Understanding and Designing Novel NanoPores

Publicaciones

Digital Sensing and Molecular Computation by an Enzyme-Free DNA Circuit

Autores: William E. Arter; Yuriy Yusim; Quentin Peter; Chris Taylor; David Klenerman; Ulrich F. Keyser; Tuomas P. J. Knowles
Publicado en: ACS Nano, Edición 3, 2020, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.17863/cam.56064

Optimizing Brownian escape rates by potential shaping

Autores: Marie Chupeau, Jannes Gladrow, Alexei Chepelianskii, Ulrich F. Keyser, Emmanuel Trizac
Publicado en: Proceedings of the National Academy of Sciences, Edición 117/3, 2020, Página(s) 1383-1388, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.1910677116

Electrical DNA Sequence Mapping Using Oligodeoxynucleotide Labels and Nanopores

Autores: Kaikai Chen, Felix Gularek, Boyao Liu, Elmar Weinhold, Ulrich F. Keyser
Publicado en: ACS Nano, Edición 15/2, 2021, Página(s) 2679-2685, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.0c07947

Experimental Measurement of Relative Path Probabilities and Stochastic Actions

Autores: Jannes Gladrow, Ulrich F. Keyser, R. Adhikari, Julian Kappler
Publicado en: Physical Review X, Edición 11/3, 2021, ISSN 2160-3308
Editor: American Physical Society
DOI: 10.1103/physrevx.11.031022

Nanopore-Based DNA Hard Drives for Rewritable and Secure Data Storage

Autores: Kaikai Chen, Jinbo Zhu, Filip Bošković, Ulrich F. Keyser
Publicado en: Nano Letters, Edición 20/5, 2020, Página(s) 3754-3760, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.0c00755

Single-cell microfluidics facilitates the rapid quantification of antibiotic accumulation in Gram-negative bacteria

Autores: Jehangir Cama, Margaritis Voliotis, Jeremy Metz, Ashley Smith, Jari Iannucci, Ulrich F. Keyser, Krasimira Tsaneva-Atanasova, Stefano Pagliara
Publicado en: Lab on a Chip, Edición 20/15, 2020, Página(s) 2765-2775, ISSN 1473-0197
Editor: Royal Society of Chemistry
DOI: 10.1039/d0lc00242a

Particle transport across a channel via an oscillating potential

Autores: Yizhou Tan, Jannes Gladrow, Ulrich F. Keyser, Leonardo Dagdug, Stefano Pagliara
Publicado en: Physical Review E, Edición 96/5, 2017, ISSN 2470-0045
Editor: American Physical Society
DOI: 10.1103/physreve.96.052401

Characterization of lipid composition and diffusivity in OLA generated vesicles

Autores: Michael Schaich, Diana Sobota, Hannah Sleath, Jehangir Cama, Ulrich F. Keyser
Publicado en: Biochimica et Biophysica Acta (BBA) - Biomembranes, Edición 1862/9, 2020, Página(s) 183359, ISSN 0005-2736
Editor: Elsevier BV
DOI: 10.1016/j.bbamem.2020.183359

Direct detection of molecular intermediates from first-passage times

Autores: Alice L. Thorneywork, Jannes Gladrow, Yujia Qing, Marc Rico-Pasto, Felix Ritort, Hagan Bayley, Anatoly B. Kolomeisky, Ulrich F. Keyser
Publicado en: Science Advances, Edición 6/18, 2020, Página(s) eaaz4642, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aaz4642

Switching Cytolytic Nanopores into Antimicrobial Fractal Ruptures by a Single Side Chain Mutation

Autores: Katharine Hammond, Flaviu Cipcigan, Kareem Al Nahas, Valeria Losasso, Helen Lewis, Jehangir Cama, Fausto Martelli, Patrick W. Simcock, Marcus Fletcher, Jascindra Ravi, Phillip J. Stansfeld, Stefano Pagliara, Bart W. Hoogenboom, Ulrich F. Keyser, Mark S. P. Sansom, Jason Crain, Maxim G. Ryadnov
Publicado en: ACS Nano, Edición 15/6, 2021, Página(s) 9679-9689, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.1c00218

Kinetics of Toehold-Mediated DNA Strand Displacement Depend on FeII4L4 Tetrahedron Concentration.

