New approaches to characterise Schistosoma mansoni infections persisting despite mass drug administration

Informacje na temat projektu

SCHISTO_PERSIST

Identyfikator umowy o grant: 680088

DOI

10.3030/680088

Projekt został zamknięty

Data podpisania przez KE 20 Stycznia 2016

Data rozpoczęcia 1 Kwietnia 2016

Data zakończenia 30 Września 2023

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 1 490 270,00

Wkład UE

€ 1 490 270,00

Koordynowany przez

UNIVERSITY OF GLASGOW
United Kingdom

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Peer reviewed articles (32)

Diagnosis of helminths depends on worm fecundity and the distribution of parasites within hosts

Autorzy: Thomas Crellen, Melissa Haswell, Paiboon Sithithaworn, Somphou Sayasone, Peter Odermatt, Poppy H. L. Lamberton, Simon E. F. Spencer and T. Déirdre Hollingsworth
Opublikowane w: Proceedings of the Royal Society B: Biological Sciences, 2023, ISSN 1471-2954
Wydawca: Royal Society
DOI: 10.1098/rspb.2022.2204

Monitoring schistosomiasis and sanitation interventions—The potential of environmental DNA

Autorzy: Teteh S. Champion, Stephanie Connelly, Cindy J. Smith, Poppy H. L. Lamberton
Opublikowane w: WIREs Water, Numer 8/1, 2021, ISSN 2049-1948
Wydawca: Wiley
DOI: 10.1002/wat2.1491

Public Health Policy Pillars for the Sustainable Elimination of Zoonotic Schistosomiasis

Autorzy: Eva Janoušková; Jessica Clark; Olumayowa Kajero; Sergi Alonso; Poppy H. L. Lamberton; Martha Betson; Joaquín M. Prada
Opublikowane w: Frontiers in Tropical Diseases, 2022, ISSN 2673-7515
Wydawca: Frontiers
DOI: 10.3389/fitd.2022.826501

Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration

Autorzy: Thomas Crellen, Martin Walker, Poppy H. L. Lamberton, Narcis B. Kabatereine, Edridah M. Tukahebwa, James A. Cotton, Joanne P. Webster
Opublikowane w: Clinical Infectious Diseases, 2016, ISSN 1058-4838
Wydawca: University of Chicago Press
DOI: 10.1093/cid/ciw506

Schistosomiasis Control: Leave No Age Group Behind

Autorzy: Christina L. Faust, Derick N.M. Osakunor, Jennifer A. Downs, Sekeleghe Kayuni, J. Russell Stothard, Poppy H.L. Lamberton, Jutta Reinhard-Rupp, David Rollinson
Opublikowane w: Trends in Parasitology, Numer 36/7, 2020, Strona(/y) 582-591, ISSN 1471-4922
Wydawca: Elsevier BV
DOI: 10.1016/j.pt.2020.04.012

Using choice modelling to identify popular and affordable alternative interventions for schistosomiasis in Uganda

Autorzy: Keila Meginnis; Nick Hanley; Lazaaro Mujumbusi; Lucy Pickering; Poppy H. L. Lamberton
Opublikowane w: Environment and Development Economics, 2022, ISSN 1355-770X
Wydawca: Cambridge University Press
DOI: 10.1017/s1355770x22000079

Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration

Autorzy: Duncan J. Berger, Thomas Crellen, Poppy H. L. Lamberton, Fiona Allan, Alan Tracey, Jennifer D. Noonan, Narcis B. Kabatereine, Edridah M. Tukahebwa, Moses Adriko, Nancy Holroyd, Joanne P. Webster, Matthew Berriman, James A. Cotton
Opublikowane w: Nature Communications, Numer 12/1, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-24958-0

Reconciling Egg- and Antigen-Based Estimates of Schistosoma mansoni Clearance and Reinfection: A Modeling Study

Autorzy: Jessica Clark, Arinaitwe Moses, Andrina Nankasi, Christina L Faust, Adriko Moses, Diana Ajambo, Fred Besigye, Aaron Atuhaire, Aidah Wamboko, Lauren V Carruthers, Rachel Francoeur, Edridah M Tukahebwa, Joaquin M Prada, Poppy H L Lamberton
Opublikowane w: Clinical Infectious Diseases, 2021, ISSN 1058-4838
Wydawca: University of Chicago Press
DOI: 10.1093/cid/ciab679

Meta-analysis of variable-temperature PCR technique performance for diagnosising Schistosoma japonicum infections in humans in endemic areas

Autorzy: Meng-Tao Sun; Man-Man Gu; Jie-Ying Zhang; Qiu-Fu Yu; Poppy H. L. Lamberton; Da-Bing Lu
Opublikowane w: PLoS Neglected Tropical Diseases, 2022, ISSN 1935-2735
Wydawca: PloS
DOI: 10.1371/journal.pntd.0010136

Schistosomiasis messaging in endemic communities: Lessons and implications for interventions from rural Uganda, a rapid ethnographic assessment study

Autorzy: Agnes Ssali, Lucy Pickering, Edith Nalwadda, Lazaaro Mujumbusi, Janet Seeley, Poppy H. L. Lamberton
Opublikowane w: PLOS Neglected Tropical Diseases, Numer 15/10, 2021, Strona(/y) e0009893, ISSN 1935-2735
Wydawca: PLOS
DOI: 10.1371/journal.pntd.0009893

Non-monetary numeraires: Varying the payment vehicle in a choice experiment for health interventions in Uganda

Autorzy: Keila Meginnis, Nick Hanley, Lazaaro Mujumbusi, Poppy H.L. Lamberton
Opublikowane w: Ecological Economics, 2020, ISSN 0921-8009
Wydawca: Elsevier BV
DOI: 10.1016/j.ecolecon.2019.106569

Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme

Autorzy: Charlotte M. Gower, Florian Gehre, Sara R. Marques, Poppy H. L. Lamberton, Nicholas J. Lwambo & Joanne P. Webster
Opublikowane w: Parasites & Vectors, 2017, ISSN 1756-3305
Wydawca: BioMed Central
DOI: 10.1186/s13071-017-2533-6

Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autorzy: Suzan C. M. Trienekens; Christina L. Faust; Fred Besigye; Lucy Pickering; Edridah M. Tukahebwa; Janet Seeley; Poppy H. L. Lamberton
Opublikowane w: Parasites & Vectors, Numer 5, 2022, ISSN 1756-3305
Wydawca: BioMed Central
DOI: 10.1186/s13071-021-05121-6

MOESM1 of Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda

Autorzy: Faust, Christina; Crotti, Marco; Arinaitwe Moses; Oguttu, David; Aidah Wamboko; Adriko, Moses; Adekanle, Elizabeth; Kabatereine, Narcis; Edridah Tukahebwa; Norton, Alice; Gower, Charlotte; Webster, Joanne; Lamberton, Poppy
Opublikowane w: Parasites & Vectors, Numer 1, 2019, ISSN 1756-3305
Wydawca: BioMed Central
DOI: 10.6084/m9.figshare.11471316

Impacts of host gender on Schistosoma mansoni risk in rural Uganda—A mixed-methods approach

Autorzy: Suzan C. M. Trienekens, Christina L. Faust, Keila Meginnis, Lucy Pickering, Olivia Ericsson, Andrina Nankasi, Arinaitwe Moses, Edridah M. Tukahebwa, Poppy H. L. Lamberton
Opublikowane w: PLOS Neglected Tropical Diseases, Numer 14/5, 2020, Strona(/y) e0008266, ISSN 1935-2735
Wydawca: Public Library of Science
DOI: 10.1371/journal.pntd.0008266

Soil-transmitted helminth infections

Autorzy: Peter Mark Jourdan, Poppy H L Lamberton, Alan Fenwick, David G Addiss
Opublikowane w: The Lancet, 2017, ISSN 0140-6736
Wydawca: The Lancet Publishing Group
DOI: 10.1016/S0140-6736(17)31930-X

