Skip to main content
Ir a la página de inicio de la Comisión Europea (se abrirá en una nueva ventana)
español español
CORDIS - Resultados de investigaciones de la UE
CORDIS

Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Therapeutic recommendations in Dutch, Greek, German, Italian, Slovene and Spanish (se abrirá en una nueva ventana)

Therapeutic recommendations in Dutch Greek German Italian Slovene and Spanish

Report on ELSI education needs (se abrirá en una nueva ventana)
Report on design of future study employing one promising model (se abrirá en una nueva ventana)
Overall report on ELSI aspects of U-PGx (se abrirá en una nueva ventana)

Overall report on ELSI aspects of UPGx

Survey to evaluate the state of PGx knowledge in the 7 participating countries (se abrirá en una nueva ventana)
Report on ethical issues, guidelines, governance model and principals for patients included in U-PGx (se abrirá en una nueva ventana)

Report on ethical issues guidelines governance model and principals for patients included in UPGx

Establishment of PK models for prediction of DDI and genetic polymorphisms on drug exposure for candidate genes included in the U-PGx trial (se abrirá en una nueva ventana)

Establishment of PK models for prediction of DDI and genetic polymorphisms on drug exposure for candidate genes included in the UPGx trial

Detection, assessment and evaluation of clinically relevant DDI in the U-PGx trial (se abrirá en una nueva ventana)

Detection assessment and evaluation of clinically relevant DDI in the UPGx trial

Report on detailed analysis of existing information infrastructures and requirements of implementation sites (se abrirá en una nueva ventana)
Report on predictions from first model (se abrirá en una nueva ventana)
Analysis of European regulatory requirements (se abrirá en una nueva ventana)
Report on models identified to be developed (se abrirá en una nueva ventana)
Policy recommendations on the pre-emptive use of U-PGx testing in routine clinical practice and uptake by health care systems (se abrirá en una nueva ventana)

Policy recommendations on the preemptive use of UPGx testing in routine clinical practice and uptake by health care systems

Report on comparison of model predictions and observed data from WP4 (se abrirá en una nueva ventana)
Critical re-evaluation and first implementation of revised DPWG guidelines by consideration of relevant DDI (se abrirá en una nueva ventana)

Critical reevaluation and first implementation of revised DPWG guidelines by consideration of relevant DDI

Report on predictions from further models (se abrirá en una nueva ventana)
List of relevant genetic variants for pre-emptive PGx testing (se abrirá en una nueva ventana)

List of relevant genetic variants for preemptive PGx testing

Report on the association of novel genomic variants and extreme phenotypes (se abrirá en una nueva ventana)
Report on finalization endpoint data extraction from clinical database into NONMEM dataset (se abrirá en una nueva ventana)
Report on public events and societal activities in relation with U-PGx (se abrirá en una nueva ventana)

Report on public events and societal activities in relation with UPGx

PGx-guidelines therapeutic recommendations and risk-assessments in English (se abrirá en una nueva ventana)

PGxguidelines therapeutic recommendations and riskassessments in English

Published review paper based upon the current scientific and grey literature on ethics of PGx (se abrirá en una nueva ventana)
Midterm Review (se abrirá en una nueva ventana)
Report on interoperability and development of a shared semantic model (se abrirá en una nueva ventana)
Translated patient surveys for the web-based intensive monitoring system (se abrirá en una nueva ventana)

Translated patient surveys for the webbased intensive monitoring system

Final report on decision support solutions at implementation sites (se abrirá en una nueva ventana)
Organization of a U-PGx Personalized Medicine Day in France (se abrirá en una nueva ventana)

Organization of a UPGx Personalized Medicine Day in France

Organization of the 1st patient/general public oriented PGx information events (se abrirá en una nueva ventana)

Organization of the 1st patientgeneral public oriented PGx information events

Education programme for non-participants (se abrirá en una nueva ventana)

Education programme for nonparticipants

Organization of a U-PGx Personalized Medicine Day in Greece (se abrirá en una nueva ventana)

Organization of a UPGx Personalized Medicine Day in Greece

Organization of a U-PGx Personalized Medicine Day in the UK (se abrirá en una nueva ventana)

Organization of a UPGx Personalized Medicine Day in the UK

Organization of the 3rd patient/general public-oriented PGx information event (se abrirá en una nueva ventana)

