Mediation of stem cell identity and aging by proteostasis

Pubblicazioni

The intrinsic chaperone network of Arabidopsis stem cells confers protection against proteotoxic stress

Autori: Ernesto Llamas, Salvador Torres‐Montilla, Hyun Ju Lee, María Victoria Barja, Elena Schlimgen, Nick Dunken, Prerana Wagle, Wolfgang Werr, Alga Zuccaro, Manuel Rodríguez‐Concepción, David Vilchez
Pubblicato in: Aging Cell, Numero 20/8, 2021, ISSN 1474-9718
Editore: Blackwell Publishing Inc.
DOI: 10.1111/acel.13446

Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans

Autori: Giuseppe Calculli, Hyun Ju Lee, Koning Shen, Uyen Pham, Marija Herholz, Aleksandra Trifunovic, Andrew Dillin, David Vilchez
Pubblicato in: Science Advances, Numero 7/26, 2021, Pagina/e eabg3012, ISSN 2375-2548
Editore: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.abg3012

The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells

Autori: Azra Fatima, Dilber Irmak, Alireza Noormohammadi, Markus M. Rinschen, Aniruddha Das, Orsolya Leidecker, Christina Schindler, Víctor Sánchez-Gaya, Prerana Wagle, Wojciech Pokrzywa, Thorsten Hoppe, Alvaro Rada-Iglesias, David Vilchez
Pubblicato in: Communications Biology, Numero 3/1, 2020, ISSN 2399-3642
Editore: Springer Nature
DOI: 10.1038/s42003-020-0984-3

Rewiring of the ubiquitinated proteome determines ageing in C. elegans

Autori: Seda Koyuncu, Rute Loureiro, Hyun Ju Lee, Prerana Wagle, Marcus Krueger, David Vilchez
Pubblicato in: Nature, Numero 596/7871, 2021, Pagina/e 285-290, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-021-03781-z

A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells

Autori: Hyun Ju Lee, Deniz Bartsch, Cally Xiao, Santiago Guerrero, Gaurav Ahuja, Christina Schindler, James J. Moresco, John R. Yates, Fátima Gebauer, Hisham Bazzi, Christoph Dieterich, Leo Kurian, David Vilchez
Pubblicato in: Nature Communications, Numero 8/1, 2017, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-017-01744-5

Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan

Autori: Alireza Noormohammadi, Amirabbas Khodakarami, Ricardo Gutierrez-Garcia, Hyun Ju Lee, Seda Koyuncu, Tim König, Christina Schindler, Isabel Saez, Azra Fatima, Christoph Dieterich, David Vilchez
Pubblicato in: Nature Communications, Numero 7, 2016, Pagina/e 13649, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/ncomms13649

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients

Autori: Seda Koyuncu, Isabel Saez, Hyun Ju Lee, Ricardo Gutierrez-Garcia, Wojciech Pokrzywa, Azra Fatima, Thorsten Hoppe, David Vilchez
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-05320-3

Insights into the ubiquitin-proteasome system of human embryonic stem cells

Autori: Isabel Saez, Seda Koyuncu, Ricardo Gutierrez-Garcia, Christoph Dieterich, David Vilchez
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-22384-9

Prostaglandin signals from adult germline stem cells delay somatic ageing of Caenorhabditis elegans

Autori: Hyun Ju Lee, Alireza Noormohammadi, Seda Koyuncu, Giuseppe Calculli, Milos S. Simic, Marija Herholz, Aleksandra Trifunovic, David Vilchez
Pubblicato in: Nature Metabolism, Numero 1/8, 2019, Pagina/e 790-810, ISSN 2522-5812
Editore: Springer Nature
DOI: 10.1038/s42255-019-0097-9

È in corso la ricerca di dati su OpenAIRE...

Pubblicazioni

Condividi questa pagina

Scarica