New approaches to characterise Schistosoma mansoni infections persisting despite mass drug administration

Informazioni relative al progetto

SCHISTO_PERSIST

ID dell’accordo di sovvenzione: 680088

DOI

10.3030/680088

Progetto chiuso

Data della firma CE 20 Gennaio 2016

Data di avvio 1 Aprile 2016

Data di completamento 30 Settembre 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 490 270,00

Contributo UE

€ 1 490 270,00

Coordinato da

UNIVERSITY OF GLASGOW
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (32)

Diagnosis of helminths depends on worm fecundity and the distribution of parasites within hosts

Autori: Thomas Crellen, Melissa Haswell, Paiboon Sithithaworn, Somphou Sayasone, Peter Odermatt, Poppy H. L. Lamberton, Simon E. F. Spencer and T. Déirdre Hollingsworth
Pubblicato in: Proceedings of the Royal Society B: Biological Sciences, 2023, ISSN 1471-2954
Editore: Royal Society
DOI: 10.1098/rspb.2022.2204

Monitoring schistosomiasis and sanitation interventions—The potential of environmental DNA

Autori: Teteh S. Champion, Stephanie Connelly, Cindy J. Smith, Poppy H. L. Lamberton
Pubblicato in: WIREs Water, Numero 8/1, 2021, ISSN 2049-1948
Editore: Wiley
DOI: 10.1002/wat2.1491

Public Health Policy Pillars for the Sustainable Elimination of Zoonotic Schistosomiasis

Autori: Eva Janoušková; Jessica Clark; Olumayowa Kajero; Sergi Alonso; Poppy H. L. Lamberton; Martha Betson; Joaquín M. Prada
Pubblicato in: Frontiers in Tropical Diseases, 2022, ISSN 2673-7515
Editore: Frontiers
DOI: 10.3389/fitd.2022.826501

Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration

Autori: Thomas Crellen, Martin Walker, Poppy H. L. Lamberton, Narcis B. Kabatereine, Edridah M. Tukahebwa, James A. Cotton, Joanne P. Webster
Pubblicato in: Clinical Infectious Diseases, 2016, ISSN 1058-4838
Editore: University of Chicago Press
DOI: 10.1093/cid/ciw506

Schistosomiasis Control: Leave No Age Group Behind

Autori: Christina L. Faust, Derick N.M. Osakunor, Jennifer A. Downs, Sekeleghe Kayuni, J. Russell Stothard, Poppy H.L. Lamberton, Jutta Reinhard-Rupp, David Rollinson
Pubblicato in: Trends in Parasitology, Numero 36/7, 2020, Pagina/e 582-591, ISSN 1471-4922
Editore: Elsevier BV
DOI: 10.1016/j.pt.2020.04.012

Using choice modelling to identify popular and affordable alternative interventions for schistosomiasis in Uganda

Autori: Keila Meginnis; Nick Hanley; Lazaaro Mujumbusi; Lucy Pickering; Poppy H. L. Lamberton
Pubblicato in: Environment and Development Economics, 2022, ISSN 1355-770X
Editore: Cambridge University Press
DOI: 10.1017/s1355770x22000079

Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration

Autori: Duncan J. Berger, Thomas Crellen, Poppy H. L. Lamberton, Fiona Allan, Alan Tracey, Jennifer D. Noonan, Narcis B. Kabatereine, Edridah M. Tukahebwa, Moses Adriko, Nancy Holroyd, Joanne P. Webster, Matthew Berriman, James A. Cotton
Pubblicato in: Nature Communications, Numero 12/1, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-24958-0

Reconciling Egg- and Antigen-Based Estimates of Schistosoma mansoni Clearance and Reinfection: A Modeling Study

Autori: Jessica Clark, Arinaitwe Moses, Andrina Nankasi, Christina L Faust, Adriko Moses, Diana Ajambo, Fred Besigye, Aaron Atuhaire, Aidah Wamboko, Lauren V Carruthers, Rachel Francoeur, Edridah M Tukahebwa, Joaquin M Prada, Poppy H L Lamberton
Pubblicato in: Clinical Infectious Diseases, 2021, ISSN 1058-4838
Editore: University of Chicago Press
DOI: 10.1093/cid/ciab679

Meta-analysis of variable-temperature PCR technique performance for diagnosising Schistosoma japonicum infections in humans in endemic areas

Autori: Meng-Tao Sun; Man-Man Gu; Jie-Ying Zhang; Qiu-Fu Yu; Poppy H. L. Lamberton; Da-Bing Lu
Pubblicato in: PLoS Neglected Tropical Diseases, 2022, ISSN 1935-2735
Editore: PloS
DOI: 10.1371/journal.pntd.0010136

