Objective
A growing awareness of the relationship between diet and health has led to an increasing demand for food products that are able to enhance health, as well as provide basic nutrition. Synbiotics are functional foods that combine probiotics (living microorganisms) and their substrates - prebiotics. Synbiotics demonstrate synergistic health benefits on the consumer. Synbiotics' mode of action is poorly understood. Even so, it is suggested that synbiotics have antimicrobial, anticarcinogenic, immunomodulatory, antidiarrheal, antiallergenic, and other activities. Therefore, scientific documentation is of major importance for the credibility of the synbiotic products. Glycans play an important part in human nutrition; these include glycoconjugate molecules that are part of food ingredients and secreted glycans from microorganisms in food fermentation.
The issue of glycan analysis technology is repeatedly mentioned as key to the development of safer and better food. As the new head of biochemistry in NutriCognia, I will combine the company technology with the expertise I acquired in the USA to make use of synbiotics' glycan composition as a scientific tool for the characterization and monitoring of synbiotic aspects. Our approach to glycan analysis is based on lectin glycan interactions: glycoanalysis is performed by binding the intact glycoprotein to a lectin array (CarboDeep) and identification by specifically labelled lectin probes. CarboDeep presents a unique approach, that enables efficient, precise, qualitative, and quantitative methods for the study of synbiotics.
We propose to:
(1) optimise CarboDeep technology for the synbiotics field;
(2) develop synbiotic glyco-fingerprinting application, using the synbiotics' glycans biochip; and
(3) develop a biochip with higher specificity for synbiotics' glycans.
The proposed studies will provide a reliable scientific/technological tool for synbiotics analysis and afford a new insight of the synbiotics properties.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences chemical sciences polymer sciences
- medical and health sciences health sciences nutrition
- natural sciences biological sciences biochemistry biomolecules carbohydrates
- engineering and technology industrial biotechnology bioprocessing technologies fermentation
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-12
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IRG - Marie Curie actions-International re-integration grants
Coordinator
2230 ASHDOD
Israel
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.