Towards outstanding research and training in tumour biology at IMM

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

High Resolution Microscopy Workshop
EC Performance Indicators Widening indicator application for the 3-year window time prior to ReTuBi

EC Performance Indicators Widening indicator application for the 3-year window time prior to ReTuBi

Second edition of the High-Resolution Microscopy Workshop

A second edition of the High-Resolution Microscopy Workshop will be organized on M34 due to the successful implementation of the first edition, the successful accomplishment of the objectives and the growing demand from the partnering institutions on participating in these type of practical activity.

Second edition of the Career development and soft skills for young scientists

A second edition of thethe Career development and soft skills for young scientists – From Lisbon to the World Workshop will be organized on M26 due to the successful implementation of the first edition, the successful accomplishment of the objectives and the growing demand from the partnering institutions on participating in these type of practical activity.

Career development and soft skills for young scientists
Brochure and flyer

ReTuBi website and logo

Publications

CHK1 and replicative stress in T-cell leukemia: Can an irreverent tumor suppressor end up playing the oncogene?

Auteurs: Leonor M. Sarmento, João T. Barata
Publié dans: Advances in Biological Regulation, Numéro 60, 2016, Page(s) 115-121, ISSN 2212-4926
Éditeur: Elsevier BV
DOI: 10.1016/j.jbior.2015.10.007

Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor

Auteurs: Leila R. Martins, Yasser Perera, Paulo Lúcio, Maria G. Silva, Silvio E. Perea, João T. Barata
Publié dans: Oncotarget, Numéro 5/1, 2014, Page(s) 258-263, ISSN 1949-2553
Éditeur: Impact Journals
DOI: 10.18632/oncotarget.1513

CHK1 overexpression in T-cell acute lymphoblastic leukemia is essential for proliferation and survival by preventing excessive replication stress

Auteurs: L M Sarmento, V Póvoa, R Nascimento, G Real, I Antunes, L R Martins, C Moita, P M Alves, M Abecasis, L F Moita, R M E Parkhouse, J P P Meijerink, J T Barata
Publié dans: Oncogene, Numéro 34/23, 2014, Page(s) 2978-2990, ISSN 0950-9232
Éditeur: Nature Publishing Group
DOI: 10.1038/onc.2014.248

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

Auteurs: Irene Maria Aspalter, Emma Gordon, Alexandre Dubrac, Anan Ragab, Jarek Narloch, Pedro Vizán, Ilse Geudens, Russell Thomas Collins, Claudio Areias Franco, Cristina Luna Abrahams, Gavin Thurston, Marcus Fruttiger, Ian Rosewell, Anne Eichmann, Holger Gerhardt
Publié dans: Nature Communications, Numéro 6, 2015, Page(s) 7264, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/ncomms8264

Targeting bone metastases in prostate cancer: improving clinical outcome

Auteurs: Jean-Jacques Body, Sandra Casimiro, Luís Costa
Publié dans: Nature Reviews Urology, Numéro 12/6, 2015, Page(s) 340-356, ISSN 1759-4812
Éditeur: Nature Publishing Group
DOI: 10.1038/nrurol.2015.90

Computer simulations reveal complex distribution of haemodynamic forces in a mouse retina model of angiogenesis

Auteurs: M. O. Bernabeu, M. L. Jones, J. H. Nielsen, T. Kruger, R. W. Nash, D. Groen, S. Schmieschek, J. Hetherington, H. Gerhardt, C. A. Franco, P. V. Coveney
Publié dans: Journal of The Royal Society Interface, Numéro 11/99, 2014, Page(s) 20140543-20140543, ISSN 1742-5689
Éditeur: The Royal Society
DOI: 10.1098/rsif.2014.0543

Novel Insights into Breast Cancer Genetic Variance through RNA Sequencing

Auteurs: Anelia Horvath, Suresh Babu Pakala, Prakriti Mudvari, Sirigiri Divijendra Natha Reddy, Kazufumi Ohshiro, Sandra Casimiro, Ricardo Pires, Suzanne A. W. Fuqua, Masakazu Toi, Luis Costa, Sujit S. Nair, Saraswati Sukumar, Rakesh Kumar
Publié dans: Scientific Reports, Numéro 3, 2013, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/srep02256

LDL-cholesterol signaling induces breast cancer proliferation and invasion

Auteurs: Catarina Rodrigues dos Santos, Germana Domingues, Inês Matias, João Matos, Isabel Fonseca, José de Almeida, Sérgio Dias
Publié dans: Lipids in Health and Disease, Numéro 13/1, 2014, Page(s) 16, ISSN 1476-511X
Éditeur: BioMed Central
DOI: 10.1186/1476-511X-13-16

SRF selectively controls tip cell invasive behavior in angiogenesis

Auteurs: C. A. Franco, J. Blanc, A. Parlakian, R. Blanco, I. M. Aspalter, N. Kazakova, N. Diguet, E. Mylonas, J. Gao-Li, A. Vaahtokari, V. Penard-Lacronique, M. Fruttiger, I. Rosewell, M. Mericskay, H. Gerhardt, Z. Li
Publié dans: Development, Numéro 140/11, 2013, Page(s) 2321-2333, ISSN 0950-1991
Éditeur: The Company of Biologists Ltd.
DOI: 10.1242/dev.091074