The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni

Autorzy: Mafalda Viana, Christina L. Faust, Daniel T. Haydon, Joanne P. Webster, Poppy H. L. Lamberton
Opublikowane w: Evolutionary Applications, 2017, ISSN 1752-4571
Wydawca: Wiley Online
DOI: 10.1111/eva.12558

Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

Autorzy: Poppy H.L. Lamberton, Christina L. Faust, Joanne P. Webster
Opublikowane w: Infectious Diseases of Poverty, Numer 6/1, 2017, Strona(/y) 110, ISSN 2049-9957
Wydawca: BioMed Central
DOI: 10.1186/s40249-017-0324-0

Understanding the relationship between egg- and antigen-based diagnostics of Schistosoma mansoni infection pre- and post-treatment in Uganda

Autorzy: Joaquín M. Prada, Panayiota Touloupou, Moses Adriko, Edridah M. Tukahebwa, Poppy H. L. Lamberton, T. Déirdre Hollingsworth
Opublikowane w: Parasites & Vectors, Numer 11/1, 2018, ISSN 1756-3305
Wydawca: BioMed Central
DOI: 10.1186/s13071-017-2580-z

Low Praziquantel Treatment Coverage for Schistosoma mansoni in Mayuge District, Uganda, Due to the Absence of Treatment Opportunities, Rather Than Systematic Non-Compliance

Autorzy: Moses Adriko, Christina Faust, Lauren Carruthers, Arinaitwe Moses, Edridah Tukahebwa, Poppy Lamberton
Opublikowane w: Tropical Medicine and Infectious Disease, Numer 3/4, 2018, Strona(/y) 111, ISSN 2414-6366
Wydawca: MDPI
DOI: 10.3390/tropicalmed3040111

A Call for Systems Epidemiology to Tackle the Complexity of Schistosomiasis, Its Control, and Its Elimination

Autorzy: Stefanie Krauth, Julie Balen, Geoffrey Gobert, Poppy Lamberton
Opublikowane w: Tropical Medicine and Infectious Disease, Numer 4/1, 2019, Strona(/y) 21, ISSN 2414-6366
Wydawca: MDPI
DOI: 10.3390/tropicalmed4010021

Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda

Autorzy: Christina L. Faust, Marco Crotti, Arinaitwe Moses, David Oguttu, Aidah Wamboko, Moses Adriko, Elizabeth K. Adekanle, Narcis Kabatereine, Edridah M. Tukahebwa, Alice J. Norton, Charlotte M. Gower, Joanne P. Webster, Poppy H. L. Lamberton
Opublikowane w: Parasites & Vectors, Numer 12/1, 2019, ISSN 1756-3305
Wydawca: BioMed Central
DOI: 10.1186/s13071-019-3860-6

The impact of storage conditions on human stool 16S rRNA microbiome composition and diversity

Autorzy: Lauren V. Carruthers, Arinaitwe Moses, Moses Adriko, Christina L. Faust, Edridah M. Tukahebwa, Lindsay J. Hall, Lisa C. Ranford-Cartwright, Poppy H.L. Lamberton
Opublikowane w: PeerJ, Numer 7, 2019, Strona(/y) e8133, ISSN 2167-8359
Wydawca: PeerJ
DOI: 10.7717/peerj.8133

Strongyloides stercoralis: the need for accurate information – Authors' reply

Autorzy: Peter M Jourdan, Poppy H L Lamberton, Alan Fenwick, David G Addiss
Opublikowane w: The Lancet, Numer 391/10137, 2018, Strona(/y) 2323, ISSN 0140-6736
Wydawca: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(18)30858-4

Defining schistosomiasis hotspots based on literature and shareholder interviews

Autorzy: Rivka M. Lim; Thomas M. Arme; Amy B. Pedersen; Joanne P. Webster; Poppy H.L. Lamberton
Opublikowane w: Trends in Parasitology, 2023, ISSN 1471-5007
Wydawca: Cell Press
DOI: 10.1016/j.pt.2023.09.006

