Pubblicazioni Peer reviewed articles (16) Constrained Peptides with Fine‐Tuned Flexibility Inhibit NF‐Y Transcription Factor Assembly Autori: Sadasivam Jeganathan, Mathias Wendt, Sebastian Kiehstaller, Diego Brancaccio, Arne Kuepper, Nicole Pospiech, Alfonso Carotenuto, Ettore Novellino, Sven Hennig, Tom N. Grossmann Pubblicato in: Angewandte Chemie, Issue 131/48, 2019, Page(s) 17512-17519, ISSN 0044-8249 Editore: John Wiley & Sons Ltd. DOI: 10.1002/ange.201907901 Protein Macrocyclization for Tertiary Structure Stabilization Autori: Haim, Anissa; Neubacher, Saskia; Grossmann, Tom N. Pubblicato in: Chembiochem, Issue 2, 2021, ISSN 1439-4227 Editore: John Wiley & Sons Ltd. DOI: 10.1002/cbic.202100111 In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability Autori: Saskia Neubacher, Jordy M. Saya, Alessia Amore, Tom N. Grossmann Pubblicato in: The Journal of Organic Chemistry, Issue 85/3, 2019, Page(s) 1476-1483, ISSN 0022-3263 Editore: American Chemical Society DOI: 10.1021/acs.joc.9b02490 Synergistic DNA- and Protein-Based Recognition Promote an RNA-Templated Bio-orthogonal Reaction Autori: McLoughlin, Niall M.; Kuepper, Arne; Neubacher, Saskia; Grossmann, Tom N. Pubblicato in: Chemistry a European Journal, Issue 1, 2021, ISSN 0947-6539 Editore: John Wiley & Sons Ltd. DOI: 10.1002/chem.202101103 Constrained peptides mimic a viral suppressor of RNA silencing Autori: Arne Kuepper; Niall M McLoughlin; Saskia Neubacher; Alejandro Yeste-Vázquez; Estel Collado Camps; Chandran Nithin; Sunandan Mukherjee; Lucas Bethge; Janusz M Bujnicki; Roland Brock; Stefan Heinrichs; Tom N Grossmann Pubblicato in: Nucleic acids research, Issue 1, 2021, ISSN 0305-1048 Editore: Oxford University Press DOI: 10.1093/nar/gkab1149 Acetylene containing cyclo(L-Tyr-L-Tyr)-analogs as mechanism-based inhibitors of CYP121A1 from Mycobacterium tuberculosis. Autori: Sandra Ortega Ugalde; Kerstin Wallraven; Alexander Speer; Wilbert Bitter; Tom N. Grossmann; Jan N. M. Commandeur Pubblicato in: Biochemical Pharmacology, Issue 1, 2020, ISSN 0006-2952 Editore: Elsevier BV DOI: 10.1016/j.bcp.2020.113938 Bicyclic β-Sheet Mimetics that Target the Transcriptional Coactivator β-Catenin and Inhibit Wnt Signaling Autori: Wendt, Mathias; Bellavita, Rosa; Gerber, Alan; Efrém, Nina‐Louisa; van Ramshorst, Thirza; Pearce, Nicholas M.; Davey, Paul R. J.; Everard, Isabel; Vazquez‐Chantada, Mercedes; Chiarparin, Elisabetta; Grieco, Paolo; Hennig, Sven; Grossmann, Tom N. Pubblicato in: Angewandte Chemie International Edition in English, n/a(n/a). John Wiley and Sons Ltd, Issue 2, 2021, ISSN 1433-7851 Editore: John Wiley & Sons Ltd. DOI: 10.1002/ange.202102082 Cell Permeable Stapled Peptide Inhibitor of Wnt Signaling that Targets β-Catenin Protein-Protein Interactions Autori: Laura Dietrich, Bernd Rathmer, Kenneth Ewan, Tanja Bange, Stefan Heinrichs, Trevor C. Dale, Dennis Schade, Tom N. Grossmann Pubblicato in: Cell Chemical Biology, Issue 24/8, 2017, Page(s) 958-968.e5, ISSN 2451-9456 