A Unified Nomenclature and Amino Acid Numbering for Human PTEN

Auteurs: R. Pulido, S. J. Baker, J. T. Barata, A. Carracedo, V. J. Cid, I. D. Chin-Sang, V. Dave, J. den Hertog, P. Devreotes, B. J. Eickholt, C. Eng, F. B. Furnari, M.-M. Georgescu, A. Gericke, B. Hopkins, X. Jiang, S.-R. Lee, M. Losche, P. Malaney, X. Matias-Guiu, M. Molina, P. P. Pandolfi, R. Parsons, P. Pinton, C. Rivas, R. M. Rocha, M. S. Rodriguez, A. H. Ross, M. Serrano, V. Stambolic, B. Stiles, A. Suzuki, S.-S. Tan, N. K. Tonks, L. C. Trotman, N. Wolff, R. Woscholski, H. Wu, N. R. Leslie
Publié dans: Science Signaling, Numéro 7/332, 2014, Page(s) pe15-pe15, ISSN 1937-9145
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/scisignal.2005560

Heterogeneous lineage marker expression in naive embryonic stem cells is mostly due to spontaneous differentiation

Auteurs: Gautham Nair, Elsa Abranches, Ana M. V. Guedes, Domingos Henrique, Arjun Raj
Publié dans: Scientific Reports, Numéro 5, 2015, Page(s) 13339, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/srep13339

Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia

Auteurs: A Lonetti, I L Antunes, F Chiarini, E Orsini, F Buontempo, F Ricci, P L Tazzari, P Pagliaro, F Melchionda, A Pession, A Bertaina, F Locatelli, J A McCubrey, J T Barata, A M Martelli
Publié dans: Leukemia, Numéro 28/6, 2013, Page(s) 1196-1206, ISSN 0887-6924
Éditeur: Nature Publishing Group
DOI: 10.1038/leu.2013.369

Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency

Auteurs: E. Abranches, A. M. V. Guedes, M. Moravec, H. Maamar, P. Svoboda, A. Raj, D. Henrique
Publié dans: Development, Numéro 141/14, 2014, Page(s) 2770-2779, ISSN 0950-1991
Éditeur: The Company of Biologists Ltd.
DOI: 10.1242/dev.108910

PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events

Auteurs: R. D. Mendes, L. M. Sarmento, K. Cante-Barrett, L. Zuurbier, J. G. C. A. M. Buijs-Gladdines, V. Povoa, W. K. Smits, M. Abecasis, J. A. Yunes, E. Sonneveld, M. A. Horstmann, R. Pieters, J. T. Barata, J. P. P. Meijerink
Publié dans: Blood, Numéro 124/4, 2014, Page(s) 567-578, ISSN 0006-4971
Éditeur: American Society of Hematology
DOI: 10.1182/blood-2014-03-562751

Fast, Multi-Dimensional and Simultaneous Kymograph-Like Particle Dynamics (SkyPad) Analysis

Auteurs: Bruno Cadot, Vincent Gache, Edgar R. Gomes
Publié dans: PLoS ONE, Numéro 9/2, 2014, Page(s) e89073, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0089073

PTEN and leukemia stem cells

Auteurs: Rita Fragoso, João T. Barata
Publié dans: Advances in Biological Regulation, Numéro 56, 2014, Page(s) 22-29, ISSN 2212-4926
Éditeur: Elsevier BV
DOI: 10.1016/j.jbior.2014.05.005

Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression

Auteurs: Claudio A. Franco, Martin L. Jones, Miguel O. Bernabeu, Ilse Geudens, Thomas Mathivet, Andre Rosa, Felicia M. Lopes, Aida P. Lima, Anan Ragab, Russell T. Collins, Li-Kun Phng, Peter V. Coveney, Holger Gerhardt
Publié dans: PLOS Biology, Numéro 13/4, 2015, Page(s) e1002125, ISSN 1545-7885
Éditeur: PLOS
DOI: 10.1371/journal.pbio.1002125

Bone remodeling markers and bone metastases: From cancer research to clinical implications

Auteurs: Arlindo Ferreira, Irina Alho, Sandra Casimiro, Luís Costa
Publié dans: BoneKEy Reports, Numéro 4, 2015, Page(s) 668, ISSN 2047-6396
Éditeur: Nature Publishing Group
DOI: 10.1038/bonekey.2015.35

Notch Signalling Is Required for the Formation of Structurally Stable Muscle Fibres in Zebrafish

Auteurs: Susana Pascoal, Joana Esteves de Lima, Jonathan D. Leslie, Simon M. Hughes, Leonor Saúde
Publié dans: PLoS ONE, Numéro 8/6, 2013, Page(s) e68021, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0068021

Low Molecular Weight Protein Tyrosine Phosphatase Isoforms Regulate Breast Cancer Cells Migration through a RhoA Dependent Mechanism

Auteurs: Irina Alho, Luis Costa, Manuel Bicho, Constança Coelho
Publié dans: PLoS ONE, Numéro 8/9, 2013, Page(s) e76307, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0076307

miR-363-5p regulates endothelial cell properties and their communication with hematopoietic precursor cells

Auteurs: Ana Costa, Joana Afonso, Catarina Osório, Ana L Gomes, Francisco Caiado, Joana Valente, Sandra I Aguiar, Francisco Pinto, Mário Ramirez, Sérgio Dias
Publié dans: Journal of Hematology & Oncology, Numéro 6/1, 2013, Page(s) 87, ISSN 1756-8722
Éditeur: BioMed Central
DOI: 10.1186/1756-8722-6-87

