Metabolomics based biomarkers of dietary intake- new tools for nutrition research

Informazioni relative al progetto

A-DIET

ID dell’accordo di sovvenzione: 647783

DOI 10.3030/647783

Progetto chiuso

Data della firma CE 20 Maggio 2015

Data di avvio 1 Agosto 2015

Data di completamento 31 Luglio 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 995 548,00

Contributo UE € 1 995 548,00

Coordinato da

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland

Pubblicazioni

Peer reviewed articles (33)

Classifying Individuals Into a Dietary Pattern Based on Metabolomic Data

Autori: Orla Prendiville, Janette Walton, Albert Flynn, Anne P. Nugent, Breige A. McNulty, Lorraine Brennan
Pubblicato in: Molecular Nutrition & Food Research, 2021, Pagina/e 2001183, ISSN 1613-4125
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mnfr.202001183

The Role of Protein Intake and its Timing on Body Composition and Muscle Function in Healthy Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Autori: Janine Wirth, Elaine Hillesheim, Lorraine Brennan
Pubblicato in: The Journal of Nutrition, Numero 150/6, 2020, Pagina/e 1443-1460, ISSN 0022-3166
Editore: American Society for Nutritional Sciences
DOI: 10.1093/jn/nxaa049

Optimisation of a metabotype approach to deliver targeted dietary advice

Autori: Elaine Hillesheim, Miriam F. Ryan, Eileen Gibney, Helen M. Roche, Lorraine Brennan
Pubblicato in: Nutrition & Metabolism, Numero 17/1, 2020, ISSN 1743-7075
Editore: BioMed Central
DOI: 10.1186/s12986-020-00499-z

The Potential of Multi-Biomarker Panels in Nutrition Research: Total Fruit Intake as an Example

Autori: Aoife E. McNamara, Janette Walton, Albert Flynn, Anne P. Nugent, Breige A. McNulty, Lorraine Brennan
Pubblicato in: Frontiers in Nutrition, Numero 7, 2021, ISSN 2296-861X
Editore: Frontiers in Nutrition
DOI: 10.3389/fnut.2020.577720

Potential of food intake biomarkers in nutrition research

Autori: Aoife E. McNamara, Lorraine Brennan
Pubblicato in: Proceedings of the Nutrition Society, Numero 79/4, 2020, Pagina/e 487-497, ISSN 0029-6651
Editore: CABI Publishing
DOI: 10.1017/s0029665120007053

Nutrigenomics: lessons learned and future perspectives

Autori: Brennan, L & de Roos, B
Pubblicato in: The American Journal of Clinical Nutrition, Numero 113(3), 2021, Pagina/e 503-516, ISSN 0002-9165
Editore: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqaa366

Metabolomic‐Based Approach to Identify Biomarkers of Apple Intake

Autori: McNamara, A; Collins, C; Sri Harsha,P.S.C; González‐Peña, D; Gibbons, H; McNulty, B Nugent, A.P; Walton, J; Flynn, A; Brennan, L
Pubblicato in: Molecular Nutrition and Food Research, Numero 64(11), 2020, ISSN 1097-0037
Editore: Wiley
DOI: 10.1002/mnfr.201901158

Dysregulation of Lipid Metabolism Precedes Psychosis…So Is Psychosis a Metabolic Disorder?

Autori: David Mongan, Xiaofei Yin, Lorraine Brennan, David R. Cotter
Pubblicato in: Biological Psychiatry, Numero 89/3, 2021, Pagina/e 209-211, ISSN 0006-3223
Editore: Elsevier BV
DOI: 10.1016/j.biopsych.2020.10.017

Metabolomic-based identification of clusters that reflect dietary patterns

Autori: Helena Gibbons, Eibhlin Carr, Breige A. McNulty, Anne P. Nugent, Janette Walton, Albert Flynn, Michael J. Gibney, Lorraine Brennan
Pubblicato in: Molecular Nutrition & Food Research, Numero 61/10, 2017, Pagina/e 1601050, ISSN 1613-4125
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mnfr.201601050

Demonstration of the utility of biomarkers for dietary intake assessment; proline betaine as an example

Autori: Helena Gibbons, Charlotte J. R. Michielsen, Milena Rundle, Gary Frost, Breige A. McNulty, Anne P. Nugent, Janette Walton, Albert Flynn, Michael J. Gibney, Lorraine Brennan
Pubblicato in: Molecular Nutrition & Food Research, Numero 61/10, 2017, Pagina/e 1700037, ISSN 1613-4125
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mnfr.201700037