Autores: Jinbo Zhu; Filip Bošković; Bao-Nguyen T. Nguyen; Jonathan R. Nitschke; Ulrich F. Keyser
Publicado en: Nano Letters, Edición 4, 2021, ISSN 1530-6992
Editor: American Chemical Society
DOI: 10.17863/cam.63011

Cations Regulate Membrane Attachment and Functionality of DNA Nanostructures.

Autores: Morzy, Diana; Rubio-Sánchez, Roger; Joshi, Himanshu; Aksimentiev, Aleksei; Di Michele, Lorenzo; Keyser, Ulrich F
Publicado en: Journal of the American Chemical Society, Edición 3, 2021, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.17863/cam.68738

Large-Conductance Transmembrane Porin Made from DNA Origami

Autores: Kerstin Göpfrich, Chen-Yu Li, Maria Ricci, Satya Prathyusha Bhamidimarri, Jejoong Yoo, Bertalan Gyenes, Alexander Ohmann, Mathias Winterhalter, Aleksei Aksimentiev, Ulrich F. Keyser
Publicado en: ACS Nano, 2016, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.6b03759

Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores

Autores: Nicholas A. W. Bell, Ulrich F. Keyser
Publicado en: Nature Nanotechnology, Edición 11/7, 2016, Página(s) 645-651, ISSN 1748-3387
Editor: Nature Publishing Group
DOI: 10.1038/nnano.2016.50

Ion Channels Made from a Single Membrane-Spanning DNA Duplex

Autores: Kerstin Göpfrich, Chen-Yu Li, Iwona Mames, Satya Prathyusha Bhamidimarri, Maria Ricci, Jejoong Yoo, Adam Mames, Alexander Ohmann, Mathias Winterhalter, Eugen Stulz, Aleksei Aksimentiev, Ulrich F. Keyser
Publicado en: Nano Letters, Edición 16/7, 2016, Página(s) 4665-4669, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.6b02039

Extrinsic Cation Selectivity of 2D Membranes

Autores: Walker, MI; Ubych, K; Saraswat, V; Chalklen, EA; Braeuninger-Weimer, P; Caneva, S; Weatherup, RS; Hofmann, S; Keyser, UF
Publicado en: ACS Nano, Edición 3, 2017, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.17863/CAM.9055

Asymmetric dynamics of DNA entering and exiting a strongly confining nanopore

Autores: Nicholas A. W. Bell, Kaikai Chen, Sandip Ghosal, Maria Ricci, Ulrich F. Keyser
Publicado en: Nature Communications, Edición 8/1, 2017, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-017-00423-9

Correction to Ion Channels Made from a Single Membrane-Spanning DNA Duplex

Autores: Kerstin Göpfrich, Chen-Yu Li, Iwona Mames, Satya Prathyusha Bhamidimarri, Maria Ricci, Jejoong Yoo, Adam Mames, Alexander Ohmann, Mathias Winterhalter, Eugen Stulz, Aleksei Aksimentiev, Ulrich F. Keyser
Publicado en: Nano Letters, Edición 17/7, 2017, Página(s) 4548-4548, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.7b02430

Ionic Current-Based Mapping of Short Sequence Motifs in Single DNA Molecules Using Solid-State Nanopores

Autores: Kaikai Chen, Matyas Juhasz, Felix Gularek, Elmar Weinhold, Yu Tian, Ulrich F. Keyser, Nicholas A. W. Bell
Publicado en: Nano Letters, Edición 17/9, 2017, Página(s) 5199-5205, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.7b01009

Optical Voltage Sensing Using DNA Origami.