Neuromesodermal progenitors and the making of the spinal cord

Auteurs: D. Henrique, E. Abranches, L. Verrier, K. G. Storey
Publié dans: Development, Numéro 142/17, 2015, Page(s) 2864-2875, ISSN 0950-1991
Éditeur: The Company of Biologists Ltd.
DOI: 10.1242/dev.119768

Kinases, tails and more: Regulation of PTEN function by phosphorylation

Auteurs: Rita Fragoso, João T. Barata
Publié dans: Methods, Numéro 77-78, 2015, Page(s) 75-81, ISSN 1046-2023
Éditeur: Academic Press
DOI: 10.1016/j.ymeth.2014.10.015

Glycogen Synthase Kinase-3 Inhibition Enhances Translation of Pluripotency-Associated Transcription Factors to Contribute to Maintenance of Mouse Embryonic Stem Cell Self-Renewal

Auteurs: Yolanda Sanchez-Ripoll, Heather K. Bone, Tom Owen, Ana M. V. Guedes, Elsa Abranches, Benjamin Kumpfmueller, Ruth V. Spriggs, Domingos Henrique, Melanie J. Welham
Publié dans: PLoS ONE, Numéro 8/4, 2013, Page(s) e60148, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0060148

Novel TAL1 targets beyond protein-coding genes: identification of TAL1-regulated microRNAs in T-cell acute lymphoblastic leukemia

Auteurs: N C Correia, K Durinck, A P Leite, M Ongenaert, P Rondou, F Speleman, F J Enguita, J T Barata
Publié dans: Leukemia, Numéro 27/7, 2013, Page(s) 1603-1606, ISSN 0887-6924
Éditeur: Nature Publishing Group
DOI: 10.1038/leu.2013.63

N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy

Auteurs: S. Falcone, W. Roman, K. Hnia, V. Gache, N. Didier, J. Laine, F. Aurade, I. Marty, I. Nishino, N. Charlet-Berguerand, N. B. Romero, G. Marazzi, D. Sassoon, J. Laporte, E. R. Gomes
Publié dans: EMBO Molecular Medicine, Numéro 6/11, 2014, Page(s) 1455-1475, ISSN 1757-4676
Éditeur: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201404436

RANKL/RANK/MMP-1 Molecular Triad Contributes to the Metastatic Phenotype of Breast and Prostate Cancer Cells In Vitro

Auteurs: Sandra Casimiro, Khalid S. Mohammad, Ricardo Pires, Joana Tato-Costa, Irina Alho, Rui Teixeira, António Carvalho, Sofia Ribeiro, Allan Lipton, Theresa A. Guise, Luis Costa
Publié dans: PLoS ONE, Numéro 8/5, 2013, Page(s) e63153, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0063153

Lymphotoxin-β receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype

Auteurs: Mónica T. Fernandes, Marinella N. Ghezzo, André B. Silveira, Ravi K. Kalathur, Vanda Póvoa, Ana R. Ribeiro, Sílvia R. Brandalise, Emmanuel Dejardin, Nuno L. Alves, Jacques Ghysdael, João T. Barata, José Andres Yunes, Nuno R. dos Santos
Publié dans: British Journal of Haematology, Numéro 171/5, 2015, Page(s) 736-751, ISSN 0007-1048
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/bjh.13760

In Vitro and In Vivo Analysis of RTK Inhibitor Efficacy and Identification of Its Novel Targets in Glioblastomas

Auteurs: Olga Martinho, Renato Silva-Oliveira, Vera Miranda-Gonçalves, Carlos Clara, José Reynaldo Almeida, André Lopes Carvalho, João Taborda Barata, Rui Manuel Reis
Publié dans: Translational Oncology, Numéro 6/2, 2013, Page(s) 187-IN20, ISSN 1936-5233
Éditeur: Neoplasia Press
DOI: 10.1593/tlo.12400

Plasma level of LDL-cholesterol at diagnosis is a predictor factor of breast tumor progression

Auteurs: Catarina Rodrigues dos Santos, Isabel Fonseca, Sérgio Dias, JC Mendes de Almeida
Publié dans: BMC Cancer, Numéro 14/1, 2014, Page(s) 132, ISSN 1471-2407
Éditeur: BioMed Central
DOI: 10.1186/1471-2407-14-132

IL-7R : Mr Hyde's twists and turns

Auteurs: J. T. Barata
Publié dans: Blood, Numéro 122/26, 2013, Page(s) 4151-4152, ISSN 0006-4971
Éditeur: American Society of Hematology
DOI: 10.1182/blood-2013-11-536987

Adult B-cell acute lymphoblastic leukemia cells display decreased PTEN activity and constitutive hyperactivation of PI3K/Akt pathway despite high PTEN protein levels

Auteurs: A. M. Gomes, M. V. D. Soares, P. Ribeiro, J. Caldas, V. Povoa, L. R. Martins, A. Melao, A. Serra-Caetano, A. B. de Sousa, J. F. Lacerda, J. T. Barata
Publié dans: Haematologica, Numéro 99/6, 2014, Page(s) 1062-1068, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2013.096438

MTA1 Promotes STAT3 Transcription and Pulmonary Metastasis in Breast Cancer

Auteurs: S. B. Pakala, S. K. Rayala, R.-A. Wang, K. Ohshiro, P. Mudvari, S. D. N. Reddy, Y. Zheng, R. Pires, S. Casimiro, M. R. Pillai, L. Costa, R. Kumar
Publié dans: Cancer Research, Numéro 73/12, 2013, Page(s) 3761-3770, ISSN 0008-5472
Éditeur: American Association for Cancer Research
DOI: 10.1158/0008-5472.CAN-12-3998

N-Cadherin Locks Left-Right Asymmetry by Ending the Leftward Movement of Hensen’s Node Cells

Auteurs: Raquel V. Mendes, Gabriel G. Martins, Ana M. Cristovão, Leonor Saúde
Publié dans: Developmental Cell, Numéro 30/3, 2014, Page(s) 353-360, ISSN 1534-5807
Éditeur: Cell Press
DOI: 10.1016/j.devcel.2014.06.010

Therapy-Induced Cellular Senescence Induces Epithelial-to-Mesenchymal Transition and Increases Invasiveness in Rectal Cancer

Auteurs: Joana Tato-Costa, Sandra Casimiro, Teresa Pacheco, Ricardo Pires, Afonso Fernandes, Irina Alho, Pedro Pereira, Paulo Costa, Henrique Bicha Castelo, João Ferreira, Luís Costa
Publié dans: Clinical Colorectal Cancer, 2015, ISSN 1533-0028
Éditeur: Cancer Information Group
DOI: 10.1016/j.clcc.2015.09.003

The role of low-molecular-weight protein tyrosine phosphatase (LMW-PTP ACP1) in oncogenesis

Auteurs: Irina Alho, Luís Costa, Manuel Bicho, Constança Coelho
Publié dans: Tumor Biology, Numéro 34/4, 2013, Page(s) 1979-1989, ISSN 1010-4283
Éditeur: Springer Verlag
DOI: 10.1007/s13277-013-0784-1

Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton

Auteurs: Manuela D’Alessandro, Karim Hnia, Vincent Gache, Catherine Koch, Christos Gavriilidis, David Rodriguez, Anne-Sophie Nicot, Norma B. Romero, Yannick Schwab, Edgar Gomes, Michel Labouesse, Jocelyn Laporte
Publié dans: Developmental Cell, Numéro 35/2, 2015, Page(s) 186-198, ISSN 1534-5807
Éditeur: Cell Press
DOI: 10.1016/j.devcel.2015.09.018

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia

Auteurs: André Bortolini Silveira, Angelo Brunelli Albertoni Laranjeira, Gisele Olinto Libanio Rodrigues, Rodrigues Leal, Bruno António Cardoso, João Taborda Barata, Rosendo Augusto Yunes, Nilson Ivo Tonin Zanchin, Sílvia Regina Brandalise, José Andrés Yunes
Publié dans: Oncotarget, Numéro 6/15, 2015, Page(s) 13105-13118, ISSN 1949-2553
Éditeur: Impact Journals
DOI: 10.18632/oncotarget.3524

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

Auteurs: Katie Bentley, Claudio Areias Franco, Andrew Philippides, Raquel Blanco, Martina Dierkes, Véronique Gebala, Fabio Stanchi, Martin Jones, Irene M. Aspalter, Guiseppe Cagna, Simone Weström, Lena Claesson-Welsh, Dietmar Vestweber, Holger Gerhardt
Publié dans: Nature Cell Biology, Numéro 16/4, 2014, Page(s) 309-321, ISSN 1465-7392
Éditeur: Nature Publishing Group
DOI: 10.1038/ncb2926

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo

Auteurs: Kristina Preuße, Lena Tveriakhina, Karin Schuster-Gossler, Cláudia Gaspar, Alexandra Isabel Rosa, Domingos Henrique, Achim Gossler, Michael Stauber
Publié dans: PLOS Genetics, Numéro 11/6, 2015, Page(s) e1005328, ISSN 1553-7404
Éditeur: PLOS
DOI: 10.1371/journal.pgen.1005328

Computational fluid dynamics assisted characterization of parafoveal hemodynamics in normal and diabetic eyes using adaptive optics scanning laser ophthalmoscopy

Auteurs: Yang Lu, Miguel O. Bernabeu, Jan Lammer, Charles C. Cai, Martin L. Jones, Claudio A. Franco, Lloyd Paul Aiello, Jennifer K. Sun
Publié dans: Biomedical Optics Express, Numéro 7/12, 2016, Page(s) 4958, ISSN 2156-7085
Éditeur: The Optical Society
DOI: 10.1364/BOE.7.004958

A system for studying mechanisms of neuromuscular junction development and maintenance

Auteurs: Valérie Vilmont, Bruno Cadot, Gilles Ouanounou, Edgar R. Gomes
Publié dans: Development, Numéro 143/13, 2016, Page(s) 2464-2477, ISSN 0950-1991
Éditeur: The Company of Biologists Ltd.
DOI: 10.1242/dev.130278

The impact of chronic intermittent hypoxia on hematopoiesis and the bone marrow microenvironment

Auteurs: Inês Alvarez-Martins, Leonor Remédio, Inês Matias, Lucília N. Diogo, Emília C. Monteiro, Sérgio Dias
Publié dans: Pflügers Archiv - European Journal of Physiology, Numéro 468/5, 2016, Page(s) 919-932, ISSN 0031-6768
Éditeur: Springer Verlag
DOI: 10.1007/s00424-016-1797-6

Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Auteurs: Susana L. Silva, Adriana S. Albuquerque, Ana Serra-Caetano, Russell B. Foxall, Ana R. Pires, Paula Matoso, Susana M. Fernandes, João Ferreira, Rémi Cheynier, Rui M. M. Victorino, Iris Caramalho, João T. Barata, Ana E. Sousa
Publié dans: Oncotarget, Numéro 7/11, 2016, Page(s) 12163-12175, ISSN 1949-2553
Éditeur: Impact Journals
DOI: 10.18632/oncotarget.7512

FOXO1 couples metabolic activity and growth state in the vascular endothelium

Auteurs: Kerstin Wilhelm, Katharina Happel, Guy Eelen, Sandra Schoors, Mark F. Oellerich, Radiance Lim, Barbara Zimmermann, Irene M. Aspalter, Claudio A. Franco, Thomas Boettger, Thomas Braun, Marcus Fruttiger, Klaus Rajewsky, Charles Keller, Jens C. Brüning, Holger Gerhardt, Peter Carmeliet, Michael Potente
Publié dans: Nature, Numéro 529/7585, 2016, Page(s) 216-220, ISSN 0028-0836
Éditeur: Nature Publishing Group
DOI: 10.1038/nature16498

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

Auteurs: Ivan Quétier, Jacqueline J.T. Marshall, Bradley Spencer-Dene, Sylvie Lachmann, Adele Casamassima, Claudio Franco, Sarah Escuin, Joseph T. Worrall, Priththivika Baskaran, Vinothini Rajeeve, Michael Howell, Andrew J. Copp, Gordon Stamp, Ian Rosewell, Pedro Cutillas, Holger Gerhardt, Peter J. Parker, Angus J.M. Cameron
Publié dans: Cell Reports, Numéro 14/3, 2016, Page(s) 440-448, ISSN 2211-1247
Éditeur: Cell Press
DOI: 10.1016/j.celrep.2015.12.049

Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity

Auteurs: Alice Melão, Maureen Spit, Bruno A. Cardoso, João T. Barata
Publié dans: Haematologica, Numéro 101/11, 2016, Page(s) 1368-1379, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2015.141143

LDL-Cholesterol Increases the Transcytosis of Molecules through Endothelial Monolayers

Auteurs: Ana Magalhaes, Inês Matias, Inês Palmela, Maria Alexandra Brito, Sérgio Dias
Publié dans: PLOS ONE, Numéro 11/10, 2016, Page(s) e0163988, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0163988

microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemia

Auteurs: Nádia C. Correia, Alice Melão, Vanda Póvoa, Leonor Sarmento, Marta Gómez de Cedrón, Marcos Malumbres, Francisco J. Enguita, João T. Barata
Publié dans: Oncotarget, Numéro 7/7, 2016, Page(s) 8268-8281, ISSN 1949-2553
Éditeur: Impact Journals
DOI: 10.18632/oncotarget.6987

Blood flow boosts BMP signaling to keep vessels in shape

Auteurs: Claudio A. Franco, Holger Gerhardt
Publié dans: The Journal of Cell Biology, Numéro 214/7, 2016, Page(s) 793-795, ISSN 0021-9525
Éditeur: Rockefeller University Press
DOI: 10.1083/jcb.201609038

Endothelial cell dynamics in vascular remodelling

Auteurs: Pedro Barbacena, Joana R. Carvalho, Claudio A. Franco
Publié dans: Clinical Hemorheology and Microcirculation, Numéro 64/4, 2017, Page(s) 557-563, ISSN 1386-0291
Éditeur: IOS Press
DOI: 10.3233/CH-168006

Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice

Auteurs: Sandra Trindade, Filipa Rijo-Ferreira, Tânia Carvalho, Daniel Pinto-Neves, Fabien Guegan, Francisco Aresta-Branco, Fabio Bento, Simon A. Young, Andreia Pinto, Jan Van Den Abbeele, Ruy M. Ribeiro, Sérgio Dias, Terry K. Smith, Luisa M. Figueiredo
Publié dans: Cell Host & Microbe, Numéro 19/6, 2016, Page(s) 837-848, ISSN 1931-3128
Éditeur: Cell Press
DOI: 10.1016/j.chom.2016.05.002

Dynein disruption perturbs post-synaptic components and contributes to impaired MuSK clustering at the NMJ: implication in ALS

Auteurs: Valérie Vilmont, Bruno Cadot, Elsa Vezin, Fabien Le Grand, Edgar R. Gomes
Publié dans: Scientific Reports, Numéro 6/1, 2016, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/srep27804

Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine Model

Auteurs: Ana C. Gregório, Nuno A. Fonseca, Vera Moura, Manuela Lacerda, Paulo Figueiredo, Sérgio Simões, Sérgio Dias, João Nuno Moreira
Publié dans: PLOS ONE, Numéro 11/11, 2016, Page(s) e0165817, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0165817

Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling

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Molecular Mechanisms of Bone Metastasis: Which Targets Came from the Bench to the Bedside?