The role of metabolomics in determination of new dietary biomarkers

Autori: A. O'Gorman, L. Brennan
Pubblicato in: Proceedings of the Nutrition Society, Numero 76/03, 2017, Pagina/e 295-302, ISSN 0029-6651
Editore: CABI Publishing
DOI: 10.1017/S0029665116002974

Metabolomics in nutrition research-a powerful window into nutritional metabolism

Autori: L. Brennan
Pubblicato in: Essays In Biochemistry, Numero 60/5, 2016, Pagina/e 451-458, ISSN 0071-1365
Editore: Portland Press, Ltd.
DOI: 10.1042/EBC20160029

Metabolomics as a tool in the identification of dietary biomarkers

Autori: Helena Gibbons, Lorraine Brennan
Pubblicato in: Proceedings of the Nutrition Society, Numero 76/01, 2017, Pagina/e 42-53, ISSN 0029-6651
Editore: CABI Publishing
DOI: 10.1017/S002966511600032X

A systematic review of metabolite biomarkers of schizophrenia

Autori: Jennifer Davison, Aoife O'Gorman, Lorraine Brennan, David R. Cotter
Pubblicato in: Schizophrenia Research, 2017, ISSN 0920-9964
Editore: Elsevier BV
DOI: 10.1016/j.schres.2017.09.021

Identification of a plasma signature of psychotic disorder in children and adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort

Autori: A O'Gorman, T Suvitaival, L Ahonen, M Cannon, S Zammit, G Lewis, H M Roche, I Mattila, T Hyotylainen, M Oresic, L Brennan, D R Cotter
Pubblicato in: Translational Psychiatry, Numero 7/9, 2017, Pagina/e e1240, ISSN 2158-3188
Editore: Nature Publishing Group
DOI: 10.1038/tp.2017.211

Personalised Interventions—A Precision Approach for the Next Generation of Dietary Intervention Studies

Autori: Baukje de Roos, Lorraine Brennan
Pubblicato in: Nutrients, Numero 9/8, 2017, Pagina/e 847, ISSN 2072-6643
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu9080847

Estimation of Chicken Intake by Adults Using Metabolomics-Derived Markers

Autori: Xiaofei Yin, Helena Gibbons, Milena Rundle, Gary Frost, Breige A McNulty, Anne P Nugent, Janette Walton, Albert Flynn, Michael J Gibney, Lorraine Brennan
Pubblicato in: The Journal of Nutrition, Numero 147/10, 2017, Pagina/e 1850-1857, ISSN 0022-3166
Editore: American Society for Nutritional Sciences
DOI: 10.3945/jn.117.252197

Uncovering Factors Related to Pancreatic Beta-Cell Function

Autori: Curran, Aoife M.; Gibney, Eileen R.; Drummond, Elaine; Brennan, Lorraine; Roche, Helen M.; Ryan, Miriam F.; Gibney, Michael J.
Pubblicato in: PLoS ONE, Numero 1, 2016, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0161350

Use of metabotyping for optimal nutrition

Autori: L Brennan
Pubblicato in: Curr Opin Biotechnol, Numero 44, 2017, Pagina/e 35-38, ISSN 0958-1669
Editore: Elsevier BV
DOI: 10.1016/j.copbio.2016.10.008

Combining biomarker and self-reported dietary intake data: A review of the state of the art and an exposition of concepts

Autori: Isobel Claire Gormley, Yuxin Bai, Lorraine Brennan
Pubblicato in: Statistical Methods in Medical Research, 2019, Pagina/e 096228021983769, ISSN 0962-2802
Editore: SAGE Publications
DOI: 10.1177/0962280219837698

A scheme for a flexible classification of dietary and health biomarkers

Autori: Qian Gao, Giulia Praticò, Augustin Scalbert, Guy Vergères, Marjukka Kolehmainen, Claudine Manach, Lorraine Brennan, Lydia A. Afman, David S. Wishart, Cristina Andres-Lacueva, Mar Garcia-Aloy, Hans Verhagen, Edith J. M. Feskens, Lars O. Dragsted
Pubblicato in: Genes & Nutrition, Numero 12/1, 2017, ISSN 1555-8932
Editore: New Century Health Publishers
DOI: 10.1186/s12263-017-0587-x

Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children

Autori: Francisco Madrid-Gambin, Melanie Föcking, Sophie Sabherwal, Meike Heurich, Jane A. English, Aoife O’Gorman, Tommi Suvitaival, Linda Ahonen, Mary Cannon, Glyn Lewis, Ismo Mattila, Caitriona Scaife, Sean Madden, Tuulia Hyötyläinen, Matej Orešič, Stanley Zammit, Gerard Cagney, David R. Cotter, Lorraine Brennan
Pubblicato in: Biological Psychiatry, Numero 86/1, 2019, Pagina/e 25-34, ISSN 0006-3223
Editore: Elsevier BV
DOI: 10.1016/j.biopsych.2019.01.018

Combining biomarker and food intake data: calibration equations for citrus intake

Autori: Silvia D'Angelo, Isobel Claire Gormley, Breige A McNulty, Anne P Nugent, Janette Walton, Albert Flynn, Lorraine Brennan
Pubblicato in: The American Journal of Clinical Nutrition, Numero 110/4, 2019, Pagina/e 977-983, ISSN 0002-9165
Editore: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqz168

Role of metabolomics in identification of biomarkers related to food intake

Autori: Cassandra Collins, Aoife E. McNamara, Lorraine Brennan
Pubblicato in: Proceedings of the Nutrition Society, Numero 78/02, 2019, Pagina/e 189-196, ISSN 0029-6651
Editore: CABI Publishing
DOI: 10.1017/s002966511900048x

Metabotyping and its role in nutrition research

Autori: Elaine Hillesheim, Lorraine Brennan
Pubblicato in: Nutrition Research Reviews, 2019, Pagina/e 1-10, ISSN 0954-4224
Editore: CABI Publishing
DOI: 10.1017/s0954422419000179

Sex matters: a focus on the impact of biological sex on metabolomic profiles and dietary interventions

Autori: Lorraine Brennan, Helena Gibbons
Pubblicato in: Proceedings of the Nutrition Society, 2019, Pagina/e 1-5, ISSN 0029-6651
Editore: CABI Publishing
DOI: 10.1017/s002966511900106x

The Relationship between Fish Intake and Urinary Trimethylamine‐ N ‐Oxide

Autori: Xiaofei Yin, Helena Gibbons, Milena Rundle, Gary Frost, Breige A. McNulty, Anne P. Nugent, Janette Walton, Albert Flynn, Lorraine Brennan
Pubblicato in: Molecular Nutrition & Food Research, Numero 64/3, 2020, Pagina/e 1900799, ISSN 1613-4125
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mnfr.201900799

Impact of Sample Storage on the NMR Fecal Water Metabolome

Autori: Victoria O’Sullivan, Francisco Madrid-Gambin, Taciane Alegra, Helena Gibbons, Lorraine Brennan
Pubblicato in: ACS Omega, Numero 3/12, 2018, Pagina/e 16585-16590, ISSN 2470-1343
Editore: ACS publications
DOI: 10.1021/acsomega.8b01761

A Metabolomics Approach to the Identification of Urinary Biomarkers of Pea Intake

Autori: Pedapati S.C. Sri Harsha, Roshaida Abdul Wahab, Catalina Cuparencu, Lars Dragsted, Lorraine Brennan
Pubblicato in: Nutrients, Numero 10/12, 2018, Pagina/e 1911, ISSN 2072-6643
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu10121911

Metabolomics-Based Dietary Biomarkers in Nutritional Epidemiology-Current Status and Future Opportunities

Autori: Lorraine Brennan, Frank B. Hu
Pubblicato in: Molecular Nutrition & Food Research, Numero 63/1, 2019, Pagina/e 1701064, ISSN 1613-4125
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mnfr.201701064

Recent Advances in the Application of Metabolomics for Nutrition and Health

Autori: Diana González-Peña, Lorraine Brennan
Pubblicato in: Annual Review of Food Science and Technology, Numero 10/1, 2019, Pagina/e 479-519, ISSN 1941-1413
Editore: Annual Reviews Inc.
DOI: 10.1146/annurev-food-032818-121715

Validation of biomarkers of food intake—critical assessment of candidate biomarkers

Autori: L. O. Dragsted, Q. Gao, A. Scalbert, G. Vergères, M. Kolehmainen, C. Manach, L. Brennan, L. A. Afman, D. S. Wishart, C. Andres Lacueva, M. Garcia-Aloy, H. Verhagen, E. J. M. Feskens, G. Praticò
Pubblicato in: Genes & Nutrition, Numero 13/1, 2018, ISSN 1555-8932
Editore: New Century Health Publishers
DOI: 10.1186/s12263-018-0603-9

Inferring food intake from multiple biomarkers using a latent variable model

Autori: Silvia D'Angelo, Lorraine Brennan, Isobel Claire Gormley
Pubblicato in: The Annals of Applied Statistics, 2021, ISSN 1932-6157
Editore: Institute of Mathematical Statistics