image-Guided computational and experimental Analysis of fractured Patients

Informations projet

GAP

N° de convention de subvention: 101120290

DOI

10.3030/101120290

Date de signature de la CE 22 Juin 2023

Date de début 1 Octobre 2023

Date de fin 31 Mai 2028

Financé au titre de

• Marie Skłodowska-Curie Actions (MSCA)

Coût total

Aucune donnée

Contribution de l’UE

€ 2 679 933,60

Coordonné par

POLITECNICO DI MILANO
Italy

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Other (4)

A quantitative framework based on neural network for bone micro-cracks description and classification

A quantitative framework based on neural network for bone micro-cracks description and classification: identification of crack parameters from convolutional neural network processing

A quantitative framework based on topological and geometry approach for bone micro-cracks description and classification

A quantitative framework based on topological and geometry approach for bone micro-cracks description and classification: Extraction of a topological score of bone quality, Morse smale complexes and persistent homology

Network-wide events

Network-wide events Preparation of different events with target audience ranging from scientists, to clinicians, patients, companiesThis deliverable is due to month 22 and 42 (for each periodic report)

Development of meso and micro-scale numerical analyses

Development of meso and micro-scale numerical analyses: Application of multi-scale modelling techniques to predict multi-scale damage evolution via fracture mechanics parameters

Websites, patent fillings, videos etc. (1)

Website

Generation of GAP social profiles, including GAP official website, LinkedIn, and other social media

Documents, reports (2)

Definition and validation of micro-scale fragility indices

Definition and validation of micro-scale fragility indices: A micro-scale fragility index able to predict fracture onset with accuracy>90% and experimental validation with histologies

Mechanical multi-scale and biological characterization of healthy and pathological bone samples

Mechanical multi-scale characterization of healthy and pathological bone samples: meso (10 mm, testing device), micro (1 µm, synchrotron, SEM), nano (10 nm, FIB, Raman spectroscopy)Biological characterization of healthy and pathological bone samples: Characterization of osteoporosis, osteoarthrosis and Covid-19 samples via cell parameters from histologies, immunohistochemical analyses

Publications

Peer reviewed articles (7)

Using crack face displacement to measure stress intensity: A practical approach

Auteurs: Anis Allahdiniyan, David Taylor
Publié dans: Theoretical and Applied Fracture Mechanics, Numéro 138, 2025, ISSN 0167-8442
Éditeur: Elsevier BV
DOI: 10.1016/J.TAFMEC.2025.104940

Multifunctional in situ imaging of biological materials under load: A synchrotron-based platform for large-scale image-guided failure analysis

Auteurs: L. Clementini, F. Buccino, R. Palazzetti, E. Longo, M.Kudrna Prasek, G. Banfi, Z. Qin, L.M. Vergani
Publié dans: Materials & Design, Numéro 257, 2025, ISSN 0264-1275
Éditeur: Elsevier BV
DOI: 10.1016/J.MATDES.2025.114408

Tuning mechanical response of nonuniform triangular lattice material via graph neural network based inverse design algorithm

Auteurs: Giuseppe Bonfanti, Federica Buccino, Laura Maria Vergani, Chao Gao
Publié dans: Procedia Structural Integrity, Numéro 68, 2025, ISSN 2452-3216
Éditeur: Elsevier BV
DOI: 10.1016/J.PROSTR.2025.06.166

Exploring the Potential of ATUM-SEM for Enhanced Characterization of Human Trabecular Bone in Biomaterials Research

Auteurs: Valeria Vistoso, Tom Ferté, Federica Buccino, Laura Vergani, Ovidiu Ersen, Adele Carradó
Publié dans: JOM, 2025, ISSN 1047-4838
Éditeur: Springer Science and Business Media LLC
DOI: 10.1007/S11837-025-07212-6

Integration of Multi-Scale Predictive Tools of Bone Fragility: A Structural and Material Property Perspective

Auteurs: Muhammad Ateeq, Laura Vergani, Federica Buccino
Publié dans: Materials, Numéro 18, 2025, ISSN 1996-1944
Éditeur: MDPI AG
DOI: 10.3390/MA18194639

Sustainable silk fibroin scaffolds for bone repair: assessing their osteogenic potential via AI-enhanced synchrotron imaging workflow

Auteurs: G. Dei Rossi, F. Buccino, E. Longo, G. Tromba, L.M. Vergani
Publié dans: Biomaterials Advances, Numéro 181, 2025, ISSN 2772-9508
Éditeur: Elsevier BV
DOI: 10.1016/J.BIOADV.2025.214658

Structural influences on bone tissue engineering: A review and perspective

Auteurs: Sara Sebastiani, Federica Buccino, Zhao Qin, Laura Maria Vergani
Publié dans: Matter, Numéro 8, 2025, ISSN 2590-2385
Éditeur: Elsevier BV
DOI: 10.1016/J.MATT.2025.102252