Identification and functional characterization of mammalian enhancers and transcriptional co-factors during cellular signaling and cell fate transitions

Project Information

Enhancer ID

Grant agreement ID: 647320

DOI 10.3030/647320

Project closed

EC signature date 19 May 2015

Start date 1 September 2015

End date 31 January 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 999 906,00

EU contribution € 1 999 906,00

Coordinated by

FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH
Austria

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Other (1)

DeepSTARR predicts enhancer activity from DNA sequence and enables the de novo design of enhancers

Author(s): Bernardo P. de Almeida, Franziska Reiter, Michaela Pagani, Alexander Stark
Published in: bioRxiv, 2021
Publisher: bioRxiv
DOI: 10.1101/2021.10.05.463203

Peer reviewed articles (6)

STARR-seq and UMI-STARR-seq: Assessing Enhancer Activities for Genome-Wide-, High-, and Low-Complexity Candidate Libraries.

Author(s): Christoph Neumayr; Michaela Pagani; Alexander Stark; Alexander Stark; Cosmas D. Arnold
Published in: Current Protocols in Molecular Biology, Issue 2, 2019, ISSN 1934-3647
Publisher: John Wiley and Sons Inc
DOI: 10.1002/cpmb.105

Genome-wide assessment of sequence-intrinsic enhancer responsiveness at single-base-pair resolution

Author(s): Cosmas D Arnold, Muhammad A Zabidi, Michaela Pagani, Martina Rath, Katharina Schernhuber, Tomáš Kazmar, Alexander Stark
Published in: Nature Biotechnology, Issue 35/2, 2017, Page(s) 136-144, ISSN 1087-0156
Publisher: Nature Publishing Group
DOI: 10.1038/nbt.3739

Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation

Author(s): Rui R. Catarino, Alexander Stark
Published in: Genes & Development, Issue 32/3-4, 2018, Page(s) 202-223, ISSN 0890-9369
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.310367.117

Probing the canonicity of the Wnt/Wingless signaling pathway

Author(s): Alexandra Franz, Daria Shlyueva, Erich Brunner, Alexander Stark, Konrad Basler
Published in: PLOS Genetics, Issue 13/4, 2017, Page(s) e1006700, ISSN 1553-7404
Publisher: PLOS Genetics
DOI: 10.1371/journal.pgen.1006700

Resolving systematic errors in widely used enhancer activity assays in human cells

Author(s): Felix Muerdter, Łukasz M Boryń, Ashley R Woodfin, Christoph Neumayr, Martina Rath, Muhammad A Zabidi, Michaela Pagani, Vanja Haberle, Tomáš Kazmar, Rui R Catarino, Katharina Schernhuber, Cosmas D Arnold, Alexander Stark
Published in: Nature Methods, Issue 15/2, 2018, Page(s) 141-149, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/nmeth.4534

A high‐throughput method to identify trans‐activation domains within transcription factor sequences

Author(s): Cosmas D Arnold, Filip Nemčko, Ashley R Woodfin, Sebastian Wienerroither, Anna Vlasova, Alexander Schleiffer, Michaela Pagani, Martina Rath, Alexander Stark
Published in: The EMBO Journal, Issue 37/16, 2018, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.201798896