Point-of-care microfluidic device for quantification of chemotherapeutic drugs in small body fluid samples by highly selective nanoparticle extraction and liquid crystal detection

Informazioni relative al progetto

DiaChemo

ID dell’accordo di sovvenzione: 633635

DOI 10.3030/633635

Progetto chiuso

Data della firma CE 13 Aprile 2015

Data di avvio 1 Maggio 2015

Data di completamento 31 Ottobre 2020

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale € 5 240 708,13

Contributo UE € 4 654 333,00

Coordinato da

ENTE OSPEDALIERO SAVERIO DE BELLIS IRCCS
Italy

Risultati finali

Websites, patent fillings, videos etc. (1)

Project Website

Design and maintenance of the project website as an important dissemination tool.

Pubblicazioni

Peer reviewed articles (9)

Microfluidics of binary liquid mixtures with temperature-dependent miscibility

Autori: Maximiliano J. Fornerod, Esther Amstad, Stefan Guldin
Pubblicato in: Molecular Systems Design & Engineering, Numero 5/1, 2020, Pagina/e 358-365, ISSN 2058-9689
Editore: Royal Society of Chemistry
DOI: 10.1039/c9me00127a

pH-Mediated molecular differentiation for fluorimetric quantification of chemotherapeutic drugs in human plasma

Autori: Luis A. Serrano; Ye Yang; Elisa Salvati; Francesco Stellacci; Silke Krol; Stefan Guldin
Pubblicato in: Chemical Communications , 54 (12) pp. 1485-1488. (2018), Numero 1, 2017, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.26434/chemrxiv.5662462.v1

A new high-performance liquid chromatography-tandem mass spectrometry method for the determination of paclitaxel and 6α-hydroxy-paclitaxel in human plasma: Development, validation and application in a clinical pharmacokinetic study

Autori: Bianca Posocco, Mauro Buzzo, Andrea Follegot, Luciana Giodini, Roberto Sorio, Elena Marangon, Giuseppe Toffoli
Pubblicato in: PLOS ONE, Numero 13/2, 2018, Pagina/e e0193500, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0193500

pH-Mediated molecular differentiation for fluorimetric quantification of chemotherapeutic drugs in human plasma

Autori: Luis A. Serrano, Ye Yang, Elisa Salvati, Francesco Stellacci, Silke Krol, Stefan Guldin
Pubblicato in: Chemical Communications, Numero 54/12, 2018, Pagina/e 1485-1488, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/c7cc07668a

A Toolkit to Quantify Target Compounds in Thin-Layer-Chromatography Experiments

Autori: Niamh Mac Fhionnlaoich, Stuart Ibsen, Luis A. Serrano, Alaric Taylor, Runzhang Qi, Stefan Guldin
Pubblicato in: Journal of Chemical Education, Numero 95/12, 2018, Pagina/e 2191-2196, ISSN 0021-9584
Editore: American Chemical Society
DOI: 10.1021/acs.jchemed.8b00144

A Versatile AuNP Synthetic Platform for Decoupled Control of Size and Surface Composition

Autori: Ye Yang, Luis A. Serrano, Stefan Guldin
Pubblicato in: Langmuir, Numero 34/23, 2018, Pagina/e 6820-6826, ISSN 0743-7463
Editore: American Chemical Society
DOI: 10.1021/acs.langmuir.8b00353

Microfluidics of binary liquid mixtures with temperature-dependent miscibility

Autori: Fornerod, Maximiliano J.; Amstad, Esther; Guldin, Stefan
Pubblicato in: Molecular Systems Design & Engineering (2019) (In press)., Numero 95/12, 2019, Pagina/e N/A, ISSN 1908-8922
Editore: Royal Society of Chemistry
DOI: 10.26434/chemrxiv.6970301.v2

Probing the interaction of nanoparticles with small molecules in real time via quartz crystal microbalance monitoring

Autori: Ye Yang, Guillaume Poss, Yini Weng, Runzhang Qi, Hanrui Zheng, Nikolaos Nianias, Euan R. Kay, Stefan Guldin
Pubblicato in: Nanoscale, Numero 11/23, 2019, Pagina/e 11107-11113, ISSN 2040-3364
Editore: Royal Society of Chemistry
DOI: 10.1039/c9nr03162f

Phase behaviour and applications of a binary liquid mixture of methanol and a thermotropic liquid crystal

Autori: Luis A. Serrano, Maximiliano J. Fornerod, Ye Yang, Simon Gaisford, Francesco Stellacci, Stefan Guldin
Pubblicato in: Soft Matter, Numero 14/22, 2018, Pagina/e 4615-4620, ISSN 1744-683X
Editore: Royal Society of Chemistry
DOI: 10.1039/c8sm00327k

Book chapters (1)

Noble metal nanoparticles with anisotropy in shape and surface functionality for biomedical applications

Autori: Domenico Marson, Ye Yang, Stefan Guldin, Paola Posocco
Pubblicato in: Anisotropic Particle Assemblies, 2018, Pagina/e 313-333, ISBN 9780-128040690
Editore: Elsevier
DOI: 10.1016/b978-0-12-804069-0.00011-3

Non-peer reviewed articles (1)

Reversible microscale assembly of nanoparticles driven by the phase transition of a thermotropic liquid crystal

Autori: Niamh Mac Fhionnlaoich Stephen Schrettl Nicholas B. Tito Ye Yang Malavika Nair Luis A. Serrano Kellen Harkness Paulo Jacob Silva Holger Frauenrath Francesco Stellacci Stefan Guldin
Pubblicato in: ChemRXIV, 2018, ISSN 0306-0012
Editore: Royal Society of Chemistry