Autores: Hemmig, Elisa A; Fitzgerald, Clare; Maffeo, Christopher; Hecker, Lisa; Ochmann, Sarah E; Aksimentiev, Aleksei; Tinnefeld, Philip; Keyser, Ulrich Felix
Publicado en: Nano Letters, Edición 3, 2018, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.17863/CAM.22565

QuipuNet: Convolutional Neural Network for Single-Molecule Nanopore Sensing

Autores: Karolis Misiunas, Niklas Ermann, Ulrich F. Keyser
Publicado en: Nano Letters, Edición 18/6, 2018, Página(s) 4040-4045, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.8b01709

Tunable Anion-Selective Transport through Monolayer Graphene and Hexagonal Boron Nitride

Autores: Mustafa Caglar, Inese Silkina, Bertram T. Brown, Alice L. Thorneywork, Oliver J. Burton, Vitaliy Babenko, Stephen Matthew Gilbert, Alex Zettl, Stephan Hofmann, Ulrich F. Keyser
Publicado en: ACS Nano, 2020, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.9b08168

An Integrated Microfluidic Platform for Quantifying Drug Permeation across Biomimetic Vesicle Membranes

Autores: Michael Schaich, Jehangir Cama, Kareem Al Nahas, Diana Sobota, Hannah Sleath, Kevin Jahnke, Siddharth Deshpande, Cees Dekker, Ulrich F. Keyser
Publicado en: Molecular Pharmaceutics, Edición 16/6, 2019, Página(s) 2494-2501, ISSN 1543-8384
Editor: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.9b00086

A microfluidic platform for the characterisation of membrane active antimicrobials

Autores: K. Al Nahas, J. Cama, M. Schaich, K. Hammond, S. Deshpande, C. Dekker, M. G. Ryadnov, U. F. Keyser
Publicado en: Lab on a Chip, Edición 19/5, 2019, Página(s) 837-844, ISSN 1473-0197
Editor: Royal Society of Chemistry
DOI: 10.1039/c8lc00932e

Current Enhancement in Solid-State Nanopores Depends on Three-Dimensional DNA Structure

Autores: Vivian Wang, Niklas Ermann, Ulrich F. Keyser
Publicado en: Nano Letters, Edición 19/8, 2019, Página(s) 5661-5666, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.9b02219

Monitoring G-Quadruplex Formation with DNA Carriers and Solid-State Nanopores

Autores: Filip Bošković, Jinbo Zhu, Kaikai Chen, Ulrich F. Keyser
Publicado en: Nano Letters, Edición 19/11, 2019, Página(s) 7996-8001, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.9b03184

Multiplexed DNA Identification Using Site Specific dCas9 Barcodes and Nanopore Sensing

Autores: Nicole E. Weckman, Niklas Ermann, Richard Gutierrez, Kaikai Chen, James Graham, Ran Tivony, Andrew Heron, Ulrich F. Keyser
Publicado en: ACS Sensors, Edición 4/8, 2019, Página(s) 2065-2072, ISSN 2379-3694
Editor: American Chemcial Society
DOI: 10.1021/acssensors.9b00686

Cation dependent electroosmotic flow in glass nanopores

Autores: Jeffrey Mc Hugh, Kurt Andresen, Ulrich F. Keyser
Publicado en: Applied Physics Letters, Edición 115/11, 2019, Página(s) 113702, ISSN 0003-6951
Editor: American Institute of Physics
DOI: 10.1063/1.5116760

Nonlinear Electrophoresis of Highly Charged Nonpolarizable Particles

Autores: Soichiro Tottori, Karolis Misiunas, Ulrich F. Keyser, Douwe Jan Bonthuis
Publicado en: Physical Review Letters, Edición 123/1, 2019, ISSN 0031-9007
Editor: American Physical Society
DOI: 10.1103/PhysRevLett.123.014502

A synthetic enzyme built from DNA flips 107 lipids per second in biological membranes

Autores: Alexander Ohmann, Chen-Yu Li, Christopher Maffeo, Kareem Al Nahas, Kevin N. Baumann, Kerstin Göpfrich, Jejoong Yoo, Ulrich F. Keyser, Aleksei Aksimentiev
Publicado en: Nature Communications, Edición 9/1, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-04821-5

Density-Dependent Speed-up of Particle Transport in Channels

Autores: Karolis Misiunas, Ulrich F. Keyser
Publicado en: Physical Review Letters, Edición 122/21, 2019, ISSN 0031-9007
Editor: American Physical Society
DOI: 10.1103/PhysRevLett.122.214501

Promoting single-file DNA translocations through nanopores using electro-osmotic flow

Autores: Niklas Ermann, Nikita Hanikel, Vivian Wang, Kaikai Chen, Nicole E. Weckman, Ulrich F. Keyser
Publicado en: The Journal of Chemical Physics, Edición 149/16, 2018, Página(s) 163311, ISSN 0021-9606
Editor: American Institute of Physics
DOI: 10.1063/1.5031010

Specific Biosensing Using DNA Aptamers and Nanopores

Autores: Jinglin Kong, Jinbo Zhu, Kaikai Chen, Ulrich F. Keyser
Publicado en: Advanced Functional Materials, Edición 29/3, 2019, Página(s) 1807555, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201807555

Experimental evidence of symmetry breaking of transition-path times

Autores: J. Gladrow, M. Ribezzi-Crivellari, F. Ritort, U. F. Keyser
Publicado en: Nature Communications, Edición 10/1, 2019, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-07873-9

Digital Data Storage Using DNA Nanostructures and Solid-State Nanopores

Autores: Kaikai Chen, Jinglin Kong, Jinbo Zhu, Niklas Ermann, Paul Predki, Ulrich F. Keyser
Publicado en: Nano Letters, Edición 19/2, 2019, Página(s) 1210-1215, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.8b04715

Controlling aggregation of cholesterol-modified DNA nanostructures

Autores: Alexander Ohmann, Kerstin Göpfrich, Himanshu Joshi, Rebecca F Thompson, Diana Sobota, Neil A Ranson, Aleksei Aksimentiev, Ulrich F Keyser
Publicado en: Nucleic Acids Research, Edición 47/21, 2019, Página(s) 11441-11451, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkz914

Tailoring Interleaflet Lipid Transfer with a DNA-based Synthetic Enzyme

Autores: Diana Sobota, Himanshu Joshi, Alexander Ohmann, Aleksei Aksimentiev, Ulrich F. Keyser
Publicado en: Nano Letters, Edición 20/6, 2020, Página(s) 4306-4311, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.0c00990

Image Encoding Using Multi‐Level DNA Barcodes with Nanopore Readout

Autores: Jinbo Zhu; Niklas Ermann; Kaikai Chen; Ulrich F. Keyser
Publicado en: Crossref, Edición 2, 2021, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.17863/cam.71444

DNA Structural Barcode Copying and Random Access

Autores: Filip Bošković, Alexander Ohmann, Ulrich F. Keyser, Kaikai Chen
Publicado en: Small Structures, Edición 2/5, 2021, Página(s) 2000144, ISSN 2688-4062
Editor: Wiley-VCH GmbH
DOI: 10.1002/sstr.202000144

Single molecule based SNP detection using designed DNA carriers and solid-state nanopores

Autores: Kong, Jinglin; Zhu, Jinbo; Keyser, Ulrich F.
Publicado en: Chemical Communications, Edición 1, 2017, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.17863/cam.7988

Channel-length dependence of particle diffusivity in confinement

Autores: Soichiro Tottori, Karolis Misiunas, Vahe Tshitoyan, Ulrich F. Keyser
Publicado en: Soft Matter, Edición 17/20, 2021, Página(s) 5131-5136, ISSN 1744-683X
Editor: Royal Society of Chemistry
DOI: 10.1039/d1sm00289a

Direction- and Salt-Dependent Ionic Current Signatures for DNA Sensing with Asymmetric Nanopores

Autores: Kaikai Chen, Nicholas A.W. Bell, Jinglin Kong, Yu Tian, Ulrich F. Keyser
Publicado en: Biophysical Journal, Edición 112/4, 2017, Página(s) 674-682, ISSN 0006-3495
Editor: Biophysical Society
DOI: 10.1016/j.bpj.2016.12.033

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