Objectif "Early detection of an incipient wound infection is a challenge for the attending physician , since its early diagnosis allows the timely initiation of treatment, thus reducing the severity of the disease . Currently, however, wound infection is not diagnosed until becoming already evident. As a consequence, the treatment of the patient is further complicated and more likely to have a negative outcome4. Often wounds are treated with antibiotics before even the infection appears, leading to overdoses and development of bacterial resistance to antibiotics.Considering that optimal efficiency is reached when a material serves multiple functions without compromise, consortium partners have discovered the means to convert wound dressings into a diagnostic tool capable to inform both patient and therapist about the wound status, thus directing towards the following therapeutic step. The proposed functional materials include a real time diagnostic reaction that positively influences the wound healing due to the timely intervention to treat infection or proteolytic stasis in the woundThe novel InFact technology will be translated into a low-cost, real-time diagnostic tool as a constituent part of a wound dressing material, i.e. the ""triple-P"" materials concept:- Protective - by a decoy substrate for destructive proteases- Predictive – providing a cumulative wound status signal to predict the infection transition- Proactive - changing the dressing according to a signal, rather than on a schedule base, will provide therapeutic response in time, and not too late.More specifically, the functional materials (e.g. absorbent fibres and hydrocolloid pads) will incorporate immobilized substrates for three enzymes: myeloperoxidase, lysozyme and elastase. Upon infection, these enzymatic activities are highly elevated in wound fluids, and can be detected by the color change of the functional materials, visible via a window in the dressing." Champ scientifique engineering and technologymaterials engineeringcolorsmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Programme(s) FP7-NMP - Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies Thème(s) NMP.2013.4.0-3 - From research to innovation: substantial steps forward in the industrial use of European intellectual assets, stimulating the use of newly developed materials and materials technologies by the industry Appel à propositions FP7-NMP-2013-SME-7 Voir d’autres projets de cet appel Régime de financement CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinateur UNIVERSITAET FUER BODENKULTUR WIEN Contribution de l’UE € 661 811,00 Adresse GREGOR MENDEL STRASSE 33 1180 Wien Autriche Voir sur la carte Région Ostösterreich Wien Wien Type d’activité Higher or Secondary Education Establishments Contact administratif Georg Guebitz (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Participants (10) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire STICHTING MEDISCH SPECTRUM TWENTE Pays-Bas Contribution de l’UE € 293 125,00 Adresse HAAKSBERGERSTRAAT 55 7513 ER Enschede Voir sur la carte Région Oost-Nederland Overijssel Twente Type d’activité Other Contact administratif Job Van Der Palen (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée DI DR ANDREAS PAAR KG Autriche Contribution de l’UE € 381 980,00 Adresse LEECHGASSE 55/8 8010 GRAZ Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Andreas Paar (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée BAR ILAN UNIVERSITY Israël Contribution de l’UE € 392 320,00 Adresse BAR ILAN UNIVERSITY CAMPUS 52900 Ramat Gan Voir sur la carte Type d’activité Higher or Secondary Education Establishments Contact administratif Estelle Waise (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée DAVO STAR IMPEX SRL Roumanie Contribution de l’UE € 307 760,00 Adresse STR VALEA OTULUI 77-79 SECTOR 6 PARTER S1 S2 ETAJ 1 S3 061977 Bucuresti Voir sur la carte Région Macroregiunea Trei Bucureşti-Ilfov Bucureşti Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Daniela Anton (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée UNIVERSITAT POLITECNICA DE CATALUNYA Espagne Contribution de l’UE € 464 231,00 Adresse CALLE JORDI GIRONA 31 08034 Barcelona Voir sur la carte Région Este Cataluña Barcelona Type d’activité Higher or Secondary Education Establishments Contact administratif Mercedes Torrellas (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée ASSOCIACAO UNIVERSIDADE EMPRESA PARA DESENVOLVIMENTO TECMINHO Portugal Contribution de l’UE € 344 760,00 Adresse CAMPUS DE AZUREM UNIVERSIDADE DO MINHO 4800 058 Guimaraes Voir sur la carte Région Continente Norte Ave Type d’activité Other Contact administratif Fernando Ribeiro (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée SYNOVO GMBH Allemagne Contribution de l’UE € 489 480,00 Adresse Paul Ehrlich Str 15 72076 Tuebingen Voir sur la carte Région Baden-Württemberg Tübingen Tübingen, Landkreis Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Michael Burnet (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée CONVATEC LIMITED Royaume-Uni Contribution de l’UE € 497 380,00 Adresse GDC FIRST AVENUE - DEESIDE INDUSTRIAL PARK CH5 2NU DEESIDE FLINTSHIRE Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Philip Bowler (Mr.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO Pays-Bas Contribution de l’UE € 306 046,00 Adresse ANNA VAN BUERENPLEIN 1 2595 DA Den Haag Voir sur la carte Région West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage Type d’activité Research Organisations Contact administratif Herman Lenting (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée OSM-DAN LTD Israël Contribution de l’UE € 199 080,00 Adresse 19 PRO NEEMAN YUVAL ST 7608665 Rehovot Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Pnina Dan (Dr.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée