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Microfluidic assay for rapid multiplexed detection of bacterial urinary tract infections

Ziel

We propose to develop a microfluidic chip-sized assay for low-cost, sensitive, rapid, and multiplexed detection of bacteria in urine. We aim to reduce bacterial diagnostic time from the current standard of 1-3 days to several minutes. The device will have application to both conventional clinical microbiology laboratories and point-of-care settings, and will eliminate dependence on highly trained operators. We propose to use isotachophoresis (ITP) to extract and concentrate the bacterial signature 16S ribosomal RNA directly from urine samples, and detect and quantify its presence using a set of complementary fluorescent probes (molecular beacons) on a low-cost microfluidic chip.

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2011-CIG
Andere Projekte für diesen Aufruf anzeigen

Koordinator

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
EU-Beitrag
€ 100 000,00
Adresse
SENATE BUILDING TECHNION CITY
32000 Haifa
Israel

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Mark Davison (Mr.)
Links
Gesamtkosten
Keine Daten