European Network linking informatics and genomics of helper T cells

Risultati finali

Electronic newsletter

NA

Betaversion of website

NA

International Symposium

NA

Midterm review meeting

Compulsory deliverable

Conference attendance

NA

Network of stakeholders

NA

Binding site prediction algorithm

NA

Awarding of PhD/doctoral degrees

NA

Certificates for ESRs on completion of various courses

NA

Pubblicazioni

Cellular Stress in the Context of an Inflammatory Environment Supports TGF-β-Independent T Helper-17 Differentiation

Autori: Verena Brucklacher-Waldert, Cristina Ferreira, Marisa Stebegg, Olivier Fesneau, Silvia Innocentin, Julien C. Marie, Marc Veldhoen
Pubblicato in: Cell Reports, Numero 19/11, 2017, Pagina/e 2357-2370, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2017.05.052

ROTS: An R package for reproducibility-optimized statistical testing

Autori: Tomi Suomi, Fatemeh Seyednasrollah, Maria K. Jaakkola, Thomas Faux, Laura L. Elo
Pubblicato in: PLOS Computational Biology, Numero 13/5, 2017, Pagina/e e1005562, ISSN 1553-7358
Editore: Public Library of Science
DOI: 10.1371/journal.pcbi.1005562

Follicular T Helper Cells: A New Marker of Type 1 Diabetes Risk?

Autori: Frank Heuts, Natalie M. Edner, Lucy S.K. Walker
Pubblicato in: Diabetes, Numero 66/2, 2017, Pagina/e 258-260, ISSN 0012-1797
Editore: American Diabetes Association
DOI: 10.2337/dbi16-0062

Regulation of the Germinal Center Response

Autori: Marisa Stebegg, Saumya D. Kumar, Alyssa Silva-Cayetano, Valter R. Fonseca, Michelle A. Linterman, Luis Graca
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2018.02469

Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation

Autori: Ricardo J. Miragaia, Tomás Gomes, Agnieszka Chomka, Laura Jardine, Angela Riedel, Ahmed N. Hegazy, Natasha Whibley, Andrea Tucci, Xi Chen, Ida Lindeman, Guy Emerton, Thomas Krausgruber, Jacqueline Shields, Muzlifah Haniffa, Fiona Powrie, Sarah A. Teichmann
Pubblicato in: Immunity, Numero 50/2, 2019, Pagina/e 493-504.e7, ISSN 1074-7613
Editore: Cell Press
DOI: 10.1016/j.immuni.2019.01.001

Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation

Autori: Jhuma Pramanik, Xi Chen, Gozde Kar, Johan Henriksson, Tomás Gomes, Jong-Eun Park, Kedar Natarajan, Kerstin B. Meyer, Zhichao Miao, Andrew N. J. McKenzie, Bidesh Mahata, Sarah A. Teichmann
Pubblicato in: Genome Medicine, Numero 10/1, 2018, ISSN 1756-994X
Editore: BioMed Central
DOI: 10.1186/s13073-018-0589-3

Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation

Autori: Johan Henriksson, Xi Chen, Tomás Gomes, Ubaid Ullah, Kerstin B. Meyer, Ricardo Miragaia, Graham Duddy, Jhuma Pramanik, Kosuke Yusa, Riitta Lahesmaa, Sarah A. Teichmann
Pubblicato in: Cell, Numero 176/4, 2019, Pagina/e 882-896.e18, ISSN 0092-8674
Editore: Cell Press
DOI: 10.1016/j.cell.2018.11.044

CTLA-4–mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells

Autori: Vitalijs Ovcinnikovs, Ellen M. Ross, Lina Petersone, Natalie M. Edner, Frank Heuts, Elisavet Ntavli, Alexandros Kogimtzis, Alan Kennedy, Chun Jing Wang, Clare L. Bennett, David M. Sansom, Lucy S. K. Walker
Pubblicato in: Science Immunology, Numero 4/35, 2019, Pagina/e eaaw0902, ISSN 2470-9468
Editore: AAAS
DOI: 10.1126/sciimmunol.aaw0902

T Cell/B Cell Collaboration and Autoimmunity: An Intimate Relationship

Autori: Lina Petersone, Natalie M. Edner, Vitalijs Ovcinnikovs, Frank Heuts, Ellen M. Ross, Elisavet Ntavli, Chun J. Wang, Lucy S. K. Walker
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2018.01941

Heterochronic faecal transplantation boosts gut germinal centres in aged mice

Autori: Marisa Stebegg, Alyssa Silva-Cayetano, Silvia Innocentin, Timothy P. Jenkins, Cinzia Cantacessi, Colin Gilbert, Michelle A. Linterman
Pubblicato in: Nature Communications, Numero 10/1, 2019, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-019-10430-7

RepViz: a replicate-driven R tool for visualizing genomic regions

Autori: Thomas Faux, Kalle T. Rytkönen, Asta Laiho, Laura L. Elo
Pubblicato in: BMC Research Notes, Numero 12/1, 2019, ISSN 1756-0500
Editore: BioMed Central
DOI: 10.1186/s13104-019-4473-z

Molecular Markers Distinguishing T Cell Subtypes With TSDR Strand-Bias Methylation

Autori: Ekaterina Minskaia, Barbara C. Saraiva, Maria M. V. Soares, Rita I. Azevedo, Ruy M. Ribeiro, Saumya D. Kumar, Ana I. S. Vieira, João F. Lacerda
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2018.02540

Immune Cell Dynamics Unfolded by Single-Cell Technologies

Autori: Daniel J. Kunz, Tomás Gomes, Kylie R. James
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2018.01435

Immunology Driven by Large-Scale Single-Cell Sequencing

Autori: Tomás Gomes, Sarah A. Teichmann, Carlos Talavera-López
Pubblicato in: Trends in Immunology, Numero 40/11, 2019, Pagina/e 1011-1021, ISSN 1471-4906
Editore: Elsevier BV
DOI: 10.1016/j.it.2019.09.004

Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation

Autori: Yi-Ling Chen, Tomas Gomes, Clare S. Hardman, Felipe A. Vieira Braga, Danuta Gutowska-Owsiak, Maryam Salimi, Nicki Gray, David A. Duncan, Gary Reynolds, David Johnson, Mariolina Salio, Vincenzo Cerundolo, Jillian L. Barlow, Andrew N.J. McKenzie, Sarah A. Teichmann, Muzlifah Haniffa, Graham Ogg
Pubblicato in: The Journal of Experimental Medicine, Numero 217/3, 2020, ISSN 0022-1007
Editore: Rockefeller University Press
DOI: 10.1084/jem.20190811

Metabolic pathways in T cell activation and lineage differentiation

Autori: Luís Almeida, Matthias Lochner, Luciana Berod, Tim Sparwasser
Pubblicato in: Seminars in Immunology, Numero 28/5, 2016, Pagina/e 514-524, ISSN 1044-5323
Editore: Academic Press
DOI: 10.1016/j.smim.2016.10.009

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