Developing and implementing VIrtual Control groups To reducE animal use in toxicology Research

Project Information

VICT3R

Grant agreement ID: 101172693

DOI

10.3030/101172693

EC signature date 26 July 2024

Start date 1 September 2024

End date 29 February 2028

Funded under

• Health

Total cost

€ 26 995 885,75

EU contribution

€ 13 524 750,00

Coordinated by

UNIVERSIDAD POMPEU FABRA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Challenges and opportunities for validation of AI-based new approach methods

Published in: ALTEX, Issue 42, 2025, ISSN 1868-596X
Publisher: ALTEX Edition
DOI: 10.14573/altex.2412291

The validation of regulatory test methods – Conceptual, ethical, and philosophical foundations

Published in: ALTEX, Issue 41, 2024, ISSN 1868-596X
Publisher: ALTEX Edition
DOI: 10.14573/altex.2409271

Transitional initiatives for advancing the phasing out of the use of animals for drug and chemical safety testing: The IHI VICT3R project for reducing the use of animals by implementing virtual control groups

Author(s): Ferran Sanz, Julia Matyjasiak, Javier Orihuel, Colleen M. Pike, Inari Soininen, Frank Bringezu, Olga Valverde, Mathieu Vinken, Janette Turner, Thomas Steger-Hartmann
Published in: NAM Journal, 2025, ISSN 3050-6204
Publisher: Elsevier BV
DOI: 10.1016/J.NAMJNL.2025.100065

Mapping out strategies to further develop human-relevant, new approach methodology (NAM)-based developmental neurotoxicity (DNT) testing

Published in: ALTEX, 2025, ISSN 1868-596X
Publisher: ALTEX Edition
DOI: 10.14573/ALTEX.2501091

Virtual control groups in non-clinical toxicology – A replicability challenge.

Author(s): Steger-Hartmann T, Duchateau-Nguyen G, Bringezu F, Onidi M, Stirn M.
Published in: ALTEX, 2025, ISSN 1868-8551
Publisher: ALTEX
DOI: 10.14573/ALTEX.2503061

Integrative Data Science in Drug Safety Research: Experiences, Challenges, and Perspectives

Author(s): Ferran Sanz
Published in: Annual Review of Biomedical Data Science, Issue 8, 2025, ISSN 2574-3414
Publisher: Annual Reviews
DOI: 10.1146/ANNUREV-BIODATASCI-103123-095506

The need for epigenotoxicity testing

Published in: ALTEX, 2025, ISSN 1868-596X
Publisher: ALTEX Edition
DOI: 10.14573/ALTEX.2509281

The long way from raw data to NAM-based information: Overview on data layers and processing steps

Published in: ALTEX, Issue 42, 2025, ISSN 1868-596X
Publisher: ALTEX Edition
DOI: 10.14573/ALTEX.2412171

IHI VICT3R: Developing and Implementing Virtual Control Groups to Reduce Animal Use in Toxicology Research

Author(s): Thomas Steger-Hartmann, Ferran Sanz, Frank Bringezu, Inari Soininen
Published in: Toxicologic Pathology, 2025, ISSN 0192-6233
Publisher: SAGE Publications
DOI: 10.1177/01926233241303906

Mapping out strategies to further develop human-relevant, new approach methodology (NAM)-based developmental neurotoxicity (DNT) testing

Published in: ALTEX, 2025, ISSN 1868-596X
Publisher: ALTEX Edition
DOI: 10.14573/ALTEX.2501091

Leveraging biomarkers and translational medicine for preclinical safety - Lessons for advancing the validation of alternatives to animal testing

Published in: ALTEX, Issue 41, 2024, ISSN 1868-596X
Publisher: ALTEX Edition
DOI: 10.14573/altex.2410011