Presynaptic Regulatory Principles in Synaptic Plasticity, Neuronal Network Function, and Behaviour

Informazioni relative al progetto

SYNPRIME

ID dell’accordo di sovvenzione: 670283

DOI 10.3030/670283

Progetto chiuso

Data della firma CE 14 Agosto 2015

Data di avvio 1 Settembre 2015

Data di completamento 31 Agosto 2020

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 2 495 593,75

Contributo UE € 2 495 593,75

Coordinato da

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

Pubblicazioni

Peer reviewed articles (11)

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors

Autori: Lin Luo, Mateusz C. Ambrozkiewicz, Fritz Benseler, Cui Chen, Emilie Dumontier, Susanne Falkner, Elisabetta Furlanis, Andrea M. Gomez, Naosuke Hoshina, Wei-Hsiang Huang, Mary Anne Hutchison, Yu Itoh-Maruoka, Laura A. Lavery, Wei Li, Tomohiko Maruo, Junko Motohashi, Emily Ling-Lin Pai, Kenneth A. Pelkey, Ariane Pereira, Thomas Philips, Jennifer L. Sinclair, Jeff A. Stogsdill, Lisa Traunmüller, Jiex
Pubblicato in: Neuron, Numero 106/1, 2020, Pagina/e 37-65.e5, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2020.01.008

Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice

Autori: Yuji Okamoto, Noa Lipstein, Yunfeng Hua, Kun-Han Lin, Nils Brose, Takeshi Sakaba, Mitsuharu Midorikawa
Pubblicato in: eLife, Numero 5, 2016, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/eLife.14643

Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder

Autori: Noa Lipstein, Nanda M. Verhoeven-Duif, Francesco E. Michelassi, Nathaniel Calloway, Peter M. van Hasselt, Katarzyna Pienkowska, Gijs van Haaften, Mieke M. van Haelst, Ron van Empelen, Inge Cuppen, Heleen C. van Teeseling, Annemieke M.V. Evelein, Jacob A. Vorstman, Sven Thoms, Olaf Jahn, Karen J. Duran, Glen R. Monroe, Timothy A. Ryan, Holger Taschenberger, Jeremy S. Dittman, Jeong-Seop Rhee, Gepke
Pubblicato in: Journal of Clinical Investigation, Numero 127/3, 2017, Pagina/e 1005-1018, ISSN 0021-9738
Editore: American Society for Clinical Investigation
DOI: 10.1172/JCI90259

Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release

Autori: Albrecht Sigler, Won Chan Oh, Cordelia Imig, Bekir Altas, Hiroshi Kawabe, Benjamin H. Cooper, Hyung-Bae Kwon, Jeong-Seop Rhee, Nils Brose
Pubblicato in: Neuron, Numero 94/2, 2017, Pagina/e 304-311.e4, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2017.03.029

ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones

Autori: Hiroshi Kawabe, Miso Mitkovski, Pascal S. Kaeser, Johannes Hirrlinger, Felipe Opazo, Dennis Nestvogel, Stefan Kalla, Anna Fejtova, Sophie E. Verrier, Simon R. Bungers, Benjamin H. Cooper, Frederique Varoqueaux, Yun Wang, Ralf B. Nehring, Eckart D. Gundelfinger, Christian Rosenmund, Silvio O. Rizzoli, Thomas C. Südhof, Jeong-Seop Rhee, Nils Brose
Pubblicato in: The Journal of Cell Biology, Numero 216/4, 2017, Pagina/e 1143-1161, ISSN 0021-9525
Editore: Rockefeller University Press
DOI: 10.1083/jcb.201606086

Dynamically Primed Synaptic Vesicle States: Key to Understand Synaptic Short-Term Plasticity

Autori: Erwin Neher, Nils Brose
Pubblicato in: Neuron, Numero 100/6, 2018, Pagina/e 1283-1291, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2018.11.024

Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release

Autori: Francisco José López-Murcia, Kerstin Reim, Olaf Jahn, Holger Taschenberger, Nils Brose
Pubblicato in: Cell Reports, Numero 26/10, 2019, Pagina/e 2521-2530.e5, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2019.02.030

Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses

Autori: Lydia Maus, ChoongKu Lee, Bekir Altas, Sinem M. Sertel, Kirsten Weyand, Silvio O. Rizzoli, JeongSeop Rhee, Nils Brose, Cordelia Imig, Benjamin H. Cooper
Pubblicato in: Cell Reports, Numero 30/11, 2020, Pagina/e 3632-3643.e8, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.02.083

The Synaptic Vesicle Priming Protein CAPS-1 Shapes the Adaptation of Sensory Evoked Responses in Mouse Visual Cortex

Autori: Dennis B. Nestvogel, Ricardo Martins Merino, Carolina Leon-Pinzon, Manuel Schottdorf, ChoongKu Lee, Cordelia Imig, Nils Brose, Jeong-Seop Rhee
Pubblicato in: Cell Reports, Numero 30/10, 2020, Pagina/e 3261-3269.e4, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.02.045

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Autori: Frank Koopmans, Pim van Nierop, Maria Andres-Alonso, Andrea Byrnes, Tony Cijsouw, Marcelo P. Coba, L. Niels Cornelisse, Ryan J. Farrell, Hana L. Goldschmidt, Daniel P. Howrigan, Natasha K. Hussain, Cordelia Imig, Arthur P.H. de Jong, Hwajin Jung, Mahdokht Kohansalnodehi, Barbara Kramarz, Noa Lipstein, Ruth C. Lovering, Harold MacGillavry, Vittoria Mariano, Huaiyu Mi, Momchil Ninov, David Osumi-Sut
Pubblicato in: Neuron, Numero 103/2, 2019, Pagina/e 217-234.e4, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2019.05.002

Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices

Autori: Cordelia Imig, Francisco José López-Murcia, Lydia Maus, Inés Hojas García-Plaza, Lena Sünke Mortensen, Manuela Schwark, Valentin Schwarze, Julie Angibaud, U. Valentin Nägerl, Holger Taschenberger, Nils Brose, Benjamin H. Cooper
Pubblicato in: Neuron, 2020, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2020.09.004