image-Guided computational and experimental Analysis of fractured Patients

Informazioni relative al progetto

GAP

ID dell’accordo di sovvenzione: 101120290

DOI

10.3030/101120290

Data della firma CE 22 Giugno 2023

Data di avvio 1 Ottobre 2023

Data di completamento 31 Maggio 2028

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 2 679 933,60

Coordinato da

POLITECNICO DI MILANO
Italy

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (4)

A quantitative framework based on neural network for bone micro-cracks description and classification

A quantitative framework based on neural network for bone micro-cracks description and classification: identification of crack parameters from convolutional neural network processing

A quantitative framework based on topological and geometry approach for bone micro-cracks description and classification

A quantitative framework based on topological and geometry approach for bone micro-cracks description and classification: Extraction of a topological score of bone quality, Morse smale complexes and persistent homology

Network-wide events

Network-wide events Preparation of different events with target audience ranging from scientists, to clinicians, patients, companiesThis deliverable is due to month 22 and 42 (for each periodic report)

Development of meso and micro-scale numerical analyses

Development of meso and micro-scale numerical analyses: Application of multi-scale modelling techniques to predict multi-scale damage evolution via fracture mechanics parameters

Websites, patent fillings, videos etc. (1)

Website

Generation of GAP social profiles, including GAP official website, LinkedIn, and other social media

Documents, reports (2)

Definition and validation of micro-scale fragility indices

Definition and validation of micro-scale fragility indices: A micro-scale fragility index able to predict fracture onset with accuracy>90% and experimental validation with histologies

Mechanical multi-scale and biological characterization of healthy and pathological bone samples

Mechanical multi-scale characterization of healthy and pathological bone samples: meso (10 mm, testing device), micro (1 µm, synchrotron, SEM), nano (10 nm, FIB, Raman spectroscopy)Biological characterization of healthy and pathological bone samples: Characterization of osteoporosis, osteoarthrosis and Covid-19 samples via cell parameters from histologies, immunohistochemical analyses

Pubblicazioni

Peer reviewed articles (7)

Using crack face displacement to measure stress intensity: A practical approach

Autori: Anis Allahdiniyan, David Taylor
Pubblicato in: Theoretical and Applied Fracture Mechanics, Numero 138, 2025, ISSN 0167-8442
Editore: Elsevier BV
DOI: 10.1016/J.TAFMEC.2025.104940

Multifunctional in situ imaging of biological materials under load: A synchrotron-based platform for large-scale image-guided failure analysis

Autori: L. Clementini, F. Buccino, R. Palazzetti, E. Longo, M.Kudrna Prasek, G. Banfi, Z. Qin, L.M. Vergani
Pubblicato in: Materials & Design, Numero 257, 2025, ISSN 0264-1275
Editore: Elsevier BV
DOI: 10.1016/J.MATDES.2025.114408

Tuning mechanical response of nonuniform triangular lattice material via graph neural network based inverse design algorithm

Autori: Giuseppe Bonfanti, Federica Buccino, Laura Maria Vergani, Chao Gao
Pubblicato in: Procedia Structural Integrity, Numero 68, 2025, ISSN 2452-3216
Editore: Elsevier BV
DOI: 10.1016/J.PROSTR.2025.06.166

Exploring the Potential of ATUM-SEM for Enhanced Characterization of Human Trabecular Bone in Biomaterials Research

Autori: Valeria Vistoso, Tom Ferté, Federica Buccino, Laura Vergani, Ovidiu Ersen, Adele Carradó
Pubblicato in: JOM, 2025, ISSN 1047-4838
Editore: Springer Science and Business Media LLC
DOI: 10.1007/S11837-025-07212-6

Integration of Multi-Scale Predictive Tools of Bone Fragility: A Structural and Material Property Perspective

Autori: Muhammad Ateeq, Laura Vergani, Federica Buccino
Pubblicato in: Materials, Numero 18, 2025, ISSN 1996-1944
Editore: MDPI AG
DOI: 10.3390/MA18194639

Sustainable silk fibroin scaffolds for bone repair: assessing their osteogenic potential via AI-enhanced synchrotron imaging workflow

Autori: G. Dei Rossi, F. Buccino, E. Longo, G. Tromba, L.M. Vergani
Pubblicato in: Biomaterials Advances, Numero 181, 2025, ISSN 2772-9508
Editore: Elsevier BV
DOI: 10.1016/J.BIOADV.2025.214658

Structural influences on bone tissue engineering: A review and perspective

Autori: Sara Sebastiani, Federica Buccino, Zhao Qin, Laura Maria Vergani
Pubblicato in: Matter, Numero 8, 2025, ISSN 2590-2385
Editore: Elsevier BV
DOI: 10.1016/J.MATT.2025.102252