Optoelectrical Dynamics of Ion channel Activation in Calcium Nanodomains

Kv1.3 channel inhibition partially reverts uremia-induced calcification in human aortic vascular smooth muscle cells

Autori: Violeta Cazaña-Pérez, Pilar Cidad-Velasco, Juan F. Navarro-González, Frederic Jaisser, José R. López-López, Diego Alvarez de la Rosa, Teresa Giraldez*, M. Teresa Pérez-García*.
Pubblicato in: Function, 2021, ISSN 2633-8823
Editore: Oxford Academic
DOI: 10.1093/function/zqaa036

Understanding the conformational motions of RCK gating rings

Autori: Teresa Giraldez, Brad S. Rothberg
Pubblicato in: The Journal of General Physiology, Numero 149/4, 2017, Pagina/e 431-441, ISSN 0022-1295
Editore: Rockefeller University Press
DOI: 10.1085/jgp.201611726

Functional validation of Ca 2+ -binding residues from the crystal structure of the BK ion channel

Autori: Aravind S. Kshatri, Alberto J. Gonzalez-Hernandez, Teresa Giraldez
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Biomembranes, Numero 1860/4, 2018, Pagina/e 943-952, ISSN 0005-2736
Editore: Elsevier BV
DOI: 10.1016/j.bbamem.2017.09.023

Interactions of divalent cations with calcium binding sites of BK channels reveal independent motions within the gating ring

Autori: Pablo Miranda, Teresa Giraldez, Miguel Holmgren
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 113/49, 2016, Pagina/e 14055-14060, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1611415113

The GoSlo family of BK channel activators: A no-go for γ subunits?

Autori: Teresa Giraldez
Pubblicato in: Channels, 2016, Pagina/e 1-2, ISSN 1933-6950
Editore: Landes Bioscience
DOI: 10.1080/19336950.2016.1263136

Voltage-dependent dynamics of the BK channel cytosolic gating ring are coupled to the membrane-embedded voltage sensor

Autori: Pablo Miranda, Miguel Holmgren, Teresa Giraldez
Pubblicato in: eLife, Numero 7, 2018, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.40664

Physiological Roles and Therapeutic Potential of Ca2+ Activated Potassium Channels in the Nervous System

Autori: Aravind S. Kshatri, Alberto Gonzalez-Hernandez, Teresa Giraldez
Pubblicato in: Frontiers in Molecular Neuroscience, Numero 11, 2018, ISSN 1662-5099
Editore: Frontiers Research Foundation
DOI: 10.3389/fnmol.2018.00258

SGK1.1 Reduces Kainic Acid-Induced Seizure Severity and Leads to Rapid Termination of Seizures

Autori: Natalia Armas-Capote, Laura E Maglio, Leonel Pérez-Atencio, Elva Martin-Batista, Antonio Reboreda, Juan A Barios, Guadalberto Hernandez, Diego Alvarez de la Rosa, José Antonio Lamas, Luis C Barrio, Teresa Giraldez
Pubblicato in: Cerebral Cortex, 2019, ISSN 1047-3211
Editore: Oxford University Press
DOI: 10.1093/cercor/bhz302

Differential regulation of BK channels by fragile X mental retardation protein

Autori: A. Kshatri1,2, A. Cerrada1,2, R. Gimeno1,2, D. Bartolomé-Martín1,2, P. Rojas3 and T. Giraldez
Pubblicato in: The Journal of General Physiology, 2020, ISSN 1540-7748
Editore: Rockefeller U Press
DOI: 10.1085/jgp.201912502

Activation of SGK1.1 up-regulates the M-current in the presence of epilepsy mutations

Autori: Elva Martin-Batista, Rían W. Manville, Belinda Rivero-Pérez, David Bartolomé-Martín, Diego Alvarez de la Rosa, Geoffrey W. Abbott, Teresa Giraldez
Pubblicato in: Frontiers in Molecular Neuroscience, 2021, ISSN 1662-5099
Editore: Frontiers Research Foundation
DOI: 10.3389/fnmol.2021.798261

Generating new tools for the study of structure-function of ion channels using unnatural amino acids.

Autori: Ariadna Rubio-Cancio, Alberto J. Gonzalez-Hernandez, Teresa Giraldez, Diego Alvarez de la Rosa
Pubblicato in: 2015
Editore: RECI-Annual Meeting Abstract

Molecular basis of BK activation by Ca2+ studied using photoactivatable unnatural aminoacid BzF

Autori: Alberto J. Gonzalez-Hernandez, Diego Alvarez de la Rosa, Teresa Giraldez
Pubblicato in: 2016
Editore: The Biophysical Society

Calcium-gated potassium channels

Autori: Alberto Gonzalez-Hernandez Aravind Kshatri Teresa Giraldez
Pubblicato in: Calcium Signals: From single molecules to physiology, 2022
Editore: IOP-Science

Role of NMDAR-NR2B subunit in the functionality of supramolecular NMDAR-BK complexes

Autori: Rebeca Martinez-Lazaro
Pubblicato in: 2018
Editore: FH Campus Wien University of Applied Sciences

Optoelectrical dynamics of ion channels and calcium nanodomains

Autori: Alberto Gonzalez-Hernandez
Pubblicato in: 2021
Editore: Universidad de La Laguna

Novel neuronal Ca2+ sensors based on the BK channel.

Autori: Roger Gimeno Llobet
Pubblicato in: 2019
Editore: Universidad de La Laguna

Cereblon Regulates BK Channel Expression at Presynaptic and Postsynaptic Sites in Excitatory Synapses

Autori: Ricardo Gomez Laura E Maglio Alberto Gonzalez-Hernandez
Pubblicato in: The Journal of Neuroscience, 2018
Editore: Society for Neuroscience
DOI: 10.1523/jneurosci.1402-18.2018

Neuronal kinase SGK1.1 protects against brain damage after status epilepticus

Autori: Elva Martin-Batista Laura E. Maglio Natalia Armas-Capote Guadalberto Hernandez Diego Alvarez de la Rosa Teresa Giraldez
Pubblicato in: BioRxiv, 2020
Editore: BioRxiv
DOI: 10.1101/2020.04.03.024067

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