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Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells

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Myofibril contraction and crosslinking drive nuclear movement to the periphery of skeletal muscle

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Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia

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From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia

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IL-7-Induced Proliferation of Human Naive CD4 T-Cells Relies on Continued Thymic Activity

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Morph or Move? How Distinct Endothelial Cell Responses to Blood Flow Shape Vascular Networks

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Radionuclides in oncology clinical practice – review of the literature

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Bone metastasis risk factors in breast cancer

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Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxj1a in zebrafish left-right organizer

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Improving quality of life in patients with advanced cancer: Targeting metastatic bone pain

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Gold Nanobeacons for Tracking Gene Silencing in Zebrafish

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Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium( ii ) catalyst

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A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases

Auteurs: Jean B. Bertoldo, Tiago Rodrigues, Lavinia Dunsmore, Francesco A. Aprile, Marta C. Marques, Leonardo A. Rosado, Omar Boutureira, Thomas B. Steinbrecher, Woody Sherman, Francisco Corzana, Hernán Terenzi, Gonçalo J.L. Bernardes
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Oxidative Activation of C–S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl over Phenyl Thioglycosides

Auteurs: Annabel Kitowski, Ester Jiménez-Moreno, Míriam Salvadó, Jordi Mestre, Sergio Castillón, Gonzalo Jiménez-Osés, Omar Boutureira, Gonçalo J. L. Bernardes
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Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo

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Short (16-mer) locked nucleic acid splice-switching oligonucleotides restore dystrophin production in Duchenne Muscular Dystrophy myotubes

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Transcription Dynamics Prevent RNA-Mediated Genomic Instability through SRPK2-Dependent DDX23 Phosphorylation

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Trends in therapeutic drug conjugates for bacterial diseases: a patent review

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Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs

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Site-Selective Modification of Proteins with Oxetanes

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Nickel-Catalyzed Azide–Alkyne Cycloaddition To Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water

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Deep intronic mutations and human disease

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Whole gene sequencing identifies deep-intronic variants with potential functional impact in patients with hypertrophic cardiomyopathy

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Laying Waste to Mercury: Inexpensive Sorbents Made from Sulfur and Recycled Cooking Oils

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Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

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A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages

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Pharmacological inhibition of the spliceosome subunit SF3b triggers exon junction complex-independent nonsense-mediated decay

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Inverse electron demand Diels–Alder reactions in chemical biology

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Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells

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Association of Anger Expression-Out with NK Cell Counts in Colorectal Cancer Patients

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Microtubule motors involved in nuclear movement during skeletal muscle differentiation

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Impact on sexual function of surgical treatment in rectal cancer

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Local Arrangement of Fibronectin by Myofibroblasts Governs Peripheral Nuclear Positioning in Muscle Cells

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Serum YB-1 (Y-box binding protein 1) as a biomarker of bone disease progression in patients with breast cancer and bone metastases

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YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

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LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration

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Nuclear positioning in skeletal muscle

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Casein kinase 2 controls the survival of normal thymic and leukemic γδ T cells via promotion of AKT signaling

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Dealing with the nucleus during cell migration

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Damage and protection cost curves for coastal floods within the 600 largest European cities

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PolNet: A Tool to Quantify Network-Level Cell Polarity and Blood Flow in Vascular Remodeling

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Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

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The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

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Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression

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SRF selectively controls tip cell invasive behavior in angiogenesis

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Generation and Characterization of a Novel Mouse Embryonic Stem Cell Line with a Dynamic Reporter of Nanog Expression

Auteurs: Elsa Abranches, Evguenia Bekman, Domingos Henrique
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Glycogen Synthase Kinase-3 Inhibition Enhances Translation of Pluripotency-Associated Transcription Factors to Contribute to Maintenance of Mouse Embryonic Stem Cell Self-Renewal

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Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency

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Generation of sensory hair cells by genetic programming with a combination of transcription factors

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Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo

Auteurs: Kristina Preuße, Lena Tveriakhina, Karin Schuster-Gossler, Cláudia Gaspar, Alexandra Isabel Rosa, Domingos Henrique, Achim Gossler, Michael Stauber
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Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells

Auteurs: Tiago G. Fernandes, Sofia T. Duarte, Mehrnaz Ghazvini, Cláudia Gaspar, Diana C. Santos, Ana R. Porteira, Gonçalo M. C. Rodrigues, Simone Haupt, Diogo M. Rombo, Judith Armstrong, Ana M. Sebastião, Joost Gribnau, Àngels Garcia-Cazorla, Oliver Brüstle, Domingos Henrique, Joaquim M. S. Cabral, Maria Margarida Diogo
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Heterogeneous lineage marker expression in naive embryonic stem cells is mostly due to spontaneous differentiation

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Transcriptome profiling of induced hair cells (iHCs) generated by combined expression of Gfi1, Pou4f3 and Atoh1 during embryonic stem cell differentiation

Auteurs: Aida Costa, Domingos Henrique
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Neuromesodermal progenitors and the making of the spinal cord

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Therapy-Induced Cellular Senescence Induces Epithelial-to-Mesenchymal Transition and Increases Invasiveness in Rectal Cancer

Auteurs: Joana Tato-Costa, Sandra Casimiro, Teresa Pacheco, Ricardo Pires, Afonso Fernandes, Irina Alho, Pedro Pereira, Paulo Costa, Henrique Bicha Castelo, João Ferreira, Luís Costa
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Targeting bone metastases in prostate cancer: improving clinical outcome

