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Design of MYB specific inhibitors

Obiettivo

During my ERC starting grant project, my lab has identified small molecule inhibitors that inhibit the proliferation of MYB-dependent leukemia cell lines. In this proof of concept project, we aim to investigate the potential of these compounds to be further developed as anti-cancer agents. We will determine their potential to inhibit the proliferation breast cancer and colon cancer cell lines and possible additional activity against other solid tumors. In addition, we will investigate the IP landscape and possibilities to improve the chemical properties. These pre-clinical data should provide the basis for the further development of these MYB inhibitors as anti-cancer agents.

Invito a presentare proposte

ERC-2011-PoC
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Coordinatore

VIB VZW
Indirizzo
Rijvisschestraat 120
9052 Zwijnaarde - gent
Belgio

Mostra sulla mappa

Regione
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Tipo di attività
Research Organisations
Contatto amministrativo
Rik Audenaert (Mr.)
Collegamenti
Contributo UE
Nessun dato

Beneficiari (1)