image-Guided computational and experimental Analysis of fractured Patients

Projektinformationen

GAP

ID Finanzhilfevereinbarung: 101120290

DOI

10.3030/101120290

EK-Unterschriftsdatum 22 Juni 2023

Startdatum 1 Oktober 2023

Enddatum 31 Mai 2028

Finanziert unter

• Marie Skłodowska-Curie Actions (MSCA)

Gesamtkosten

Keine Daten

EU-Beitrag

€ 2 679 933,60

Koordiniert durch

POLITECNICO DI MILANO
Italy

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Other (4)

A quantitative framework based on neural network for bone micro-cracks description and classification

A quantitative framework based on neural network for bone micro-cracks description and classification: identification of crack parameters from convolutional neural network processing

A quantitative framework based on topological and geometry approach for bone micro-cracks description and classification

A quantitative framework based on topological and geometry approach for bone micro-cracks description and classification: Extraction of a topological score of bone quality, Morse smale complexes and persistent homology

Network-wide events

Network-wide events Preparation of different events with target audience ranging from scientists, to clinicians, patients, companiesThis deliverable is due to month 22 and 42 (for each periodic report)

Development of meso and micro-scale numerical analyses

Development of meso and micro-scale numerical analyses: Application of multi-scale modelling techniques to predict multi-scale damage evolution via fracture mechanics parameters

Websites, patent fillings, videos etc. (1)

Website

Generation of GAP social profiles, including GAP official website, LinkedIn, and other social media

Documents, reports (2)

Definition and validation of micro-scale fragility indices

Definition and validation of micro-scale fragility indices: A micro-scale fragility index able to predict fracture onset with accuracy>90% and experimental validation with histologies

Mechanical multi-scale and biological characterization of healthy and pathological bone samples

Mechanical multi-scale characterization of healthy and pathological bone samples: meso (10 mm, testing device), micro (1 µm, synchrotron, SEM), nano (10 nm, FIB, Raman spectroscopy)Biological characterization of healthy and pathological bone samples: Characterization of osteoporosis, osteoarthrosis and Covid-19 samples via cell parameters from histologies, immunohistochemical analyses

Veröffentlichungen

Peer reviewed articles (7)

Using crack face displacement to measure stress intensity: A practical approach

Autoren: Anis Allahdiniyan, David Taylor
Veröffentlicht in: Theoretical and Applied Fracture Mechanics, Ausgabe 138, 2025, ISSN 0167-8442
Herausgeber: Elsevier BV
DOI: 10.1016/J.TAFMEC.2025.104940

Multifunctional in situ imaging of biological materials under load: A synchrotron-based platform for large-scale image-guided failure analysis

Autoren: L. Clementini, F. Buccino, R. Palazzetti, E. Longo, M.Kudrna Prasek, G. Banfi, Z. Qin, L.M. Vergani
Veröffentlicht in: Materials & Design, Ausgabe 257, 2025, ISSN 0264-1275
Herausgeber: Elsevier BV
DOI: 10.1016/J.MATDES.2025.114408

Tuning mechanical response of nonuniform triangular lattice material via graph neural network based inverse design algorithm

Autoren: Giuseppe Bonfanti, Federica Buccino, Laura Maria Vergani, Chao Gao
Veröffentlicht in: Procedia Structural Integrity, Ausgabe 68, 2025, ISSN 2452-3216
Herausgeber: Elsevier BV
DOI: 10.1016/J.PROSTR.2025.06.166

Exploring the Potential of ATUM-SEM for Enhanced Characterization of Human Trabecular Bone in Biomaterials Research

Autoren: Valeria Vistoso, Tom Ferté, Federica Buccino, Laura Vergani, Ovidiu Ersen, Adele Carradó
Veröffentlicht in: JOM, 2025, ISSN 1047-4838
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1007/S11837-025-07212-6

Integration of Multi-Scale Predictive Tools of Bone Fragility: A Structural and Material Property Perspective

Autoren: Muhammad Ateeq, Laura Vergani, Federica Buccino
Veröffentlicht in: Materials, Ausgabe 18, 2025, ISSN 1996-1944
Herausgeber: MDPI AG
DOI: 10.3390/MA18194639

Sustainable silk fibroin scaffolds for bone repair: assessing their osteogenic potential via AI-enhanced synchrotron imaging workflow

Autoren: G. Dei Rossi, F. Buccino, E. Longo, G. Tromba, L.M. Vergani
Veröffentlicht in: Biomaterials Advances, Ausgabe 181, 2025, ISSN 2772-9508
Herausgeber: Elsevier BV
DOI: 10.1016/J.BIOADV.2025.214658

Structural influences on bone tissue engineering: A review and perspective

Autoren: Sara Sebastiani, Federica Buccino, Zhao Qin, Laura Maria Vergani
Veröffentlicht in: Matter, Ausgabe 8, 2025, ISSN 2590-2385
Herausgeber: Elsevier BV
DOI: 10.1016/J.MATT.2025.102252