Obiettivo We propose to develop new chemometric and high-throughput analytical methods to assess the effects of environmental and climate changes on target biological systems which are representative of ecosystems. This project will combine powerful chemometric and analytical high-throughput methodologies with toxicological tests to examine the effects of environmental stressors (like chemical pollution) and of climate change (like temperature, water scarcity or food shortage), on genomic and metabonomic profiles of target biological systems. The complex nature of experimental data produced by high-throughput analytical techniques, such as DNA microarrays, hyphenated chromatography-mass spectrometry or multi-dimensional nuclear magnetic resonance spectroscopy, requires powerful data analysis tools to extract, summarize and interpret the large amount of information that such megavariate data sets may contain. There is a need to improve and automate every step in the analysis of the data generated from genomic and metabonomic studies using new chemometric and multi- and megavariate tools. The main purpose of this project is to develop such tools. As a result of the whole study, a detailed report on the effects of global change and chemical pollution on the genomic and metabonomic profiles of a selected set of representative target biological systems will be delivered and used for global risk assessment. The information acquired, data sets and computer software will be stored in public data bases using modern data compression and data management technologies. And all the methodologies developed in the project will be published. Campo scientifico natural sciencescomputer and information sciencesdata sciencenatural sciencescomputer and information sciencessoftwarenatural sciencesearth and related environmental sciencesenvironmental sciencespollutionnatural sciencesearth and related environmental sciencesatmospheric sciencesclimatologyclimatic changesnatural sciencesphysical sciencesopticsspectroscopy Programma(i) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) ERC-AG-PE4 - ERC Advanced Grant - Physical and Analytical Chemical sciences Invito a presentare proposte ERC-2012-ADG_20120216 Vedi altri progetti per questo bando Meccanismo di finanziamento ERC-AG - ERC Advanced Grant Istituzione ospitante AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Contributo UE € 2 175 212,58 Indirizzo CALLE SERRANO 117 28006 Madrid Spagna Mostra sulla mappa Regione Comunidad de Madrid Comunidad de Madrid Madrid Tipo di attività Research Organisations Contatto amministrativo Guillermo Sanjuanbenito (Mr.) Ricercatore principale Roman Tauler Ferrer (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Beneficiari (2) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spagna Contributo UE € 2 175 212,58 Indirizzo CALLE SERRANO 117 28006 Madrid Mostra sulla mappa Regione Comunidad de Madrid Comunidad de Madrid Madrid Tipo di attività Research Organisations Contatto amministrativo Guillermo Sanjuanbenito (Mr.) Ricercatore principale Roman Tauler Ferrer (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITAT DE BARCELONA Spagna Contributo UE € 279 067,42 Indirizzo GRAN VIA DE LES CORTS CATALANES 585 08007 Barcelona Mostra sulla mappa Regione Este Cataluña Barcelona Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Xavier Gutierrez (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato