Readout of DNA methylation

Project Information

ReaDMe

Grant agreement ID: 667951

DOI 10.3030/667951

Project closed

EC signature date 9 September 2015

Start date 1 January 2016

End date 31 December 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 136 969,00

EU contribution € 2 136 969,00

Coordinated by

FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
Switzerland

Publications

Peer reviewed articles (7)

A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity

Author(s): Paul Adrian Ginno, Dimos Gaidatzis, Angelika Feldmann, Leslie Hoerner, Dilek Imanci, Lukas Burger, Frederic Zilbermann, Antoine H. F. M. Peters, Frank Edenhofer, Sébastien A. Smallwood, Arnaud R. Krebs, Dirk Schübeler
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-16354-x

Mechanisms of OCT4-SOX2 motif readout on nucleosomes

Author(s): Alicia K. Michael, Ralph S. Grand, Luke Isbel, Simone Cavadini, Zuzanna Kozicka, Georg Kempf, Richard D. Bunker, Andreas D. Schenk, Alexandra Graff-Meyer, Ganesh R. Pathare, Joscha Weiss, Syota Matsumoto, Lukas Burger, Dirk Schübeler, Nicolas H. Thomä
Published in: Science, Issue 368/6498, 2020, Page(s) 1460-1465, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abb0074

Molecular Co-occupancy Identifies Transcription Factor Binding Cooperativity In Vivo

Author(s): Can Sönmezer, Rozemarijn Kleinendorst, Dilek Imanci, Guido Barzaghi, Laura Villacorta, Dirk Schübeler, Vladimir Benes, Nacho Molina, Arnaud Regis Krebs
Published in: Molecular Cell, Issue 81/2, 2021, Page(s) 255-267.e6, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.11.015

CG dinucleotides enhance promoter activity independent of DNA methylation

Author(s): Dominik Hartl, Arnaud R. Krebs, Ralph S. Grand, Tuncay Baubec, Luke Isbel, Christiane Wirbelauer, Lukas Burger, Dirk Schübeler
Published in: Genome Research, Issue 29/4, 2019, Page(s) 554-563, ISSN 1088-9051
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.241653.118

Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content

Author(s): Colombo, Daniele F; Burger, Lukas; Baubec, Tuncay; Schübeler, Dirk
Published in: PLoS Genetics, Issue 1, 2017, ISSN 1553-7404
Publisher: Nick Gilbert, Edinburgh Cancer Centre
DOI: 10.5167/uzh-144792

Cis-regulatory landscapes of four cell types of the retina

Author(s): Dominik Hartl, Arnaud R. Krebs, Josephine Jüttner, Botond Roska, Dirk Schübeler
Published in: Nucleic Acids Research, Issue 45/20, 2017, Page(s) 11607-11621, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkx923

Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

Author(s): Paul Adrian Ginno, Lukas Burger, Jan Seebacher, Vytautas Iesmantavicius, Dirk Schübeler
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-06007-5