NEXT GENERATION TOOLS FOR GENOME-CENTRIC MULTIMODAL DATA INTEGRATION IN PERSONALISED CARDIOVASCULAR MEDICINE

Projektinformationen

NextGen

ID Finanzhilfevereinbarung: 101136962

DOI

10.3030/101136962

EK-Unterschriftsdatum 1 Dezember 2023

Startdatum 1 Januar 2024

Enddatum 31 Dezember 2027

Finanziert unter

• Health

Gesamtkosten

€ 7 601 771,25

EU-Beitrag

€ 7 601 770,00

Koordiniert durch

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

Periodic Reporting for period 1 - NextGen (NEXT GENERATION TOOLS FOR GENOME-CENTRIC MULTIMODAL DATA INTEGRATION IN PERSONALISED CARDIOVASCULAR MEDICINE)

Berichtszeitraum: 2024-01-01 bis 2025-06-30

Zusammenfassung vom Kontext und den Gesamtzielen des Projekts

The overall objective of NextGen is to build novel and synergistic tools to enable portable multimodal, multiomic and clinically-oriented research in high-impact areas of cardiovascular medicine. NextGen tools will benefit researchers, innovators and healthcare professionals by identifying and overcoming health data linkage barriers in exemplar use cases which are complex or intractable with existing technology. Consequently, it will benefit patients, providing faster diagnosis, and better treatments (including personalised medicine). A comprehensive gap analysis of the existing landscape, factoring in ongoing initiatives will ensure NextGen deliverables are forward-looking and complementary. In particular, the NextGen embedded governance framework and robust regulatory processes will ensure secure multi-jurisdictional phenotype and genomic data access aligned with initiatives including “1+ Million Genomes” and European Health Data Space.

Arbeit, die ab Beginn des Projekts bis zum Ende des durch den Bericht erfassten Berichtszeitraums geleistet wurde, und die wichtigsten bis dahin erzielten Ergebnisse

The project remains on track. Significant progress has been made in decentralized data management, architecture design, federated analytics, multimodal integration, governance, and stakeholder engagement. Pathfinder and MVP services have been deployed, laying the foundation for cross-jurisdictional interoperability, privacy-preserving data sharing, and sustainable exploitation of project results.

Fortschritte, die über den aktuellen Stand der Technik hinausgehen und voraussichtliche potenzielle Auswirkungen (einschließlich der bis dato erzielten sozioökonomischen Auswirkungen und weiter gefassten gesellschaftlichen Auswirkungen des Projekts)

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