Obiettivo Optimal plant growth requires the orchestration of carbon metabolism over the day-night cycle, to avoid periods of starvation at night. Metabolism and growth at night are fueled by carbohydrates released by degradation of starch, synthesised from photosynthesis in the preceding day. Starch synthesis and degradation are regulated such that starch reserves are almost but not quite exhausted at the end of the night, in both long and short nights. We have recently found that this robust regulation is a function of the circadian clock, an endogenous timer that allows plants to anticipate and prepare for daily changes in their environment, and a paradigm for Systems Biology. The clock controls the rate of starch degradation at night, so that reserves last until the anticipated dawn. Starvation and growth arrest are avoided. This important discovery opens the way to new levels of understanding of the control of plant growth and productivity. TiMet assembles world leaders in experimental and theoretical plant Systems Biology to understand the regulatory interactions between the clock gene circuit and metabolism, and their emergent effects on growth and productivity. In addition to starch metabolism, we will study isoprenoid synthesis, an essential metabolic process linking starch metabolism to growth and development. Jointly-conducted experiments will use responses to day-length and light-quality regimes that perturb clock function, and a large set of mutants deficient in clock or central metabolic functions. High throughput technologies will enable study of transcriptional, post-transcriptional, translational and post-translational events, providing a depth of analysis hitherto unattained for either the clock or metabolism in plants. Innovative data mining and modelling platforms will underpin new, mechanistic models of each subsystem, will integrate them for the first time, and test the emergent effects of this dynamic system on plant growth rate and productivity. Campo scientifico natural sciencescomputer and information sciencesdata sciencedata miningsocial scienceseconomics and businesseconomicsproduction economicsproductivitynatural sciencesbiological sciencesbiochemistrybiomoleculescarbohydratesnatural sciencesbiological sciencesbotany Programma(i) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Argomento(i) KBBE-2009-1-1-01 - Integration of tools to support a system-based understanding of complex biological processes Invito a presentare proposte FP7-KBBE-2009-3 Vedi altri progetti per questo bando Meccanismo di finanziamento CP-IP - Large-scale integrating project Coordinatore THE UNIVERSITY OF EDINBURGH Contributo UE € 1 039 394,00 Indirizzo OLD COLLEGE, SOUTH BRIDGE EH8 9YL Edinburgh Regno Unito Mostra sulla mappa Regione Scotland Eastern Scotland Edinburgh Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Angela Noble (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (8) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto JOHN INNES CENTRE Regno Unito Contributo UE € 599 000,00 Indirizzo NORWICH RESEARCH PARK COLNEY NR4 7UH Norwich Mostra sulla mappa Regione East of England East Anglia Breckland and South Norfolk Tipo di attività Research Organisations Contatto amministrativo Mary Anderson (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Svizzera Contributo UE € 1 639 208,00 Indirizzo Raemistrasse 101 8092 Zuerich Mostra sulla mappa Regione Schweiz/Suisse/Svizzera Zürich Zürich Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Wilhelm Gruissem (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Germania Contributo UE € 1 459 000,00 Indirizzo HOFGARTENSTRASSE 8 80539 Munchen Mostra sulla mappa Regione Bayern Oberbayern München, Kreisfreie Stadt Tipo di attività Research Organisations Contatto amministrativo Lothar Grube (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB Spagna Contributo UE € 508 250,00 Indirizzo PARC DE RECERCA DE L UAB CAMPUS UAB EDIFICI CRAG BELLATERRA 08193 Cerdanyola Del Valles Mostra sulla mappa Regione Este Cataluña Barcelona Tipo di attività Other Contatto amministrativo Lali Sanz (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato SCOTTISH CROP RESEARCH INSTITUTE Regno Unito Contributo UE € 4 739,98 Indirizzo Invergowrie DD2 5DA DUNDEE Mostra sulla mappa Tipo di attività Research Organisations Contatto amministrativo Neil Hattersley (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN Regno Unito Contributo UE € 303 647,00 Indirizzo KING'S COLLEGE REGENT WALK AB24 3FX ABERDEEN Mostra sulla mappa Regione Scotland North Eastern Scotland Aberdeen City and Aberdeenshire Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Elizabeth Rattray (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE JAMES HUTTON INSTITUTE Partecipazione conclusa Regno Unito Contributo UE € 3 577,82 Indirizzo ERROL ROAD INVERGOWRIE DD2 5DA Dundee Mostra sulla mappa Regione Scotland Eastern Scotland Perth & Kinross and Stirling Tipo di attività Research Organisations Contatto amministrativo Karen Robb (Mrs.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITY OF GLASGOW Regno Unito Contributo UE € 287 512,20 Indirizzo UNIVERSITY AVENUE G12 8QQ Glasgow Mostra sulla mappa Regione Scotland West Central Scotland Glasgow City Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Joe Galloway (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato