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Graphene-enzyme-based nanohybrid agent to overcome environmental and sustainability thresholds in water management systems

Descrizione del progetto

Un nuovo agente nanoibrido bioattivo per sviluppare strategie anti-bioincrostazioni

Le bioincrostazioni superficiali rappresentano una sfida globale significativa per le operazioni marittime, la gestione idrica e i sistemi alimentari e delle bevande, principalmente a causa dell’accumulo di microrganismi sulle superfici a contatto con l’acqua, che determina la formazione di biofilm. Questi biofilm possono ospitare agenti patogeni in grado di provocare malattie, nonché contribuire alla corrosione influenzata dai microbi; le attuali strategie anti-bioincrostazioni, spesso basate su agenti tossici, non riescono a prevenirne efficacemente la formazione. Sostenuto dal programma di azioni Marie Skłodowska-Curie, il progetto BioNanoAct si propone di sviluppare un nuovo agente nanoibrido bioattivo attraverso la sintesi di nanoparticelle metalliche all’interno di matrici di bio-grafene innestate con enzimi. Questi nanoibridi saranno quindi utilizzati per produrre rivestimenti nanocompositi dotati di proprietà di lunga durata per contrastare le bioincrostazioni e la corrosione influenzata dai microbi. Inoltre, il progetto si prefigge di promuovere la collaborazione tra ricercatori e professionisti del settore con l’obiettivo di far progredire le strategie di mitigazione delle bioincrostazioni.

Obiettivo

Biofouling on surfaces is one of the most pressing global threats, exacerbated by the world growing population and subsequent industrial activities, as well as climate change. It affects all societal infrastructures, including maritime operations, water management and food/beverage systems. The main problem underlying all these infrastructures is the colonisation of microorganisms on water-contact surfaces, forming biofilms. Biofilms can harbour microbial populations of disease-causing pathogens, which are associated with waterborne disease outbreaks that occur every year worldwide, and their disinfection is currently a critical and challenging process. Biofilms are also associated with Microbially Influenced Corrosion (MIC), which is estimated to affect up to 20% of corrosion in water management systems, costing billions of dollars only for rehabilitation. Hitherto, the most effective anti-biofouling strategies rely on the release of toxic and persistent bioactive agents, remaining ineffective to prevent biofilm formation on surfaces under the current demand and environmental guidelines. Under BioNanoAct, a new bioactive bio-nanohybrid agent generated by the in-situ synthesis of metal nanoparticles in enzyme-grafted bio-graphene matrices will be developed and immobilised in polymeric formulations to produce novel nanocomposite coatings with long-lasting anti-fouling and anti-MIC protective effects on surfaces. These multifunctional bio-based nanomaterials will overcome current limitations in biofouling mitigation and enable scientific breakthroughs, particularly in synthesis and grafting methodologies, as well as in the interaction between biofilm-smart material and engineered waterborne systems. This project will also bring together researchers and industry professionals working on state-of-the-art strategies for biofouling mitigation and MIC that will provide interdisciplinary training and a solid platform for knowledge transfer to the MSCA researcher.

Coordinatore

FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS
Contribution nette de l'UE
€ 156 778,56
Indirizzo
CAMPO GRANDE, EDIFICIO C1, PISO 3
1749 016 Lisbon
Portogallo

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