Organ-specific mechanisms of lymphatic vascular development and specialisation

Pubblicazioni

Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity

Autori: Yixin Wang, Yi Jin, Maarja Andaloussi Mäe, Yang Zhang, Henrik Ortsäter, Christer Betsholtz, Taija Mäkinen, Lars Jakobsson
Pubblicato in: Development, Numero 144/19, 2017, Pagina/e 3590-3601, ISSN 0950-1991
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dev.147967

Vascular heterogeneity and specialization in development and disease

Autori: Michael Potente, Taija Mäkinen
Pubblicato in: Nature Reviews Molecular Cell Biology, Numero 18/8, 2017, Pagina/e 477-494, ISSN 1471-0072
Editore: Nature Publishing Group
DOI: 10.1038/nrm.2017.36

Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms

Autori: Yan Zhang, Maria H. Ulvmar, Lukas Stanczuk, Ines Martinez-Corral, Maike Frye, Kari Alitalo, Taija Mäkinen
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-03692-0

Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program

Autori: Maike Frye, Andrea Taddei, Cathrin Dierkes, Ines Martinez-Corral, Matthew Fielden, Henrik Ortsäter, Jan Kazenwadel, Dinis P. Calado, Pia Ostergaard, Marjo Salminen, Liqun He, Natasha L. Harvey, Friedemann Kiefer, Taija Mäkinen
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-03959-6

Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels

Autori: Yang Zhang, Nina Daubel, Simon Stritt, Taija Mäkinen
Pubblicato in: Development, Numero 145/3, 2018, Pagina/e dev156745, ISSN 0950-1991
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dev.156745

Heterogeneity in the lymphatic vascular system and its origin

Autori: Maria H. Ulvmar, Taija Mäkinen
Pubblicato in: Cardiovascular Research, Numero 111/4, 2016, Pagina/e 310-321, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvw175

Pdgfrb-Cre targets lymphatic endothelial cells of both venous and non-venous origins

Autori: Maria H. Ulvmar, Ines Martinez-Corral, Lukas Stanczuk, Taija Mäkinen
Pubblicato in: genesis, Numero 54/6, 2016, Pagina/e 350-358, ISSN 1526-954X
Editore: John Wiley & Sons Inc.
DOI: 10.1002/dvg.22939

Vegfr3-CreER T2 mouse, a new genetic tool for targeting the lymphatic system

Autori: Ines Martinez-Corral, Lukas Stanczuk, Maike Frye, Maria Helena Ulvmar, Rodrigo Diéguez-Hurtado, David Olmeda, Taija Makinen, Sagrario Ortega
Pubblicato in: Angiogenesis, Numero 19/3, 2016, Pagina/e 433-445, ISSN 0969-6970
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10456-016-9505-x

Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreERT2 lines

Autori: A. Álvarez-Aznar, I. Martínez-Corral, N. Daubel, C. Betsholtz, T. Mäkinen, K. Gaengel
Pubblicato in: Transgenic Research, 2019, ISSN 0962-8819
Editore: Chapman & Hall
DOI: 10.1007/s11248-019-00177-8

Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation

Autori: Ines Martinez-Corral, Yan Zhang, Milena Petkova, Henrik Ortsäter, Sofie Sjöberg, Sandra D. Castillo, Pascal Brouillard, Louis Libbrecht, Dieter Saur, Mariona Graupera, Kari Alitalo, Laurence Boon, Miikka Vikkula, Taija Mäkinen
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-16496-y

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