ABO Blood Groups Do Not Predict Schistosoma mansoni Infection Profiles in Highly Endemic Villages of Uganda

Autorzy: Rachel Francoeur; Alon Atuhaire; Moses Arinaitwe; Moses Adriko; Diana Ajambo; Andrina Nankasi; Simon A. Babayan; Poppy H. L. Lamberton
Opublikowane w: Microorganisms, Vol 9, Iss 2448, p 2448 (2021), Numer 3, 2022, ISSN 2076-2607
Wydawca: MDPI
DOI: 10.3390/microorganisms9122448

Harnessing technology and portability to conduct molecular epidemiology of endemic pathogens in resource-limited settings

Autorzy: Christina L Faust, Kirstyn Brunker, Diana Ajambo, Mary Ryan, Arinaitwe Moses, Candia Rowel, Robert Mandela Wangoola, Eddie M Wampande, Andrew Guma, Moses Adriko, Poppy H L Lamberton, Edridah M Tukahebwa, Albert Mugenyi, Charles Waiswa
Opublikowane w: Transactions of The Royal Society of Tropical Medicine and Hygiene, 2020, ISSN 0035-9203
Wydawca: Royal Society of Tropical Medicine and Hygiene
DOI: 10.1093/trstmh/traa086

Understanding perceptions of schistosomiasis and its control among highly endemic lakeshore communities in Mayuge, Uganda

Autorzy: Lazaaro Mujumbusi; Edith Nalwadda; Agnes Ssali; Lucy Pickering; Janet Seeley; Keila Meginnis; Poppy H. L. Lamberton
Opublikowane w: PLoS Neglected Tropical Diseases, Numer 1, 2023, ISSN 1935-2735
Wydawca: PLoS
DOI: 10.1371/journal.pntd.0010687

Translating From Egg- to Antigen-Based Indicators for Schistosoma mansoni Elimination Targets: A Bayesian Latent Class Analysis Study

Autorzy: Clark, Jessica; Moses, Arinaitwe; Nankasi, Andrina; Faust, Christina L.; Adriko, Moses; Ajambo, Diana; Besigye, Fred; Atuhaire, Arron; Wamboko, Aidah; Rowel, Candia; Carruthers, Lauren V.; Francoeur, Rachel; Tukahebwa, Edridah M.; Lamberton, Poppy H.L.; Prada, Joaquin M.
Opublikowane w: Frontiers in Tropical Medicine, 2022, ISSN 2673-7515
Wydawca: Frontiers Media SA
DOI: 10.3389/fitd.2022.825721

Residence Time, Water Contact, and Age-driven Schistosoma mansoni Infection in Hotspot Communities in Uganda

Autorzy: Moses Arinaitwe, Moses Adriko, Brian Kibwika, Edridah M. Tukahebwa, Christina L. Faust, Poppy H. L. Lamberton
Opublikowane w: The American Journal of Tropical Medicine and Hygiene, 2021, ISSN 0002-9637
Wydawca: American Society of Tropical Medicine and Hygiene
DOI: 10.4269/ajtmh.21-0391

Gender-related differences in prevalence, intensity and associated risk factors of Schistosoma infections in Africa: A systematic review and meta-analysis

Autorzy: Diepreye Victoria Ayabina ,Jessica Clark,Helena Bayley,Poppy H. L. Lamberton,Jaspreet Toor ,T. Deirdre Hollingsworth
Opublikowane w: PLoS Neglected Tropical Diseases, 2021, ISSN 1935-2735
Wydawca: PLoS
DOI: 10.1371/journal.pntd.0009083

Reproducibility matters: intra- and inter-sample variation of the point-of-care circulating cathodic antigen test in two Schistosoma mansoni endemic areas in Uganda