Schistosomiasis messaging in endemic communities: Lessons and implications for interventions from rural Uganda, a rapid ethnographic assessment study

Autori: Agnes Ssali, Lucy Pickering, Edith Nalwadda, Lazaaro Mujumbusi, Janet Seeley, Poppy H. L. Lamberton
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 15/10, 2021, Pagina/e e0009893, ISSN 1935-2735
Editore: PLOS
DOI: 10.1371/journal.pntd.0009893

Non-monetary numeraires: Varying the payment vehicle in a choice experiment for health interventions in Uganda

Autori: Keila Meginnis, Nick Hanley, Lazaaro Mujumbusi, Poppy H.L. Lamberton
Pubblicato in: Ecological Economics, 2020, ISSN 0921-8009
Editore: Elsevier BV
DOI: 10.1016/j.ecolecon.2019.106569

Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme

Autori: Charlotte M. Gower, Florian Gehre, Sara R. Marques, Poppy H. L. Lamberton, Nicholas J. Lwambo & Joanne P. Webster
Pubblicato in: Parasites & Vectors, 2017, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-017-2533-6

Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autori: Suzan C. M. Trienekens; Christina L. Faust; Fred Besigye; Lucy Pickering; Edridah M. Tukahebwa; Janet Seeley; Poppy H. L. Lamberton
Pubblicato in: Parasites & Vectors, Numero 5, 2022, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-021-05121-6

MOESM1 of Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda

Autori: Faust, Christina; Crotti, Marco; Arinaitwe Moses; Oguttu, David; Aidah Wamboko; Adriko, Moses; Adekanle, Elizabeth; Kabatereine, Narcis; Edridah Tukahebwa; Norton, Alice; Gower, Charlotte; Webster, Joanne; Lamberton, Poppy
Pubblicato in: Parasites & Vectors, Numero 1, 2019, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.6084/m9.figshare.11471316

Impacts of host gender on Schistosoma mansoni risk in rural Uganda—A mixed-methods approach

Autori: Suzan C. M. Trienekens, Christina L. Faust, Keila Meginnis, Lucy Pickering, Olivia Ericsson, Andrina Nankasi, Arinaitwe Moses, Edridah M. Tukahebwa, Poppy H. L. Lamberton
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 14/5, 2020, Pagina/e e0008266, ISSN 1935-2735
Editore: Public Library of Science
DOI: 10.1371/journal.pntd.0008266

Soil-transmitted helminth infections

Autori: Peter Mark Jourdan, Poppy H L Lamberton, Alan Fenwick, David G Addiss
Pubblicato in: The Lancet, 2017, ISSN 0140-6736
Editore: The Lancet Publishing Group
DOI: 10.1016/S0140-6736(17)31930-X

The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni

Autori: Mafalda Viana, Christina L. Faust, Daniel T. Haydon, Joanne P. Webster, Poppy H. L. Lamberton
Pubblicato in: Evolutionary Applications, 2017, ISSN 1752-4571
Editore: Wiley Online
DOI: 10.1111/eva.12558

Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

Autori: Poppy H.L. Lamberton, Christina L. Faust, Joanne P. Webster
Pubblicato in: Infectious Diseases of Poverty, Numero 6/1, 2017, Pagina/e 110, ISSN 2049-9957
Editore: BioMed Central
DOI: 10.1186/s40249-017-0324-0

Understanding the relationship between egg- and antigen-based diagnostics of Schistosoma mansoni infection pre- and post-treatment in Uganda

Autori: Joaquín M. Prada, Panayiota Touloupou, Moses Adriko, Edridah M. Tukahebwa, Poppy H. L. Lamberton, T. Déirdre Hollingsworth
Pubblicato in: Parasites & Vectors, Numero 11/1, 2018, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-017-2580-z

Low Praziquantel Treatment Coverage for Schistosoma mansoni in Mayuge District, Uganda, Due to the Absence of Treatment Opportunities, Rather Than Systematic Non-Compliance

Autori: Moses Adriko, Christina Faust, Lauren Carruthers, Arinaitwe Moses, Edridah Tukahebwa, Poppy Lamberton
Pubblicato in: Tropical Medicine and Infectious Disease, Numero 3/4, 2018, Pagina/e 111, ISSN 2414-6366
Editore: MDPI
DOI: 10.3390/tropicalmed3040111

A Call for Systems Epidemiology to Tackle the Complexity of Schistosomiasis, Its Control, and Its Elimination