Editore: Cell Press DOI: 10.1016/j.chembiol.2017.06.013 Structure-Based Design of Non-Natural Macrocyclic Peptides that Inhibit Protein-Protein Interactions Autori: Dennis M. Krüger, Adrian Glas, David Bier, Nicole Pospiech, Kerstin Wallraven, Laura Dietrich, Christian Ottmann, Oliver Koch, Sven Hennig, Tom N. Grossmann Pubblicato in: Journal of Medicinal Chemistry, 2017, ISSN 0022-2623 Editore: American Chemical Society DOI: 10.1021/acs.jmedchem.7b01221 Constraining an Irregular Peptide Secondary Structure through Ring-Closing Alkyne Metathesis Autori: Philipp M. Cromm, Kerstin Wallraven, Adrian Glas, David Bier, Alois Fürstner, Christian Ottmann, Tom N. Grossmann Pubblicato in: ChemBioChem, Issue 17/20, 2016, Page(s) 1915-1919, ISSN 1439-4227 Editore: John Wiley & Sons Ltd. DOI: 10.1002/cbic.201600362 Increased Conformational Flexibility of a Macrocycle-Receptor Complex Contributes to Reduced Dissociation Rates Autori: Adrian Glas, Eike-Christian Wamhoff, Dennis M. Krüger, Christoph Rademacher, Tom N. Grossmann Pubblicato in: Chemistry - A European Journal, 2017, ISSN 0947-6539 Editore: John Wiley & Sons Ltd. DOI: 10.1002/chem.201702776 In Situ Cyclization of Native Proteins: Structure-Based Design of a Bicyclic Enzyme Autori: Marta Pelay-Gimeno, Tanja Bange, Sven Hennig, Tom N. Grossmann Pubblicato in: Angewandte Chemie, Issue 130/35, 2018, Page(s) 11334-11340, ISSN 0044-8249 Editore: John Wiley & Sons Ltd. DOI: 10.1002/ange.201804506 Protein–RNA interactions: structural characteristics and hotspot amino acids Autori: Dennis M. Krüger, Saskia Neubacher, Tom N. Grossmann Pubblicato in: RNA, Issue 24/11, 2018, Page(s) 1457-1465, ISSN 1355-8382 Editore: Cold Spring Harbor Laboratory Press DOI: 10.1261/rna.066464.118 Coiled-Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection Autori: Carolin Mueller, Tom N. Grossmann Pubblicato in: Angewandte Chemie International Edition, Issue 57/52, 2018, Page(s) 17079-17083, ISSN 1433-7851 Editore: John Wiley & Sons Ltd. DOI: 10.1002/anie.201811515 Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119 Autori: Cromm, Philipp M.; Adihou, Hélène; Kapoor, Shobhna; Vazquez‐Chantada, Mercedes; Davey, Paul; Longmire, David; Hennes, Elisabeth; Hofer, Walter; Küchler, Philipp; Chiarparin, Elisabetta; Waldmann, Herbert; Grossmann, Tom N. Pubblicato in: ChemBioChem, 20(24), 2987 - 2990., 2019, ISSN 1439-7633 Editore: Wiley VCH DOI: 10.1002/cbic.201900615 Adapting free energy perturbation simulations for large macrocyclic ligands: how to dissect contributions from direct binding and free ligand flexibility† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc04705k Autori: Wallraven, Kerstin; Holmelin, Fredrik L.; Glas, Adrian; Hennig, Sven; Frolov, Andrey I.; Grossmann, Tom N. Pubblicato in: Chemical Science, 2020, ISSN 2041-6539 Editore: RSC DOI: 10.1039/c9sc04705k È in corso la ricerca di dati su OpenAIRE... Si è verificato un errore durante la ricerca dei dati su OpenAIRE Nessun risultato disponibile