Autorzy: Elías Kabbas-Piñango, Moses Arinaitwe, Govert J. van Dam, Adriko Moses, Annet Namukuta, Andrina Barungi Nankasi, Nicholas Khayinja Mwima, Fred Besigye, Joaquin M. Prada and Poppy H. L. Lamberton
Opublikowane w: Philosophical Transactions of the Royal Society B: Biological Sciences, 2023, ISSN 0962-8436
Wydawca: Royal Society of London
DOI: 10.1098/rstb.2022.0275

Other (9)

Additional file 2: of Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

Autorzy: Lamberton, Poppy; Faust, Christina; Webster, Joanne
Opublikowane w: Infectious Diseases of Poverty, Numer 4, 2017, ISSN 2049-9957
Wydawca: BMC
DOI: 10.6084/m9.figshare.c.3805381_d2

Additional file 3 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autorzy: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Opublikowane w: Parasites & Vectors, 2022
Wydawca: BMC
DOI: 10.6084/m9.figshare.17982983.v1

Additional file 1: of Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study

Autorzy: Lamberton, Poppy; Faust, Christina; Webster, Joanne
Opublikowane w: Infectious Diseases of Poverty, Numer 4, 2017, ISSN 2049-9957
Wydawca: BMC
DOI: 10.6084/m9.figshare.c.3805381_d1.v1

Additional file 2: of Understanding the relationship between egg- and antigen-based diagnostics of Schistosoma mansoni infection pre- and post-treatment in Uganda

Autorzy: JoaquĂ­N Prada; Touloupou, Panayiota; Adriko, Moses; Edridah Tukahebwa; Lamberton, Poppy; T. DĂŠirdre Hollingsworth
Opublikowane w: Parasites & Vectors, Numer 2, 2018, ISSN 1756-3305
Wydawca: BioMed Central
DOI: 10.6084/m9.figshare.5768751.v1

Additional file 5 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autorzy: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Opublikowane w: Parasites & Vectors, 2022
Wydawca: BMC
DOI: 10.6084/m9.figshare.17982992

Additional file 2 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autorzy: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Opublikowane w: Parasites & Vectors, Numer 1, 2022
Wydawca: BMC
DOI: 10.6084/m9.figshare.17982980.v1

Additional file 1 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autorzy: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Opublikowane w: Trienekens, Suzan C. M.; Faust, Christina L., 2022
Wydawca: BMC
DOI: 10.6084/m9.figshare.17982977.v1

Additional file 1: of Understanding the relationship between egg- and antigen-based diagnostics of Schistosoma mansoni infection pre- and post-treatment in Uganda

Autorzy: JoaquĂ­N Prada; Touloupou, Panayiota; Adriko, Moses; Edridah Tukahebwa; Lamberton, Poppy; T. DĂŠirdre Hollingsworth
Opublikowane w: Parasites & Vectors, Numer 1, 2018, ISSN 1756-3305
Wydawca: BioMed Central
DOI: 10.6084/m9.figshare.5768736

Additional file 4 of Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity

Autorzy: Trienekens, Suzan C. M.; Faust, Christina L.; Besigye, Fred; Pickering, Lucy; Tukahebwa, Edridah M.; Seeley, Janet; Lamberton, Poppy H. L.
Opublikowane w: Numer 2, 2022, ISSN 1756-3305
Wydawca: BMC
DOI: 10.6084/m9.figshare.17982989

Non-peer reviewed articles (2)

Wicked-Schisto: The wicked public health problem of Schistosomiasis and the interdisciplinary research helping to control it

Autorzy: Poppy Lamberton
Opublikowane w: Open Access Government, 2022, ISSN 2516-3817
Wydawca: Open Access Government
DOI: 10.56367/oag-037-10604

Schistosomiasis solution is not as simple as mass drug administration: Lamberton Lab takes a holistic approach to break the cycle of infection

Autorzy: Poppy Lamberton
Opublikowane w: The Project Repository Journal Volume 14, 2022, ISSN 2632-4067
Wydawca: European Dissemination Media Agency
DOI: 10.54050/prj1419274