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Aligning Brain Rhythms: Understanding the mechanisms of cortical tracking of speech to improve language functions with real time closed-loop neurofeedback

Project description

Cortical tracking of speech as language processing biomarker

Speech processing and reading are essential skills that influence social, educational and professional development. However, early biomarkers for learning disabilities such as developmental dyslexia (DD) and second language acquisition remain unexplored. The ERC-funded CORTICAL RHYTHMS project will use advanced neuroimaging tools and longitudinal studies to investigate cortical tracking of speech (CTS), a process that measures the alignment between fluctuations in speech signals and brain activity. It will explore CTS predictive capabilities and causal relationships in early language development, second language learning, reading, DD and illiteracy. Ultimately, it establishes CTS as a biomarker for language processing and to develop a real-time, closed-loop neurofeedback protocol. This protocol will enhance language learning and improve methods for diagnosing second language acquisition challenges and DD.

Objective

Speech processing and reading are essential unique human abilities underpinning social, educational, and professional advancement. However early biomarkers for learning disabilities such as Developmental Dyslexia (DD) and for second language learning have yet to be identified. Here, cutting edge neuroimaging tools, carefully designed tasks, and longitudinal designs will be used to record cortical tracking of speech (CTS), namely, the temporal alignment between fluctuations in the speech signal and fluctuations in electrical brain activity across different populations. Specifically, we will investigate the predictive ability and causality of CTS 1) at an early age in language development, 2) for second language learning, reading, DD and illiteracy, 3) establish the domain-specificity of CTS as ‘biomarker of language processing’, and 4) pioneer a real-time closed-loop neurofeedback protocol modulating CTS to adaptively change language processing and learning through neurofeedback. This project represents a radically new scientific approach that will break new ground by investigating the predictive ability of CTS that combined with longitudinal designs and real-time closed-loop neurofeedback will allow us to (1) establish causal relationships and (2) use this novel approach to improve L2 learning and to diagnose and remediate DD.

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Programme(s)

Topic(s)

Funding Scheme

HORIZON-ERC - HORIZON ERC Grants

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Call for proposal

(opens in new window) ERC-2023-ADG

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Host institution

BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE
Net EU contribution
€ 2 500 000,00
Address
PASEO MIKELETEGI 69 2
20009 San Sebastian
Spain
Region
Noreste País Vasco Gipuzkoa
Activity type
Research Organisations
Links
Total cost
€ 2 500 000,00

Beneficiaries (1)