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TOXIcology & BEE COGnition : Uncovering the Impacts of Pesticides on Honey Bee Cognition

Project description

Impact of pesticides on honeybees

Honeybees play a role in pollination and exhibit complex learning processes essential for their foraging success. However, pesticide exposure can adversely affect their health and cognitive abilities. Supported by the Marie Skłodowska-Curie Actions programme, the TOXIBEECOG project will explore how exposure to neonicotinoids and sulfoxamine influences honeybee performance across three learning tasks with varying cognitive complexities: developmental learning (DL), reinforcement learning (RL), and negative patterning learning (NPL). DL involves simple associative learning, RL requires flexibility in the face of transient ambiguity, and NPL deals with constant stimulus ambiguity. The project aims to uncover the impact of pesticides on higher-order problem-solving skills and the neural mechanisms that underlie these cognitive changes.

Objective

Honey bees play a key role in diverse ecosystems due to their pollination services. This activity depends on the capacity to learn and memorize floral olfactory and visual cues, thus bees are not only able of simple associative learning but also master higher-order forms of learning. Reversal learning (RL) and Negative Patterning Learning (NPL) help bees to effectively exploit complex environments. Foraging leads to pesticidal exposure, contributing to the concerning decline of bee health. Several studies revealed the adverse effects of pesticides on bee health, but their impact on higher-order cognition is still unaddressed. Focusing on this vital form of behavioural plasticity is important as it could reveal pesticide impairments at unsuspected low doses, as compared to simpler and more robust learning tasks (e.g. Differential Learning, DL). Thus, it is relevant and timely to explore the impact of pesticides on higher-order cognition in bees, focusing on both classic (neonicotinoid) and newer (sulfoxamine) common insecticides. Here, we aim to investigate the impact of field-realistic exposure to a neonicotinoid and a sulfoxamine on three ecologically relevant learning tasks of varying cognitive complexity (DL, RL, NPL). While DL is a case of simple associative learning, RL involves transient stimulus ambiguity and requires learning flexibility; NPL is a case of non elemental learning as stimulus ambiguity is constantly present during the learning task. These problems will be studied in the olfactory domain, using olfactory conditioning, and in the visual domain, using a virtual reality approach. These protocols will be combined with various forms of pesticide exposure. We will determine how pesticides affect higher-order problem-solving in bees and will provide insights into the underlying neural mechanisms of pesticide effect on learning and memory. Our project represents an innovative initiative aiming at bridging the gap between cognition and ecotoxicology.

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

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(opens in new window) HORIZON-MSCA-2024-PF-01

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Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 226 420,56
Total cost

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