Skip to main content
Vai all'homepage della Commissione europea (si apre in una nuova finestra)
italiano italiano
CORDIS - Risultati della ricerca dell’UE
CORDIS
Contenuto archiviato il 2024-06-18

Experimental Radiotherapy for Malignant Brain Tumours

Obiettivo

The aim of my project is to test two novel experimental radiotherapies which potentially can improve the quality life in patients with malignant brain tumours or with multiple brain metastases. Both methods are being developed at international synchrotron facilities. One of the techniques, microbeam radiation therapy (MRT), is already being studied by several groups and my work is focused on the assessment of adverse effects like memory deficits and bystander effects. Concept and equipment for the second technique, pencilbeam radiotherapy, have only recently been developed at the ESRF in France. Our team will be the first to obtain biological data and assist in developing the technique to a point where a valid assessment can be made regarding its feasibility for therapeutic approach in human patients. All tests will be conducted in well-validated small animal models for an advanced, highly malignant primary brain tumour and for multiple brain metastases from a mamma carcinoma.
We will study the acute effects of the radiotherapy in short-term experiments as well as generate survival curves and behavioural data in long-term survivors. In order to document the efficacy of the experimental therapy we will also use a high-resolution synchrotron-based X-ray imaging technique, in which small groups of cells loaded with an X-ray opaque marker can be detected. The applicant for this project is one of the four patent holders for this method.
The Marie Curie Reintegration Grant would help me to establish my own work group in Freiburg, thereby combining my previous research experience with the interests of the Department of Stereotactic Neurosurgery and the Laboratory of Molecular Neurosurgery, where I have been working since September 2009. The project also integrates research facilities in three European countries (Germany, France and Italy) as well as a collaboration with a radiobiology team from McMaster University in Hamilton, Canada.

Argomento(i)

Gli inviti a presentare proposte sono suddivisi per argomenti. Un argomento definisce un’area o un tema specifico per il quale i candidati possono presentare proposte. La descrizione di un argomento comprende il suo ambito specifico e l’impatto previsto del progetto finanziato.

Invito a presentare proposte

Procedura per invitare i candidati a presentare proposte di progetti, con l’obiettivo di ricevere finanziamenti dall’UE.

FP7-PEOPLE-2010-RG
Vedi altri progetti per questo bando

Meccanismo di finanziamento

Meccanismo di finanziamento (o «Tipo di azione») all’interno di un programma con caratteristiche comuni. Specifica: l’ambito di ciò che viene finanziato; il tasso di rimborso; i criteri di valutazione specifici per qualificarsi per il finanziamento; l’uso di forme semplificate di costi come gli importi forfettari.

MC-IRG - International Re-integration Grants (IRG)

Coordinatore

UNIVERSITAETSKLINIKUM FREIBURG
Contributo UE
€ 100 000,00
Indirizzo
HUGSTETTER STRASSE 49
79106 Freiburg
Germania

Mostra sulla mappa

Regione
Baden-Württemberg Freiburg Freiburg im Breisgau, Stadtkreis
Tipo di attività
Higher or Secondary Education Establishments
Collegamenti
Costo totale

I costi totali sostenuti dall’organizzazione per partecipare al progetto, compresi i costi diretti e indiretti. Questo importo è un sottoinsieme del bilancio complessivo del progetto.

Nessun dato
Il mio fascicolo 0 0