classification: Extraction of a topological score of bone quality, Morse smale complexes and persistent homology

Network-wide events

Network-wide events Preparation of different events with target audience ranging from scientists, to clinicians, patients, companiesThis deliverable is due to month 22 and 42 (for each periodic report)

Development of meso and micro-scale numerical analyses

Development of meso and micro-scale numerical analyses: Application of multi-scale modelling techniques to predict multi-scale damage evolution via fracture mechanics parameters

Websites, patent fillings, videos etc. (1)

Website

Generation of GAP social profiles, including GAP official website, LinkedIn, and other social media

Documents, reports (2)

Definition and validation of micro-scale fragility indices

Definition and validation of micro-scale fragility indices: A micro-scale fragility index able to predict fracture onset with accuracy>90% and experimental validation with histologies

Mechanical multi-scale and biological characterization of healthy and pathological bone samples

Mechanical multi-scale characterization of healthy and pathological bone samples: meso (10 mm, testing device), micro (1 µm, synchrotron, SEM), nano (10 nm, FIB, Raman spectroscopy)Biological characterization of healthy and pathological bone samples: Characterization of osteoporosis, osteoarthrosis and Covid-19 samples via cell parameters from histologies, immunohistochemical analyses

Publicaciones

Peer reviewed articles (7)

Using crack face displacement to measure stress intensity: A practical approach

Autores: Anis Allahdiniyan, David Taylor
Publicado en: Theoretical and Applied Fracture Mechanics, Edición 138, 2025, ISSN 0167-8442
Editor: Elsevier BV
DOI: 10.1016/J.TAFMEC.2025.104940

Multifunctional in situ imaging of biological materials under load: A synchrotron-based platform for large-scale image-guided failure analysis

Autores: L. Clementini, F. Buccino, R. Palazzetti, E. Longo, M.Kudrna Prasek, G. Banfi, Z. Qin, L.M. Vergani
Publicado en: Materials & Design, Edición 257, 2025, ISSN 0264-1275
Editor: Elsevier BV
DOI: 10.1016/J.MATDES.2025.114408

Tuning mechanical response of nonuniform triangular lattice material via graph neural network based inverse design algorithm

Autores: Giuseppe Bonfanti, Federica Buccino, Laura Maria Vergani, Chao Gao
Publicado en: Procedia Structural Integrity, Edición 68, 2025, ISSN 2452-3216
Editor: Elsevier BV
DOI: 10.1016/J.PROSTR.2025.06.166

Exploring the Potential of ATUM-SEM for Enhanced Characterization of Human Trabecular Bone in Biomaterials Research

Autores: Valeria Vistoso, Tom Ferté, Federica Buccino, Laura Vergani, Ovidiu Ersen, Adele Carradó
Publicado en: JOM, 2025, ISSN 1047-4838
Editor: Springer Science and Business Media LLC
DOI: 10.1007/S11837-025-07212-6

Integration of Multi-Scale Predictive Tools of Bone Fragility: A Structural and Material Property Perspective

Autores: Muhammad Ateeq, Laura Vergani, Federica Buccino
Publicado en: Materials, Edición 18, 2025, ISSN 1996-1944
Editor: MDPI AG
DOI: 10.3390/MA18194639

Sustainable silk fibroin scaffolds for bone repair: assessing their osteogenic potential via AI-enhanced synchrotron imaging workflow

Autores: G. Dei Rossi, F. Buccino, E. Longo, G. Tromba, L.M. Vergani
Publicado en: Biomaterials Advances, Edición 181, 2025, ISSN 2772-9508
Editor: Elsevier BV
DOI: 10.1016/J.BIOADV.2025.214658

Structural influences on bone tissue engineering: A review and perspective

Autores: Sara Sebastiani, Federica Buccino, Zhao Qin, Laura Maria Vergani
Publicado en: Matter, Edición 8, 2025, ISSN 2590-2385
Editor: Elsevier BV
DOI: 10.1016/J.MATT.2025.102252