Autori: Stefanie Krauth, Julie Balen, Geoffrey Gobert, Poppy Lamberton
Pubblicato in: Tropical Medicine and Infectious Disease, Numero 4/1, 2019, Pagina/e 21, ISSN 2414-6366
Editore: MDPI
DOI: 10.3390/tropicalmed4010021

Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda

Autori: Christina L. Faust, Marco Crotti, Arinaitwe Moses, David Oguttu, Aidah Wamboko, Moses Adriko, Elizabeth K. Adekanle, Narcis Kabatereine, Edridah M. Tukahebwa, Alice J. Norton, Charlotte M. Gower, Joanne P. Webster, Poppy H. L. Lamberton
Pubblicato in: Parasites & Vectors, Numero 12/1, 2019, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-019-3860-6

The impact of storage conditions on human stool 16S rRNA microbiome composition and diversity

Autori: Lauren V. Carruthers, Arinaitwe Moses, Moses Adriko, Christina L. Faust, Edridah M. Tukahebwa, Lindsay J. Hall, Lisa C. Ranford-Cartwright, Poppy H.L. Lamberton
Pubblicato in: PeerJ, Numero 7, 2019, Pagina/e e8133, ISSN 2167-8359
Editore: PeerJ
DOI: 10.7717/peerj.8133

Strongyloides stercoralis: the need for accurate information – Authors' reply

Autori: Peter M Jourdan, Poppy H L Lamberton, Alan Fenwick, David G Addiss
Pubblicato in: The Lancet, Numero 391/10137, 2018, Pagina/e 2323, ISSN 0140-6736
Editore: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(18)30858-4

Defining schistosomiasis hotspots based on literature and shareholder interviews

Autori: Rivka M. Lim; Thomas M. Arme; Amy B. Pedersen; Joanne P. Webster; Poppy H.L. Lamberton
Pubblicato in: Trends in Parasitology, 2023, ISSN 1471-5007
Editore: Cell Press
DOI: 10.1016/j.pt.2023.09.006

ABO Blood Groups Do Not Predict Schistosoma mansoni Infection Profiles in Highly Endemic Villages of Uganda

Autori: Rachel Francoeur; Alon Atuhaire; Moses Arinaitwe; Moses Adriko; Diana Ajambo; Andrina Nankasi; Simon A. Babayan; Poppy H. L. Lamberton
Pubblicato in: Microorganisms, Vol 9, Iss 2448, p 2448 (2021), Numero 3, 2022, ISSN 2076-2607
Editore: MDPI
DOI: 10.3390/microorganisms9122448

Harnessing technology and portability to conduct molecular epidemiology of endemic pathogens in resource-limited settings

Autori: Christina L Faust, Kirstyn Brunker, Diana Ajambo, Mary Ryan, Arinaitwe Moses, Candia Rowel, Robert Mandela Wangoola, Eddie M Wampande, Andrew Guma, Moses Adriko, Poppy H L Lamberton, Edridah M Tukahebwa, Albert Mugenyi, Charles Waiswa
Pubblicato in: Transactions of The Royal Society of Tropical Medicine and Hygiene, 2020, ISSN 0035-9203
Editore: Royal Society of Tropical Medicine and Hygiene
DOI: 10.1093/trstmh/traa086

Understanding perceptions of schistosomiasis and its control among highly endemic lakeshore communities in Mayuge, Uganda

Autori: Lazaaro Mujumbusi; Edith Nalwadda; Agnes Ssali; Lucy Pickering; Janet Seeley; Keila Meginnis; Poppy H. L. Lamberton
Pubblicato in: PLoS Neglected Tropical Diseases, Numero 1, 2023, ISSN 1935-2735
Editore: PLoS
DOI: 10.1371/journal.pntd.0010687

Translating From Egg- to Antigen-Based Indicators for Schistosoma mansoni Elimination Targets: A Bayesian Latent Class Analysis Study

Autori: Clark, Jessica; Moses, Arinaitwe; Nankasi, Andrina; Faust, Christina L.; Adriko, Moses; Ajambo, Diana; Besigye, Fred; Atuhaire, Arron; Wamboko, Aidah; Rowel, Candia; Carruthers, Lauren V.; Francoeur, Rachel; Tukahebwa, Edridah M.; Lamberton, Poppy H.L.; Prada, Joaquin M.
Pubblicato in: Frontiers in Tropical Medicine, 2022, ISSN 2673-7515
Editore: Frontiers Media SA
DOI: 10.3389/fitd.2022.825721

Residence Time, Water Contact, and Age-driven Schistosoma mansoni Infection in Hotspot Communities in Uganda