Auteurs: Jean-Jacques Body, Sandra Casimiro, Luís Costa
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Bone remodeling markers and bone metastases: From cancer research to clinical implications

Auteurs: Arlindo Ferreira, Irina Alho, Sandra Casimiro, Luís Costa
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Metadherin expression and lung relapse in patients with colorectal carcinoma

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RANKL enhances the effect of an antagonist of inhibitor of apoptosis proteins (cIAPs) in RANK-positive breast cancer cells

Auteurs: S. Casimiro, I. Alho, M. Bettencourt, R. Pires, A. Lipton, L. Costa
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Novel Insights into Breast Cancer Genetic Variance through RNA Sequencing

Auteurs: Anelia Horvath, Suresh Babu Pakala, Prakriti Mudvari, Sirigiri Divijendra Natha Reddy, Kazufumi Ohshiro, Sandra Casimiro, Ricardo Pires, Suzanne A. W. Fuqua, Masakazu Toi, Luis Costa, Sujit S. Nair, Saraswati Sukumar, Rakesh Kumar
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RANKL/RANK/MMP-1 Molecular Triad Contributes to the Metastatic Phenotype of Breast and Prostate Cancer Cells In Vitro

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MTA1 Promotes STAT3 Transcription and Pulmonary Metastasis in Breast Cancer

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The role of low-molecular-weight protein tyrosine phosphatase (LMW-PTP ACP1) in oncogenesis

Auteurs: Irina Alho, Luís Costa, Manuel Bicho, Constança Coelho
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Treatment of Cancer Pain by Targeting Cytokines

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Low Molecular Weight Protein Tyrosine Phosphatase Isoforms Regulate Breast Cancer Cells Migration through a RhoA Dependent Mechanism

Auteurs: Irina Alho, Luis Costa, Manuel Bicho, Constança Coelho
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The Bone Marrow-Mediated Protection of Myeloproliferative Neoplastic Cells to Vorinostat and Ruxolitinib Relies on the Activation of JNK and PI3K Signalling Pathways

Auteurs: Bruno A. Cardoso, Hélio Belo, João T. Barata, António M. Almeida
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CHK1 and replicative stress in T-cell leukemia: Can an irreverent tumor suppressor end up playing the oncogene?

Auteurs: Leonor M. Sarmento, João T. Barata
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PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia

Auteurs: André Bortolini Silveira, Angelo Brunelli Albertoni Laranjeira, Gisele Olinto Libanio Rodrigues, Rodrigues Leal, Bruno António Cardoso, João Taborda Barata, Rosendo Augusto Yunes, Nilson Ivo Tonin Zanchin, Sílvia Regina Brandalise, José Andrés Yunes
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Lymphotoxin-β receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype

Auteurs: Mónica T. Fernandes, Marinella N. Ghezzo, André B. Silveira, Ravi K. Kalathur, Vanda Póvoa, Ana R. Ribeiro, Sílvia R. Brandalise, Emmanuel Dejardin, Nuno L. Alves, Jacques Ghysdael, João T. Barata, José Andres Yunes, Nuno R. dos Santos
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Kinases, tails and more: Regulation of PTEN function by phosphorylation

Auteurs: Rita Fragoso, João T. Barata
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CHK1 overexpression in T-cell acute lymphoblastic leukemia is essential for proliferation and survival by preventing excessive replication stress

Auteurs: L M Sarmento, V Póvoa, R Nascimento, G Real, I Antunes, L R Martins, C Moita, P M Alves, M Abecasis, L F Moita, R M E Parkhouse, J P P Meijerink, J T Barata
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Apoptotic human neutrophil peptide-1 anti-tumor activity revealed by cellular biomechanics

Auteurs: Diana Gaspar, João M. Freire, Teresa R. Pacheco, João T. Barata, Miguel A.R.B. Castanho
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A Unified Nomenclature and Amino Acid Numbering for Human PTEN

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PTEN and leukemia stem cells

Auteurs: Rita Fragoso, João T. Barata
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PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events

Auteurs: R. D. Mendes, L. M. Sarmento, K. Cante-Barrett, L. Zuurbier, J. G. C. A. M. Buijs-Gladdines, V. Povoa, W. K. Smits, M. Abecasis, J. A. Yunes, E. Sonneveld, M. A. Horstmann, R. Pieters, J. T. Barata, J. P. P. Meijerink
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Adult B-cell acute lymphoblastic leukemia cells display decreased PTEN activity and constitutive hyperactivation of PI3K/Akt pathway despite high PTEN protein levels

Auteurs: A. M. Gomes, M. V. D. Soares, P. Ribeiro, J. Caldas, V. Povoa, L. R. Martins, A. Melao, A. Serra-Caetano, A. B. de Sousa, J. F. Lacerda, J. T. Barata
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Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor

Auteurs: Leila R. Martins, Yasser Perera, Paulo Lúcio, Maria G. Silva, Silvio E. Perea, João T. Barata
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Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia

Auteurs: A Lonetti, I L Antunes, F Chiarini, E Orsini, F Buontempo, F Ricci, P L Tazzari, P Pagliaro, F Melchionda, A Pession, A Bertaina, F Locatelli, J A McCubrey, J T Barata, A M Martelli
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IL-7R : Mr Hyde's twists and turns

Auteurs: J. T. Barata
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Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia

