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Title of Proposal: Restoring the immune system homeostasis and organ function in severe community acquired pneumonia- induced sepsis through adipose derived allogeneic stem cells (SEPCELL Proje

Pubblicazioni

Human Adipose-Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae.

Autori: Perlee D, de Vos AF, Scicluna BP, Mancheño P, de la Rosa O, Dalemans W, Nürnberg P, Lombardo E, van der Poll T.
Pubblicato in: Stem Cells Transl Med., 2019, ISSN 2157-6564
Editore: AlphaMed Press

Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice.

Autori: Perlee, Desirée; de Vos, Alex F.; Scicluna, Brendon P.; Maag, Anja; Mancheño, Pablo; de la Rosa, Olga; Dalemans, Wilfried; Florquin, Sandrine; van’t Veer, Cornelis; Lombardo, Eleuterio; van der Poll, Tom
Pubblicato in: VOLUME=10;ISSUE=1;ISSN=1757-6512;TITLE=STEM CELL RESEARCH & THERAPY, Numero 1, 2019, Pagina/e 10(1):286, ISSN 1757-6512
Editore: BioMed Central
DOI: 10.1186/s13287-019-1391-x

A phase Ib/IIa, randomised, double-blind, multicentre trial to assess the safety and efficacy of expanded Cx611 allogeneic adipose-derived stem cells (eASCs) for the treatment of patients with community-acquired bacterial pneumonia admitted to the intensive care unit.

Autori: Laterre PF, Sánchez-García M, van der Poll T, de la Rosa O, Cadogan KA, Lombardo E, François B
Pubblicato in: BMC Pulm Med, 2020, Pagina/e 20(1):309, ISSN 1471-2466
Editore: BioMed Central
DOI: 10.1186/s12890-020-01324-2

Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2

Autori: Ortiz-Virumbrales M, Menta R, Pérez LM, Lucchesi O, Mancheño-Corvo P, Avivar-Valderas Á, Palacios I, Herrero-Mendez A, Dalemans W, de la Rosa O, Lombardo
Pubblicato in: Stem Cell Res Ther., 2020, Pagina/e 11(1):462, ISSN 1757-6512
Editore: BioMed Central
DOI: 10.1186/s13287-020-01975-2

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