Organization of a UPGx Personalized Medicine Day in Germany

Organization of a major 4-day U-PGx Personalized Medicine Symposium in Leiden, Netherlands (se abrirá en una nueva ventana)

Organization of a major 4day UPGx Personalized Medicine Symposium in Leiden Netherlands

Summer school including ELSI topics (prepared by WP8) for medical and pharmacy students (se abrirá en una nueva ventana)

Summer school including ELSI topics prepared by WP8 for medical and pharmacy students

Organization of the 2nd patient/general public oriented PGx information events (se abrirá en una nueva ventana)

Organization of the 2nd patientgeneral public oriented PGx information events

Organization of a U-PGx Personalized Medicine Day in Slovenia (se abrirá en una nueva ventana)

Organization of a UPGx Personalized Medicine Day in Slovenia

Organization of a U-PGx Personalized Medicine Day in Sweden (se abrirá en una nueva ventana)

Organization of a UPGx Personalized Medicine Day in Sweden

Organization of a U-PGx Personalized Medicine Day in Spain (se abrirá en una nueva ventana)

Organization of a UPGx Personalized Medicine Day in Spain

Promotional video will be produced that visualises and promotes the idea of the idea of personalised medicine and pre-emptive PGx testing (se abrirá en una nueva ventana)

Promotional video will be produced that visualises and promotes the idea of the idea of personalised medicine and preemptive PGx testing

Workshop for participating healthcare professionals (se abrirá en una nueva ventana)
Organization of a U-PGx Personalized Medicine Day in Austria (se abrirá en una nueva ventana)

Organization of a UPGx Personalized Medicine Day in Austria

1st version of the public-domain web-based U-PGx information portal (se abrirá en una nueva ventana)

1st version of the publicdomain webbased UPGx information portal

Delivery of decision support solutions including framework for digital infrastructure including secure cloud solutions (se abrirá en una nueva ventana)
Dedicated webpage with secured login access for investigators and study staff (se abrirá en una nueva ventana)
3rd version of the public-domain web-based PGx information portal (se abrirá en una nueva ventana)

3rd version of the publicdomain webbased PGx information portal

Standardized Electronic Case Record Form (eCRF) (se abrirá en una nueva ventana)

Standardized Electronic Case Record Form eCRF

A new model of cost-effectiveness analysis, taking into account the restriction of budget (se abrirá en una nueva ventana)

A new model of costeffectiveness analysis taking into account the restriction of budget

Validated bioinformatics tool (se abrirá en una nueva ventana)
2nd version of the public-domain web-based PGx information portal (se abrirá en una nueva ventana)

2nd version of the publicdomain webbased PGx information portal

A standard cost-effectiveness model to assess cost-effectiveness of PGx testing in each implementation site (se abrirá en una nueva ventana)

A standard costeffectiveness model to assess costeffectiveness of PGx testing in each implementation site

Release of open-source software artefacts for decision support solutions (se abrirá en una nueva ventana)

Release of opensource software artefacts for decision support solutions

eLearning program for the train the trainers concept (se abrirá en una nueva ventana)

Publicaciones

Population pharmacogenomics: an update on ethnogeographic differences and opportunities for precision public health. (se abrirá en una nueva ventana)

Autores: Zhou Y, Lauschke VM.
Publicado en: Human genetics, 2021, ISSN 0340-6717
Editor: Springer Verlag
DOI: 10.1007/s00439-021-02385-x

Tri-Allelic Haplotypes Determine and Differentiate Functionally Normal Allele CYP2D6*2 and Impaired Allele CYP2D6*41. (se abrirá en una nueva ventana)

Autores: Zanger UM, Momoi K, Hofmann U, Schwab M, Klein K.
Publicado en: Clinical pharmacology and therapeutics, 2021, ISSN 0009-9236
Editor: Nature Publishing Group
DOI: 10.1002/cpt.2078

Pharmacogenetics Guidelines: Overview and Comparison of the DPWG, CPIC, CPNDS, and RNPGx Guidelines. (se abrirá en una nueva ventana)

Autores: Abdullah-Koolmees H, van Keulen AM, Nijenhuis M, Deneer VHM.
Publicado en: Frontiers in pharmacology, 2020, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.595219

Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium (se abrirá en una nueva ventana)

Autores: Shefali Setia Verma, Thomas O. Bergmeijer, Li Gong, Jean‐Luc Reny, Joshua P. Lewis, Braxton D. Mitchell, Dimitrios Alexopoulos, Daniel Aradi, Russ B. Altman, Kevin Bliden, Yuki Bradford, Gianluca Campo, Kiyuk Chang, John H. Cleator, Jean‐Pierre Déry, Nadia P. Dridi, Israel Fernandez‐Cadenas, Pierre Fontana, Meinrad Gawaz, Tobias Geisler, Gian Franco Gensini, Betti Giusti, Paul A. Gurbel, Wi
Publicado en: Clinical Pharmacology & Therapeutics, Edición 108/5, 2020, Página(s) 1067-1077, ISSN 0009-9236
Editor: Nature Publishing Group
DOI: 10.1002/cpt.1911

Substrate specificity of CYP2D6 genetic variants. (se abrirá en una nueva ventana)

Autores: van der Lee M, Guchelaar HJ, Swen JJ.
Publicado en: Pharmacogenomics, 2021, ISSN 1462-2416
Editor: Ashley Publications Ltd.
DOI: 10.2217/pgs-2021-0093

Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes (se abrirá en una nueva ventana)

Autores: Delilah F.G. Hendriks, Sabine U. Vorrink, Tomas Smutny, Sarah C. Sim, Åsa Nordling, Shahid Ullah, Masaki Kumondai, Barry C. Jones, Inger Johansson, Tommy B. Andersson, Volker M. Lauschke, Magnus Ingelman‐Sundberg
Publicado en: Clinical Pharmacology & Therapeutics, Edición 108/4, 2020, Página(s) 844-855, ISSN 0009-9236
Editor: Nature Publishing Group
DOI: 10.1002/cpt.1860

Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data (se abrirá en una nueva ventana)

Autores: Maaike van der Lee; William G. Allard; Rolf H. A. M. Vossen; Renee Baak-Pablo; Roberta Menafra; Birgit A. L. M. Deiman; Maarten J. Deenen; Patrick Neven; Inger Johansson; Stefano Gastaldello; Magnus Ingelman-Sundberg; Henk-Jan Guchelaar; Jesse J. Swen; Seyed Yahya Anvar
Publicado en: VOLUME=13;ISSUE=603;TITLE=Science Translational Medicine, Edición 6, 2021, ISSN 1946-6234
Editor: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abf3637

Can CYP Inhibition Overcome Chemotherapy Resistance? (se abrirá en una nueva ventana)

Autores: Magnus Ingelman-Sundberg, Volker M. Lauschke
Publicado en: Trends in Pharmacological Sciences, Edición 41/8, 2020, Página(s) 503-506, ISSN 0165-6147
Editor: Elsevier BV
DOI: 10.1016/j.tips.2020.05.007

Economic evaluation in psychiatric pharmacogenomics: a systematic review. (se abrirá en una nueva ventana)

Autores: Karamperis K, Koromina M, Papantoniou P, Skokou M, Kanellakis F, Mitropoulos K, Vozikis A, Müller DJ, Patrinos GP, Mitropoulou C.
Publicado en: The pharmacogenomics journal, 2021, ISSN 1470-269X
Editor: Nature Publishing Group
DOI: 10.1038/s41397-021-00249-1

IL15RA and SMAD3 Genetic Variants Predict Overall Survival in Metastatic Colorectal Cancer Patients Treated with FOLFIRI Therapy: A New Paradigm. (se abrirá en una nueva ventana)

Autores: De Mattia E, Polesel J, Roncato R, Labriet A, Bignucolo A, Gagno S, Buonadonna A, D'Andrea M, Lévesque E, Jonker D, Couture F, Guillemette C, Cecchin E, Toffoli G.
Publicado en: Cancers, 2021, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13071705

Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs – A study based on blood sample analyses from 24,239 patients (se abrirá en una nueva ventana)

Autores: Robert L Smith, Marit Tveito, Lennart Kyllesø, Marin M Jukic, Magnus Ingelman-Sundberg, Ole A Andreassen, Espen Molden
Publicado en: European Neuropsychopharmacology, Edición 37, 2020, Página(s) 64-69, ISSN 0924-977X
Editor: Elsevier BV
DOI: 10.1016/j.euroneuro.2020.06.007

