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Brain Imaging Return to Health

Objectif

Extended lifespan is a new and permanent feature of human life globally. The demographic for population growth of persons over 60 years is predicted to expand by 70% and 400% respectively in developed and less developed regions during the coming decades. Ageing, is accompanied by cognitive decline and greater risk of depression and anxiety. Major drug companies have recently cutback significantly on development of drugs against brain disorders due to lack of new avenues of research. Thus the responsibility falls on academic labs to make breakthroughs to improve brain health.
This consortium gathers experts on molecular mechanisms of age-associated pathologies including depressive disorders and anxiety, and neurodegeneration. Specifically, they focus on identification of stress-regulated molecules provoking neuronal death and hindering neurogenesis, and monitoring the consequences of these processes in human brain.
The groups combine biological and medical imaging techniques with behavioral studies and proteomics to define molecular mechanisms of ageing and neurogenesis. Using biotechnology, they will create new tools to isolate neurogenic cells from aged brain, thus aiding research strategies an early stage. Four leading imaging infrastructures from across Europe selected from the ESFRI Eurobioimaging Proof-of Concept list have been selected as partners to facilitate this training and research program. Confocal and high-content imaging is used to define ageing pathways, proteomics and genomics to visualize effectors of pathological ageing, transgenic mice to study neurogenesis and MRI/MRS to identify and localize new depression-related parameters in select patient populations. This multi-faceted approach aims to (i) identify druggable targets and identify reagents to interfere with pathways contributing to depression and anxiety, and (ii) produce novel tools to image depression-associated events in brain, facilitating earlier diagnosis and intervention.

Appel à propositions

FP7-PEOPLE-2013-ITN
Voir d’autres projets de cet appel

Régime de financement

MC-ITN - Networks for Initial Training (ITN)

Coordinateur

ABO AKADEMI
Adresse
Domkyrkotorget 3
20500 Abo
Finlande
Type d’activité
Higher or Secondary Education Establishments
Contribution de l’UE
€ 1 113 376,44
Contact administratif
Siv Holmgren (Ms.)

Participants (9)

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Irlande
Contribution de l’UE
€ 731 116,88
Adresse
College Green
2 Dublin
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Deirdre Savage (Ms.)
ITA-SUOMEN YLIOPISTO

Participation terminée

Finlande
Contribution de l’UE
€ 164 779,01
Adresse
Yliopistonranta 1 E
70211 Kuopio
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Hannele Juvaste (Dr.)
MAX IV Laboratory, Lund University
Suède
Contribution de l’UE
€ 818 275,48
Adresse
Paradisgatan 5C
22100 Lund
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Marianne Olsson (Prof.)
LEIBNIZ-INSTITUT FUER NEUROBIOLOGIE
Allemagne
Contribution de l’UE
€ 201 800,72
Adresse
Brenneckestrasse 6
39118 Magdeburg
Type d’activité
Research Organisations
Contact administratif
Thekla Thiel (Ms.)
IMMUNOVIA AB
Suède
Contribution de l’UE
€ 259 925,16
Adresse
Scheelevagen 2 Medicon Village
223 81 Lund
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Carl Borrebaeck (Prof.)
ADVANCED PRACTICAL DIAGNOSTICS
Belgique
Contribution de l’UE
€ 230 340
Adresse
Raadsherenstraat 3
2300 Turnhout
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Aye Mu Myint (Dr.)
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
Contribution de l’UE
€ 307 056,64
Adresse
University Park
NG7 2RD Nottingham
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Paul Cartledge (Mr.)
BGI EUROPE INSTITUTE FOND

Participation terminée

Danemark
Contribution de l’UE
€ 63 239,88
Adresse
Ole Maaloes Vej 3
2200 Kobenhavn N
Type d’activité
Other
Contact administratif
Jue Wang (Mrs.)
TURUN YLIOPISTO
Finlande
Contribution de l’UE
€ 324 399,79
Adresse
Yliopistonmaki
20014 Turku
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Mari Riipinen (Dr.)