Next Generation Label-free Chemical Nanoscopy for Biomedical Applications

Informazioni relative al progetto

NanoChemBioVision

ID dell’accordo di sovvenzione: 638258

DOI 10.3030/638258

Progetto chiuso

Data della firma CE 9 Marzo 2015

Data di avvio 1 Aprile 2015

Data di completamento 31 Marzo 2020

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 916 076,00

Contributo UE € 1 916 076,00

Coordinato da

UNIVERSITY OF SOUTHAMPTON
United Kingdom

Pubblicazioni

Peer reviewed articles (14)

Multimodal spectral focusing CARS and SFG microscopy with a tailored coherent continuum from a microstructured fiber

Autori: Krzysztof P. Herdzik, Konstantinos N. Bourdakos, Peter B. Johnson, Adam P. Lister, Aleksandra P. Pitera, Chun-yu Guo, Peter Horak, David J. Richardson, Jonathan H. V. Price, Sumeet Mahajan
Pubblicato in: Applied Physics B, Numero 126/5, 2020, ISSN 0946-2171
Editore: Springer Verlag
DOI: 10.1007/s00340-020-7406-6

Serum Raman spectroscopy as a diagnostic tool in patients with Huntington's disease

Autori: Anna Huefner, Wei-Li Kuan, Sarah L. Mason, Sumeet Mahajan, Roger A. Barker
Pubblicato in: Chemical Science, Numero 11/2, 2020, Pagina/e 525-533, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/c9sc03711j

Live-imaging of Bioengineered Cartilage Tissue using Multimodal Non-linear Molecular Imaging

Autori: Catarina Costa Moura, Konstantinos N. Bourdakos, Rahul S. Tare, Richard O. C. Oreffo, Sumeet Mahajan
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-41466-w

Conformational Evolution of Molecular Signatures during Amyloidogenic Protein Aggregation

Autori: George Devitt, William Rice, Anna Crisford, Iris Nandhakumar, Amrit Mudher, Sumeet Mahajan
Pubblicato in: ACS Chemical Neuroscience, Numero 10/11, 2019, Pagina/e 4593-4611, ISSN 1948-7193
Editore: American Chemical Society
DOI: 10.1021/acschemneuro.9b00451

Tracking adipogenic differentiation of skeletal stem cells by label-free chemically selective imaging

Autori: Justyna P. Smus, Catarina Costa Moura, Emma McMorrow, Rahul S. Tare, Richard O. C. Oreffo, Sumeet Mahajan
Pubblicato in: Chemical Science, Numero 6/12, 2015, Pagina/e 7089-7096, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/C5SC02168E

Raman spectroscopy and coherent anti-Stokes Raman scattering imaging: prospective tools for monitoring skeletal cells and skeletal regeneration

Autori: Catarina Costa Moura, Rahul S. Tare, Richard O. C. Oreffo, Sumeet Mahajan
Pubblicato in: Journal of The Royal Society Interface, Numero 13/118, 2016, Pagina/e 20160182, ISSN 1742-5689
Editore: The Royal Society
DOI: 10.1098/rsif.2016.0182

Characterization and Visualization of Vesicles in the Endo-Lysosomal Pathway with Surface-Enhanced Raman Spectroscopy and Chemometrics

Autori: Anna Huefner, Wei-Li Kuan, Karin H. Müller, Jeremy N. Skepper, Roger A. Barker, Sumeet Mahajan
Pubblicato in: ACS Nano, Numero 10/1, 2015, Pagina/e 307-316, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.5b04456

Tuning plasmons layer-by-layer for quantitative colloidal sensing with surface-enhanced Raman spectroscopy

Autori: William J. Anderson, Kamila Nowinska, Tanya Hutter, Sumeet Mahajan, Martin Fischlechner
Pubblicato in: Nanoscale, Numero 10/15, 2018, Pagina/e 7138-7146, ISSN 2040-3364
Editore: Royal Society of Chemistry
DOI: 10.1039/c7nr06656b

Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

Autori: Mark G Jones, Orestis G Andriotis, James JW Roberts, Kerry Lunn, Victoria J Tear, Lucy Cao, Kjetil Ask, David E Smart, Alessandra Bonfanti, Peter Johnson, Aiman Alzetani, Franco Conforti, Regan Doherty, Chester Y Lai, Benjamin Johnson, Konstantinos N Bourdakos, Sophie V Fletcher, Ben G Marshall, Sanjay Jogai, Christopher J Brereton, Serena J Chee, Christian H Ottensmeier, Patricia Sime, Jack Gauld
Pubblicato in: eLife, Numero 7, 2018, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/eLife.36354

Raman Spectroscopy: An Emerging Tool in Neurodegenerative Disease Research and Diagnosis

Autori: George Devitt, Kelly Howard, Amrit Mudher, Sumeet Mahajan
Pubblicato in: ACS Chemical Neuroscience, Numero 9/3, 2018, Pagina/e 404-420, ISSN 1948-7193
Editore: American Chemical Society
DOI: 10.1021/acschemneuro.7b00413

Optimising superoscillatory spots for far-field super-resolution imaging

Autori: Katrine S. Rogers, Konstantinos N. Bourdakos, Guang Hui Yuan, Sumeet Mahajan, Edward T. F. Rogers
Pubblicato in: Optics Express, Numero 26/7, 2018, Pagina/e 8095, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.26.008095

Quantitative temporal interrogation in 3D of bioengineered human cartilage using multimodal label-free imaging

Autori: Catarina Costa Moura, Stuart A. Lanham, Tual Monfort, Konstantinos N. Bourdakos, Rahul S. Tare, Richard O. C. Oreffo, Sumeet Mahajan
Pubblicato in: Integrative Biology, Numero 10/10, 2018, Pagina/e 635-645, ISSN 1757-9694
Editore: Royal Society of Chemistry
DOI: 10.1039/c8ib00050f

Hepatic Steatosis Accompanies Pulmonary Alveolar Proteinosis

Autori: Alan N. Hunt, Anagha Malur, Tual Monfort, Pavlos Lagoudakis, Sumeet Mahajan, Anthony D. Postle, Mary Jane Thomassen
Pubblicato in: American Journal of Respiratory Cell and Molecular Biology, Numero 57/4, 2017, Pagina/e 448-458, ISSN 1044-1549
Editore: American Lung Association
DOI: 10.1165/rcmb.2016-0242oc

Nanoparticles and intracellular applications of surface-enhanced Raman spectroscopy

Autori: Jack Taylor, Anna Huefner, Li Li, Jonathan Wingfield, Sumeet Mahajan
Pubblicato in: The Analyst, Numero 141/17, 2016, Pagina/e 5037-5055, ISSN 0003-2654
Editore: Royal Society of Chemistry
DOI: 10.1039/c6an01003b

Other (2)

Super-resolved polarisation-enhanced second harmonic generation for direct imaging of nanoscale changes in collagen architecture

Autori: Peter Johnson, Artemis Karvounis, H. Johnson Singh, Christopher J. Brereton, Konstantinos Bourdakos, Kerry Lunn, James JW Roberts, Donna E Davies, Otto L. Muskens, Mark G Jones, Sumeet Mahajan
Pubblicato in: 2020
Editore: Cold spring harbor laboratory
DOI: 10.1101/2020.02.07.934000

Label-free and Multimodal Second Harmonic Generation Light Sheet Microscopy

Autori: Niall Hanrahan, Simon I. R. Lane, Peter Johnson, Konstantinos Bourdakos, Christopher Brereton, Robert A. Ridley, Elizabeth R. Davies, Neveen A. Hosny, Gunnar Spickermann, Robert Forster, Graeme Malcolm, Donna Davies, Mark G. Jones, Sumeet Mahajan
Pubblicato in: 2020
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.09.07.284703