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Electromagnetic detection of neural activity at cellular resolution

Projektbeschreibung


FET Proactive: Neuro-Bio-Inspired Systems (NBIS)

The main goal of the project is to develop a new generation of neuroscience tools for electromagnetic measurement and spectroscopy at the neuron level.Spin electronics offers nowadays the possibility to create very sensitive, micrometer-scale magnetic field detectors. Here, we propose to exploit this technological advance to create novel tools for probing neuronal magnetic fields at the cellular level. The first goal of the project will be to develop the magnetic equivalent of an electrode, a 'magnetrode', sensitive enough to detect the very small magnetic fields induced by the ionic currents flowing within electrically active neurons, and small enough to probe a limited number of cells. We will adapt magnetrodes also for local nuclear magnetic resonance spectroscopy (MRS); thus, they could record both electromagnetic and chemical activity of neurons. In addition, means for local electric or magnetic stimulation could be integrated in to a magnetrode. We will test magnetrodes in vitro and in vivo at various spatial scales, from brain areas down to single neurons. In parallel, based on the measurements with magnetrodes, we will augment existing computational models and develop new ones to characterize the electromagnetic fields emitted by neurons and neuron assemblies. We will use these models to bridge from the activity of single neurons to macroscopic non-invasive measurements such as electroencephalography (EEG) and magnetoencephalography (MEG).This project shall pave the way towards "magnetophysiology", which enables investigating electric activity of neurons without disturbing the ionic flow and without physical contact to the cell. We will create new experimental and modeling tools for magnetic measurements and stimulation at neuron scale. The resulting techniques will be applicable in neurosciences, brain–computer interfacing and possibly in the treatment of certain brain diseases.The consortium is composed of 5 teams from 4 EU countries.

Wissenschaftliches Gebiet

Programm/Programme

Thema/Themen

Aufforderung zur Vorschlagseinreichung

FP7-ICT-2011-9
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Finanzierungsplan

CP - Collaborative project (generic)

Kontakt Koordinator

Myriam Pannetier-Lecoeur Dr

Koordinator

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
EU-Beitrag
€ 510 478,00
Adresse
RUE LEBLANC 25
75015 PARIS 15
Frankreich

Auf der Karte ansehen
Region
Ile-de-France Ile-de-France Paris
Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Jean-Christophe Coste (Mr.)
Links
Gesamtkosten
Keine Daten

Beteiligte (4)

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Letzte Aktualisierung: 2 August 2019

Mein Booklet

Permalink: https://cordis.europa.eu/project/id/600730/de

European Union, 2024