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Brain Imaging Return to Health

Cel

Extended lifespan is a new and permanent feature of human life globally. The demographic for population growth of persons over 60 years is predicted to expand by 70% and 400% respectively in developed and less developed regions during the coming decades. Ageing, is accompanied by cognitive decline and greater risk of depression and anxiety. Major drug companies have recently cutback significantly on development of drugs against brain disorders due to lack of new avenues of research. Thus the responsibility falls on academic labs to make breakthroughs to improve brain health.
This consortium gathers experts on molecular mechanisms of age-associated pathologies including depressive disorders and anxiety, and neurodegeneration. Specifically, they focus on identification of stress-regulated molecules provoking neuronal death and hindering neurogenesis, and monitoring the consequences of these processes in human brain.
The groups combine biological and medical imaging techniques with behavioral studies and proteomics to define molecular mechanisms of ageing and neurogenesis. Using biotechnology, they will create new tools to isolate neurogenic cells from aged brain, thus aiding research strategies an early stage. Four leading imaging infrastructures from across Europe selected from the ESFRI Eurobioimaging Proof-of Concept list have been selected as partners to facilitate this training and research program. Confocal and high-content imaging is used to define ageing pathways, proteomics and genomics to visualize effectors of pathological ageing, transgenic mice to study neurogenesis and MRI/MRS to identify and localize new depression-related parameters in select patient populations. This multi-faceted approach aims to (i) identify druggable targets and identify reagents to interfere with pathways contributing to depression and anxiety, and (ii) produce novel tools to image depression-associated events in brain, facilitating earlier diagnosis and intervention.

Zaproszenie do składania wniosków

FP7-PEOPLE-2013-ITN
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Koordynator

ABO AKADEMI
Adres
Domkyrkotorget 3
20500 Abo
Finlandia

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Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Gundel Westerholm (Ms.)
Wkład UE
€ 1 113 376,44

Uczestnicy (9)

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Irlandia
Wkład UE
€ 731 116,88
Adres
College Green Trinity College
D02 CX56 Dublin 2

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Higher or Secondary Education Establishments
Kontakt administracyjny
Deirdre Savage (Ms.)
ITA-SUOMEN YLIOPISTO

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Finlandia
Wkład UE
€ 164 779,01
Adres
Yliopistonranta 1 E
70211 Kuopio
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Higher or Secondary Education Establishments
Kontakt administracyjny
Hannele Juvaste (Dr.)
LUNDS UNIVERSITET
Szwecja
Wkład UE
€ 818 275,48
Adres
Paradisgatan 5c
22100 Lund

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Higher or Secondary Education Establishments
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Marianne Olsson (Prof.)
LEIBNIZ-INSTITUT FUER NEUROBIOLOGIE
Niemcy
Wkład UE
€ 201 800,72
Adres
Brenneckestrasse 6
39118 Magdeburg

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Research Organisations
Kontakt administracyjny
Thekla Thiel (Ms.)
IMMUNOVIA AB
Szwecja
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€ 259 925,16
Adres
Scheelevagen 2 Medicon Village
223 81 Lund

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Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt administracyjny
Carl Borrebaeck (Prof.)
ADVANCED PRACTICAL DIAGNOSTICS
Belgia
Wkład UE
€ 230 340
Adres
Raadsherenstraat 3
2300 Turnhout

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Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt administracyjny
Aye Mu Myint (Dr.)
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
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€ 307 056,64
Adres
University Park
NG7 2RD Nottingham

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Higher or Secondary Education Establishments
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Paul Cartledge (Mr.)
BGI EUROPE INSTITUTE FOND

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Dania
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€ 63 239,88
Adres
Ole Maaloes Vej 3
2200 Kobenhavn N
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Other
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Jue Wang (Mrs.)
TURUN YLIOPISTO
Finlandia
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€ 324 399,79
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Yliopistonmaki
20014 Turku

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Higher or Secondary Education Establishments
Kontakt administracyjny
Mari Riipinen (Dr.)