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone). (se abrirá en una nueva ventana)

Autores: Matic M, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Houwink EJF, Mulder H, Rongen GAPJM, Weide JV, Wilffert B, Swen JJ, Guchelaar HJ, Deneer VHM, van Schaik RHN.
Publicado en: European journal of human genetics : EJHG, 2021, ISSN 1018-4813
Editor: Natue Publishing Group
DOI: 10.1038/s41431-021-00920-y

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine. (se abrirá en una nueva ventana)

Autores: Zhou Y, Arribas GH, Turku A, Jürgenson T, Mkrtchian S, Krebs K, Wang Y, Svobodova B, Milani L, Schulte G, Korabecny J, Gastaldello S, Lauschke VM.
Publicado en: Science advances, 2021, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abi6856

Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost‐Effectiveness of Preemptive Pharmacogenetic Testing (se abrirá en una nueva ventana)

Autores: Yitian Zhou, Kristi Krebs, Lili Milani, Volker M. Lauschke
Publicado en: Clinical Pharmacology & Therapeutics, 2020, ISSN 0009-9236
Editor: Nature Publishing Group
DOI: 10.1002/cpt.1944

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing. (se abrirá en una nueva ventana)

Autores: Lima JJ, Thomas CD, Barbarino J, Desta Z, Van Driest SL, El Rouby N, Johnson JA, Cavallari LH, Shakhnovich V, Thacker DL, Scott SA, Schwab M, Uppugunduri CRS, Formea CM, Franciosi JP, Sangkuhl K, Gaedigk A, Klein TE, Gammal RS, Furuta T.
Publicado en: Clinical pharmacology and therapeutics, 2021, ISSN 0009-9236
Editor: Nature Publishing Group
DOI: 10.1002/cpt.2015

CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations-Implication for Drug Safety, Dosing, and Individualized Therapy. (se abrirá en una nueva ventana)

Autores: Langmia IM, Just KS, Yamoune S, Brockmöller J, Masimirembwa C, Stingl JC.
Publicado en: Frontiers in genetics, 2021, ISSN 1664-8021
Editor: Frontiers Media
DOI: 10.3389/fgene.2021.692234

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2C19 and CYP2D6 and SSRIs. (se abrirá en una nueva ventana)

Autores: Brouwer JMJL, Nijenhuis M, Soree B, Guchelaar HJ, Swen JJ, van Schaik RHN, Weide JV, Rongen GAPJM, Buunk AM, de Boer-Veger NJ, Houwink EJF, van Westrhenen R, Wilffert B, Deneer VHM, Mulder H.
Publicado en: European journal of human genetics : EJHG, 2021, ISSN 1018-4813
Editor: Natue Publishing Group
DOI: 10.1038/s41431-021-01004-7

Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier (se abrirá en una nueva ventana)

Autores: Yitian Zhou, Carolina Dagli Hernandez, Volker M. Lauschke
Publicado en: British Journal of Cancer, 2020, ISSN 0007-0920
Editor: Nature Publishing Group
DOI: 10.1038/s41416-020-01084-0

CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System-Results From the ADRED Study. (se abrirá en una nueva ventana)

Autores: Katja S. Just; Harald Dormann; Mathias Freitag; Marlen Schurig; Miriam Böhme; Michael Steffens; Catharina Scholl; Thomas Seufferlein; Ingo Graeff; Matthias Schwab; Matthias Schwab; Matthias Schwab; Julia C. Stingl
Publicado en: Frontiers in Pharmacology, Edición 9, 2021, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2021.624104

Application of long-read sequencing to elucidate complex pharmacogenomic regions: a proof of principle. (se abrirá en una nueva ventana)

Autores: van der Lee M, Rowell WJ, Menafra R, Guchelaar HJ, Swen JJ, Anvar SY.
Publicado en: The pharmacogenomics journal, 2022, ISSN 1470-269X
Editor: Nature Publishing Group
DOI: 10.1038/s41397-021-00259-z

Generating evidence for precision medicine: considerations made by the Ubiquitous Pharmacogenomics Consortium when designing and operationalizing the PREPARE study (se abrirá en una nueva ventana)