Autori: Moses Arinaitwe, Moses Adriko, Brian Kibwika, Edridah M. Tukahebwa, Christina L. Faust, Poppy H. L. Lamberton
Pubblicato in: The American Journal of Tropical Medicine and Hygiene, 2021, ISSN 0002-9637
Editore: American Society of Tropical Medicine and Hygiene
DOI: 10.4269/ajtmh.21-0391

Gender-related differences in prevalence, intensity and associated risk factors of Schistosoma infections in Africa: A systematic review and meta-analysis

Autori: Diepreye Victoria Ayabina ,Jessica Clark,Helena Bayley,Poppy H. L. Lamberton,Jaspreet Toor ,T. Deirdre Hollingsworth
Pubblicato in: PLoS Neglected Tropical Diseases, 2021, ISSN 1935-2735
Editore: PLoS
DOI: 10.1371/journal.pntd.0009083

Reproducibility matters: intra- and inter-sample variation of the point-of-care circulating cathodic antigen test in two Schistosoma mansoni endemic areas in Uganda

Autori: Elías Kabbas-Piñango, Moses Arinaitwe, Govert J. van Dam, Adriko Moses, Annet Namukuta, Andrina Barungi Nankasi, Nicholas Khayinja Mwima, Fred Besigye, Joaquin M. Prada and Poppy H. L. Lamberton
Pubblicato in: Philosophical Transactions of the Royal Society B: Biological Sciences, 2023, ISSN 0962-8436
Editore: Royal Society of London
DOI: 10.1098/rstb.2022.0275

Other (9)

Additional file 2: of Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

Autori: Lamberton, Poppy; Faust, Christina; Webster, Joanne
Pubblicato in: Infectious Diseases of Poverty, Numero 4, 2017, ISSN 2049-9957
Editore: BMC
DOI: 10.6084/m9.figshare.c.3805381_d2

Additional file 3 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autori: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Pubblicato in: Parasites & Vectors, 2022
Editore: BMC
DOI: 10.6084/m9.figshare.17982983.v1

Additional file 1: of Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

Autori: Lamberton, Poppy; Faust, Christina; Webster, Joanne
Pubblicato in: Infectious Diseases of Poverty, Numero 4, 2017, ISSN 2049-9957
Editore: BMC
DOI: 10.6084/m9.figshare.c.3805381_d1.v1

Additional file 2: of Understanding the relationship between egg- and antigen-based diagnostics of Schistosoma mansoni infection pre- and post-treatment in Uganda

Autori: JoaquĂ­N Prada; Touloupou, Panayiota; Adriko, Moses; Edridah Tukahebwa; Lamberton, Poppy; T. DĂŠirdre Hollingsworth
Pubblicato in: Parasites & Vectors, Numero 2, 2018, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.6084/m9.figshare.5768751.v1

Additional file 5 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autori: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Pubblicato in: Parasites & Vectors, 2022
Editore: BMC
DOI: 10.6084/m9.figshare.17982992

Additional file 2 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autori: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Pubblicato in: Parasites & Vectors, Numero 1, 2022
Editore: BMC
DOI: 10.6084/m9.figshare.17982980.v1

Additional file 1 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autori: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Pubblicato in: Trienekens, Suzan C. M.; Faust, Christina L., 2022
Editore: BMC
DOI: 10.6084/m9.figshare.17982977.v1

Additional file 1: of Understanding the relationship between egg- and antigen-based diagnostics of Schistosoma mansoni infection pre- and post-treatment in Uganda

Autori: JoaquĂ­N Prada; Touloupou, Panayiota; Adriko, Moses; Edridah Tukahebwa; Lamberton, Poppy; T. DĂŠirdre Hollingsworth
Pubblicato in: Parasites & Vectors, Numero 1, 2018, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.6084/m9.figshare.5768736

Additional file 4 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autori: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Pubblicato in: Numero 2, 2022, ISSN 1756-3305
Editore: BMC
DOI: 10.6084/m9.figshare.17982989

Non-peer reviewed articles (2)

Wicked-Schisto: The wicked public health problem of Schistosomiasis and the interdisciplinary research helping to control it

Autori: Poppy Lamberton
Pubblicato in: Open Access Government, 2022, ISSN 2516-3817
Editore: Open Access Government
DOI: 10.56367/oag-037-10604

Schistosomiasis solution is not as simple as mass drug administration: Lamberton Lab takes a holistic approach to break the cycle of infection

Autori: Poppy Lamberton
Pubblicato in: The Project Repository Journal Volume 14, 2022, ISSN 2632-4067
Editore: European Dissemination Media Agency
DOI: 10.54050/prj1419274