Leistungen
Therapeutic recommendations in Dutch Greek German Italian Slovene and Spanish
Report on ELSI education needsReport on design of future study employing one promising model
Overall report on ELSI aspects of U-PGx
Overall report on ELSI aspects of UPGx
Survey to evaluate the state of PGx knowledge in the 7 participating countriesReport on ethical issues, guidelines, governance model and principals for patients included in U-PGx
Report on ethical issues guidelines governance model and principals for patients included in UPGx
Establishment of PK models for prediction of DDI and genetic polymorphisms on drug exposure for candidate genes included in the U-PGx trialEstablishment of PK models for prediction of DDI and genetic polymorphisms on drug exposure for candidate genes included in the UPGx trial
Detection, assessment and evaluation of clinically relevant DDI in the U-PGx trialDetection assessment and evaluation of clinically relevant DDI in the UPGx trial
Report on detailed analysis of existing information infrastructures and requirements of implementation sitesReport on predictions from first model
Analysis of European regulatory requirements
Report on models identified to be developed
Policy recommendations on the pre-emptive use of U-PGx testing in routine clinical practice and uptake by health care systems
Policy recommendations on the preemptive use of UPGx testing in routine clinical practice and uptake by health care systems
Report on comparison of model predictions and observed data from WP4Critical re-evaluation and first implementation of revised DPWG guidelines by consideration of relevant DDI
Critical reevaluation and first implementation of revised DPWG guidelines by consideration of relevant DDI
Report on predictions from further modelsList of relevant genetic variants for pre-emptive PGx testing
List of relevant genetic variants for preemptive PGx testing
Report on the association of novel genomic variants and extreme phenotypesReport on finalization endpoint data extraction from clinical database into NONMEM dataset
Report on public events and societal activities in relation with U-PGx
Report on public events and societal activities in relation with UPGx
PGx-guidelines therapeutic recommendations and risk-assessments in EnglishPGxguidelines therapeutic recommendations and riskassessments in English
Published review paper based upon the current scientific and grey literature on ethics of PGxMidterm Review
Report on interoperability and development of a shared semantic model
Translated patient surveys for the web-based intensive monitoring system
Translated patient surveys for the webbased intensive monitoring system
Final report on decision support solutions at implementation sitesOrganization of a UPGx Personalized Medicine Day in France
Organization of the 1st patient/general public oriented PGx information eventsOrganization of the 1st patientgeneral public oriented PGx information events
Education programme for non-participantsEducation programme for nonparticipants
Organization of a U-PGx Personalized Medicine Day in GreeceOrganization of a UPGx Personalized Medicine Day in Greece
Organization of a U-PGx Personalized Medicine Day in the UKOrganization of a UPGx Personalized Medicine Day in the UK
Organization of the 3rd patient/general public-oriented PGx information eventOrganization of a UPGx Personalized Medicine Day in Germany
Organization of a major 4-day U-PGx Personalized Medicine Symposium in Leiden, NetherlandsOrganization of a major 4day UPGx Personalized Medicine Symposium in Leiden Netherlands
Summer school including ELSI topics (prepared by WP8) for medical and pharmacy studentsSummer school including ELSI topics prepared by WP8 for medical and pharmacy students
Organization of the 2nd patient/general public oriented PGx information eventsOrganization of the 2nd patientgeneral public oriented PGx information events
Organization of a U-PGx Personalized Medicine Day in SloveniaOrganization of a UPGx Personalized Medicine Day in Slovenia
Organization of a U-PGx Personalized Medicine Day in SwedenOrganization of a UPGx Personalized Medicine Day in Sweden
Organization of a U-PGx Personalized Medicine Day in SpainOrganization of a UPGx Personalized Medicine Day in Spain
Promotional video will be produced that visualises and promotes the idea of the idea of personalised medicine and pre-emptive PGx testingPromotional video will be produced that visualises and promotes the idea of the idea of personalised medicine and preemptive PGx testing
Workshop for participating healthcare professionalsOrganization of a U-PGx Personalized Medicine Day in Austria
Organization of a UPGx Personalized Medicine Day in Austria
1st version of the publicdomain webbased UPGx information portal
Delivery of decision support solutions including framework for digital infrastructure including secure cloud solutionsDedicated webpage with secured login access for investigators and study staff
3rd version of the public-domain web-based PGx information portal
3rd version of the publicdomain webbased PGx information portal
Standardized Electronic Case Record Form (eCRF)Standardized Electronic Case Record Form eCRF
A new model of cost-effectiveness analysis, taking into account the restriction of budgetA new model of costeffectiveness analysis taking into account the restriction of budget
Validated bioinformatics tool2nd version of the public-domain web-based PGx information portal
2nd version of the publicdomain webbased PGx information portal
A standard cost-effectiveness model to assess cost-effectiveness of PGx testing in each implementation siteA standard costeffectiveness model to assess costeffectiveness of PGx testing in each implementation site
Release of open-source software artefacts for decision support solutionsRelease of opensource software artefacts for decision support solutions
eLearning program for the train the trainers conceptRelease of opensource software artefacts describing semantic model
ELSI content for a summer school on PGx to be delivered by WP6set of specifications for the selected PGx assays
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Pharmacogenomics, 2021, ISSN 1462-2416
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