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Contenuto archiviato il 2024-06-18

Biobank Standardisation and Harmonisation for Research Excellence in the European Union

Obiettivo

Given contemporary understanding of the complexity of the causal architecture of common chronic diseases, the next stage of bioclinical scientific progress will depend critically on large-scale pooled analyses of high quality data from many biobanks and bioclinical studies. Such analyses will only be possible if we are able to harmonise and standardise the collection, storage, and management of data and bio-samples across biobanking studies. Recent consortium-based meta-analyses of genome-wide association studies (GWAS) have clearly demonstrated that it is possible to pool and analyse genomic data with broad indicators of disease status. But if health care science is to move quickly towards the exciting goals that have been envisaged for public health, clinical science, and personalised medicine a far greater challenge must now be overcome. That is, the standardization and harmonization of data and key measures of life-style, social circumstances and environment, as well as critical sub-components of the phenotypes associated with common complex diseases. This is the mission of BioSHaRE-EU.
BioSHaRE-EU will work hand-in-hand with BBMRI (Biobanking and Bio-molecular Resources Research Infrastructure) and P3G (Public Population Project in Genomics), to build directly on extensive precursor work in the field of harmonisation and standardisation. The project will deliver tools to harmonize phenotypes of complex diseases, as well as lifestyle and environmental factors. In addition, it provides statistical methods and biostatistical tools for meta-analysis of large scale studies. These tools and methods will be developed and implemented in five large partner-biobanks: HUNT, KORA, LifeGene, LifeLines, UK-biobank. BioSHaRE-EU will also implement these in additional disease consortia of clinical biobanks, and other population-based biobanks.

Campo scientifico

Programma(i)

Argomento(i)

Invito a presentare proposte

FP7-HEALTH-2010-single-stage
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Meccanismo di finanziamento

CP-IP - Large-scale integrating project

Coordinatore

ACADEMISCH ZIEKENHUIS GRONINGEN
Contributo UE
€ 3 011 795,20
Indirizzo
HANZEPLEIN 1
9713 GZ Groningen
Paesi Bassi

Mostra sulla mappa
Regione
Noord-Nederland Groningen Overig Groningen
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Ronald Stolk (Prof.)
Collegamenti
Costo totale
Nessun dato

Partecipanti (16)

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Ultimo aggiornamento: 5 Aprile 2023

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Permalink: https://cordis.europa.eu/project/id/261433/it

European Union, 2024