The target of this Transfer of Knowledge proposal is the elucidation of molecular mechanisms and biological activities at the sub-cellular level by using non-linear microscopy (Two Photon Excitation Fluorescence, Second Harmonic Generation) with femtosecond laser pulses for the excitation. The investigation of in vivo sub-cellular activities, by means of an imaging technique, can provide valuable and unique information related to fundamental biological problems, leading to the development of innovative methodologies for the early diagnosis and treatment of several diseases.
The interdisciplinary proposed project is related to the scientific areas of physics, biology and medicine. The contribution from several experienced external researchers, from the fields of non-linear laser physics, biophysics, cell biology and photodynamic therapy is essential for the successful realization of the proposed project. The high quality infrastructure and manpower of IESL-FORTH (host organization) ensures the excellence in absorbing the transferred knowledge that will significantly increase the research quality, the overall capabilities and the competitiveness of the host organization worldwide.
Aufforderung zur Vorschlagseinreichung
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