Role of Apolipoproteins L in immunity and disease

Informazioni relative al progetto

APOLs

ID dell’accordo di sovvenzione: 669007

DOI 10.3030/669007

Progetto chiuso

Data della firma CE 7 Agosto 2015

Data di avvio 1 Settembre 2015

Data di completamento 30 Giugno 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 2 250 000,00

Contributo UE € 2 250 000,00

Coordinato da

UNIVERSITE LIBRE DE BRUXELLES
Belgium

Pubblicazioni

Peer reviewed articles (12)

The function of apolipoproteins L (APOLs): relevance for kidney disease, neurotransmission disorders, cancer and viral infection

Autori: Etienne Pays
Pubblicato in: The FEBS Journal, Numero 288/2, 2021, Pagina/e 360-381, ISSN 1742-464X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/febs.15444

The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity

Autori: Laurence Lecordier, Sophie Uzureau, Gilles Vanwalleghem, Magali Deleu, Jean-Marc Crowet, Paul Barry, Barry Moran, Paul Voorheis, Andra-Cristina Dumitru, Yoshiki Yamaryo-Botté, Marc Dieu, Patricia Tebabi, Benoit Vanhollebeke, Laurence Lins, Cyrille Y. Botté, David Alsteens, Yves Dufrêne, David Pérez-Morga, Derek P. Nolan, Etienne Pays
Pubblicato in: iScience, Numero 23/9, 2020, Pagina/e 101476, ISSN 2589-0042
Editore: NA
DOI: 10.1016/j.isci.2020.101476

The Mechanism of Kidney Disease Due to APOL1 Risk Variants

Autori: Etienne Pays
Pubblicato in: Journal of the American Society of Nephrology, Numero 31/11, 2020, Pagina/e 2502-2505, ISSN 1046-6673
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2020070954

APOLs with low pH dependence can kill all African trypanosomes

Autori: Frédéric Fontaine, Laurence Lecordier, Gilles Vanwalleghem, Pierrick Uzureau, Nick Van Reet, Martina Fontaine, Patricia Tebabi, Benoit Vanhollebeke, Philippe Büscher, David Pérez-Morga, Etienne Pays
Pubblicato in: Nature Microbiology, Numero 2/11, 2017, Pagina/e 1500-1506, ISSN 2058-5276
Editore: Nature Publishing Group
DOI: 10.1038/s41564-017-0034-1

Trypanosoma brucei growth control by TNF in mammalian host is independent of the soluble form of the cytokine

Autori: Gilles Vanwalleghem, Yannick Morias, Alain Beschin, David E. Szymkowski, Etienne Pays
Pubblicato in: Scientific Reports, Numero 7/1, 2017, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-017-06496-2

Specific Endocytosis Blockade of Trypanosoma cruzi Exposed to a Poly-LAcNAc Binding Lectin Suggests that Lectin-Sugar Interactions Participate to Receptor-Mediated Endocytosis

Autori: Sébastien Brosson, Frédéric Fontaine, Marjorie Vermeersch, David Perez-Morga, Etienne Pays, Sabrina Bousbata, Didier Salmon
Pubblicato in: PLOS ONE, Numero 11/9, 2016, Pagina/e e0163302, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0163302

Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells.

Autori: Uzureau, S., Coquerelle, C., Uzureau, P., Vermeiren, C., Pilotte, L., Van Acker, A., Acolty, V., Vanhollebeke, B., Van den Eynde, B., Moser, M., and Pays, E.
Pubblicato in: European Journal of Immunology, 2016, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201546252

APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin

Autori: Sophie Uzureau, Laurence Lecordier, Pierrick Uzureau, Dorle Hennig, Jonas H. Graversen, Fabrice Homblé, Pepe Ekulu Mfutu, Fanny Oliveira Arcolino, Ana Raquel Ramos, Rita M. La Rovere, Tomas Luyten, Marjorie Vermeersch, Patricia Tebabi, Marc Dieu, Bart Cuypers, Stijn Deborggraeve, Marion Rabant, Christophe Legendre, Søren K. Moestrup, Elena Levtchenko, Geert Bultynck, Christophe Erneux, David Pé
Pubblicato in: Cell Reports, Numero 30/11, 2020, Pagina/e 3821-3836.e13, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.02.064

Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection

Autori: Bart Cuypers, Laurence Lecordier, Conor J. Meehan, Frederik Van den Broeck, Hideo Imamura, Philippe Büscher, Jean-Claude Dujardin, Kris Laukens, Achim Schnaufer, Caroline Dewar, Michael Lewis, Oliver Balmer, Thomas Azurago, Sardick Kyei-Faried, Sally-Ann Ohene, Boateng Duah, Prince Homiah, Ebenezer Kofi Mensah, Francis Anleah, Jose Ramon Franco, Etienne Pays, Stijn Deborggraeve
Pubblicato in: mBio, Numero 7/2, 2016, ISSN 2150-7511
Editore: The American Society for Microbiology
DOI: 10.1128/mBio.02198-15

Genetic and immunological basis of human African trypanosomiasis

Autori: Etienne Pays, Derek P Nolan
Pubblicato in: Current Opinion in Immunology, Numero 72, 2021, Pagina/e 13-20, ISSN 0952-7915
Editore: Elsevier BV
DOI: 10.1016/j.coi.2021.02.007

APOL1 variant–associated kidney disease: from trypanosomes to podocyte cytoskeleton

Autori: Etienne Pays
Pubblicato in: Kidney International, Numero 98/6, 2020, Pagina/e 1373-1377, ISSN 0085-2538
Editore: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2020.07.034

Multiparametric Atomic Force Microscopy Identifies Multiple Structural and Physical Heterogeneities on the Surface of Trypanosoma brucei

Autori: Claire Valotteau, Andra C. Dumitru, Laurence Lecordier, David Alsteens, Etienne Pays, David Pérez-Morga, Yves F. Dufrêne
Pubblicato in: ACS Omega, Numero 5/33, 2020, Pagina/e 20953-20959, ISSN 2470-1343
Editore: NA
DOI: 10.1021/acsomega.0c02416