Autores: Cathelijne H. van der Wouden, Stefan Böhringer, Erika Cecchin, Ka-Chun Cheung, Cristina Lucía Dávila-Fajardo, Vera H.M. Deneer, Vita Dolžan, Magnus Ingelman-Sundberg, Siv Jönsson, Mats O. Karlsson, Marjolein Kriek, Christina Mitropoulou, George P. Patrinos, Munir Pirmohamed, Emmanuelle Rial-Sebbag, Matthias Samwald, Matthias Schwab, Daniela Steinberger, Julia Stingl, Gere Sunder-Plassmann, Gi
Publicado en: Pharmacogenetics and Genomics, Edición 30/6, 2020, Página(s) 131-144, ISSN 1744-6872
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/fpc.0000000000000405

Evaluation of the CYP2D6 Haplotype Activity Scores Based on Metabolic Ratios of 4,700 Patients Treated With Three Different CYP2D6 Substrates. (se abrirá en una nueva ventana)

Autores: Jukić MM, Smith RL, Molden E, Ingelman-Sundberg M.
Publicado en: Clinical pharmacology and therapeutics, 2021, ISSN 0009-9236
Editor: Nature Publishing Group
DOI: 10.1002/cpt.2246

Pharmacogenomics in the UK National Health Service: opportunities and challenges. (se abrirá en una nueva ventana)

Autores: Turner RM, Newman WG, Bramon E, McNamee CJ, Wong WL, Misbah S, Hill S, Caulfield M, Pirmohamed M.
Publicado en: Pharmacogenomics, 2020, ISSN 1462-2416
Editor: Ashley Publications Ltd.
DOI: 10.2217/pgs-2020-0091

Pharmacogenomics for Primary Care: An Overview. (se abrirá en una nueva ventana)

Autores: Rollinson V, Turner R, Pirmohamed M.
Publicado en: Genes, 2020, ISSN 2073-4425
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes11111337

The ethnogeographic variability of genetic factors underlying G6PD deficiency (se abrirá en una nueva ventana)

Autores: iamoglou S, Koromina M, Hishinuma E, Yamazaki S, Tsermpini EE, Kordou Z, Fukunaga K, Chantratita W, Zhou Y, Lauschke VM, Mushiroda T, Hiratsuka M, Patrinos GP.
Publicado en: Pharmacological research, 2021, ISSN 1043-6618
Editor: Academic Press
DOI: 10.1016/j.phrs.2021.105904

Diagnostic Test Criteria for HLA Genotyping to Prevent Drug Hypersensitivity Reactions: A Systematic Review of Actionable HLA Recommendations in CPIC and DPWG Guidelines (se abrirá en una nueva ventana)

Autores: Lisanne E. N. Manson, Jesse J. Swen, Henk-Jan Guchelaar
Publicado en: Frontiers in Pharmacology, Edición 11, 2020, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.567048

Characterization of Genetic Heterogeneity in Recurrent Metastases of Renal Cell Carcinoma. (se abrirá en una nueva ventana)

Autores: Sauter-Meyerhoff C, Bohnert R, Mazzola P, Stühler V, Kandabarau S, Büttner FA, Winter S, Herrmann L, Rausch S, Hennenlotter J, Fend F, Scharpf M, Stenzl A, Ossowski S, Bedke J, Schwab M, Schaeffeler E.
Publicado en: Cancers, 2021, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13246221

A Novel CYP2C-Haplotype Associated With Ultrarapid Metabolism of Escitalopram. (se abrirá en una nueva ventana)

Autores: Line Skute Bråten; Tore Haslemo; Marin M. Jukic; Marin M. Jukic; Maxim Ivanov; Magnus Ingelman-Sundberg; Espen Molden; Marianne Kristiansen Kringen
Publicado en: Clinical Pharmacology & Therapeutics, Edición 13, 2021, ISSN 0009-9236
Editor: Nature Publishing Group
DOI: 10.1002/cpt.2233

A Review of the Important Role of CYP2D6 in Pharmacogenomics. (se abrirá en una nueva ventana)

Autores: Taylor C, Crosby I, Yip V, Maguire P, Pirmohamed M, Turner RM.
Publicado en: Genes, 2020, ISSN 2073-4425
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes11111295

Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment. (se abrirá en una nueva ventana)

Autores: Fendt R, Hofmann U, Schneider ARP, Schaeffeler E, Burghaus R, Yilmaz A, Blank LM, Kerb R, Lippert J, Schlender JF, Schwab M, Kuepfer L.
Publicado en: CPT: pharmacometrics & systems pharmacology, 2021, ISSN 2163-8306
Editor: Nature Publishing Group
DOI: 10.1002/psp4.12646

Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status With Antidepressant and Antipsychotic Exposure: A Systematic Review and Meta-analysis. (se abrirá en una nueva ventana)

Autores: Milosavljevic F, Bukvic N, Pavlovic Z, Miljevic C, Pešic V, Molden E, Ingelman-Sundberg M, Leucht S, Jukic MM.
Publicado en: JAMA psychiatry, 2021, ISSN 2168-622X
Editor: American Medical Association
DOI: 10.1001/jamapsychiatry.2020.3643

Individualized versus Standardized Risk Assessment in Patients at High Risk for Adverse Drug Reactions (The IDrug Randomized Controlled Trial)-Never Change a Running System? (se abrirá en una nueva ventana)

Autores: Just KS, Scholl C, Boehme M, Kastenmüller K, Just JM, Bleckwenn M, Holdenrieder S, Meier F, Weckbecker K, Stingl JC.
Publicado en: Pharmaceuticals (Basel, Switzerland), 2021, ISSN 1424-8247
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph14101056

OpenBioLink: a benchmarking framework for large-scale biomedical link prediction (se abrirá en una nueva ventana)

Autores: Anna Breit, Simon Ott, Asan Agibetov, Matthias Samwald
Publicado en: Bioinformatics, Edición 36/13, 2020, Página(s) 4097-4098, ISSN 1367-4803
Editor: Oxford University Press
DOI: 10.1093/bioinformatics/btaa274

Pharmacometrics-Based Considerations for the Design of a Pharmacogenomic Clinical Trial Assessing Irinotecan Safety. (se abrirá en una nueva ventana)

Autores: Minichmayr IK, Karlsson MO, Jönsson S.
Publicado en: Pharmaceutical research, 2021, ISSN 0724-8741
Editor: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11095-021-03024-w

Rates of complete nonadherence among atypical antipsychotic drugs: A study using blood samples from 13,217 outpatients with psychotic disorders. (se abrirá en una nueva ventana)

Autores: Smith RL, Tveito M, Kyllesø L, Jukic MM, Ingelman-Sundberg M, Andreassen OA, Molden E.
Publicado en: Schizophrenia research, 2021, ISSN 0920-9964
Editor: Elsevier BV
DOI: 10.1016/j.schres.2020.11.025

Genotyping for HLA Risk Alleles to Prevent Drug Hypersensitivity Reactions: Impact Analysis. (se abrirá en una nueva ventana)

Autores: Manson LEN, van den Hout WB, Guchelaar HJ.
Publicado en: Pharmaceuticals (Basel, Switzerland), 2021, ISSN 1424-8247
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph15010004

Pharmacogenomics of anticancer drugs: Personalising the choice and dose to manage drug response. (se abrirá en una nueva ventana)

Autores: Carr DF, Turner RM, Pirmohamed M.
Publicado en: British journal of clinical pharmacology, 2021, ISSN 0306-5251
Editor: Blackwell Publishing Inc.
DOI: 10.1111/bcp.14407

Technologies for Pharmacogenomics: A Review. (se abrirá en una nueva ventana)

Autores: van der Lee M, Kriek M, Guchelaar HJ, Swen JJ.
Publicado en: Genes, 2020, ISSN 2073-4425
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes11121456

Physiologically Based Precision Dosing Approach for Drug-Drug-Gene Interactions: A Simvastatin Network Analysis. (se abrirá en una nueva ventana)

Autores: Wojtyniak JG, Selzer D, Schwab M, Lehr T.
Publicado en: Clinical pharmacology and therapeutics, 2021, ISSN 0009-9236
Editor: Nature Publishing Group
DOI: 10.1002/cpt.2111

Buscando datos de OpenAIRE...

Se ha producido un error en la búsqueda de datos de OpenAIRE

No hay resultados disponibles

Mi folleto 0 0