Auteurs: L R Martins, P Lúcio, A Melão, I Antunes, B A Cardoso, R Stansfield, M T S Bertilaccio, P Ghia, D Drygin, M G Silva, J T Barata
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Novel TAL1 targets beyond protein-coding genes: identification of TAL1-regulated microRNAs in T-cell acute lymphoblastic leukemia

Auteurs: N C Correia, K Durinck, A P Leite, M Ongenaert, P Rondou, F Speleman, F J Enguita, J T Barata
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Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling

Auteurs: F Buontempo, E Orsini, L R Martins, I Antunes, A Lonetti, F Chiarini, G Tabellini, C Evangelisti, C Evangelisti, F Melchionda, A Pession, A Bertaina, F Locatelli, J A McCubrey, A Cappellini, J T Barata, A M Martelli
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IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia

Auteurs: Daniel Ribeiro, Alice Melão, João T. Barata
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N-Cadherin Locks Left-Right Asymmetry by Ending the Leftward Movement of Hensen’s Node Cells

Auteurs: Raquel V. Mendes, Gabriel G. Martins, Ana M. Cristovão, Leonor Saúde
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Notch Signalling Is Required for the Formation of Structurally Stable Muscle Fibres in Zebrafish

Auteurs: Susana Pascoal, Joana Esteves de Lima, Jonathan D. Leslie, Simon M. Hughes, Leonor Saúde
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miR-363-5p regulates endothelial cell properties and their communication with hematopoietic precursor cells

Auteurs: Ana Costa, Joana Afonso, Catarina Osório, Ana L Gomes, Francisco Caiado, Joana Valente, Sandra I Aguiar, Francisco Pinto, Mário Ramirez, Sérgio Dias
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Bone Marrow-Derived CD11b+Jagged2+ Cells Promote Epithelial-to-Mesenchymal Transition and Metastasization in Colorectal Cancer

Auteurs: F. Caiado, T. Carvalho, I. Rosa, L. Remedio, A. Costa, J. Matos, B. Heissig, H. Yagita, K. Hattori, J. P. da Silva, P. Fidalgo, A. D. Pereira, S. Dias
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Plasma level of LDL-cholesterol at diagnosis is a predictor factor of breast tumor progression

Auteurs: Catarina Rodrigues dos Santos, Isabel Fonseca, Sérgio Dias, JC Mendes de Almeida
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LDL-cholesterol signaling induces breast cancer proliferation and invasion

Auteurs: Catarina Rodrigues dos Santos, Germana Domingues, Inês Matias, João Matos, Isabel Fonseca, José de Almeida, Sérgio Dias
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In Vitro and In Vivo Analysis of RTK Inhibitor Efficacy and Identification of Its Novel Targets in Glioblastomas

Auteurs: Olga Martinho, Renato Silva-Oliveira, Vera Miranda-Gonçalves, Carlos Clara, José Reynaldo Almeida, André Lopes Carvalho, João Taborda Barata, Rui Manuel Reis
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IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia

Auteurs: Daniel Ribeiro, Alice Melão, João T. Barata
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Apoptotic human neutrophil peptide-1 anti-tumor activity revealed by cellular biomechanics

Auteurs: Diana Gaspar, João M. Freire, Teresa R. Pacheco, João T. Barata, Miguel A.R.B. Castanho
Publié dans: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Numéro 1853/2, 2015, Page(s) 308-316, ISSN 0167-4889
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Transcriptome profiling of induced hair cells (iHCs) generated by combined expression of Gfi1, Pou4f3 and Atoh1 during embryonic stem cell differentiation

Auteurs: Aida Costa, Domingos Henrique
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Generation of sensory hair cells by genetic programming with a combination of transcription factors

Auteurs: A. Costa, L. Sanchez-Guardado, S. Juniat, J. E. Gale, N. Daudet, D. Henrique
Publié dans: Development, Numéro 142/11, 2015, Page(s) 1948-1959, ISSN 0950-1991
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The contemporary nucleus: A trip down memory lane

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Treatment of Cancer Pain by Targeting Cytokines

Auteurs: I. Vendrell, D. Macedo, I. Alho, M. R. Dionísio, L. Costa
Publié dans: Mediators of Inflammation, Numéro 2015, 2015, Page(s) 1-11, ISSN 0962-9351
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Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling

Auteurs: F Buontempo, E Orsini, L R Martins, I Antunes, A Lonetti, F Chiarini, G Tabellini, C Evangelisti, C Evangelisti, F Melchionda, A Pession, A Bertaina, F Locatelli, J A McCubrey, A Cappellini, J T Barata, A M Martelli
Publié dans: Leukemia, Numéro 28/3, 2013, Page(s) 543-553, ISSN 0887-6924
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RANKL enhances the effect of an antagonist of inhibitor of apoptosis proteins (cIAPs) in RANK-positive breast cancer cells

Auteurs: S. Casimiro, I. Alho, M. Bettencourt, R. Pires, A. Lipton, L. Costa
Publié dans: Journal of Bone Oncology, Numéro 2/3, 2013, Page(s) 116-122, ISSN 2212-1374
Éditeur: Elsevier GmbH
DOI: 10.1016/j.jbo.2013.07.001

The Bone Marrow-Mediated Protection of Myeloproliferative Neoplastic Cells to Vorinostat and Ruxolitinib Relies on the Activation of JNK and PI3K Signalling Pathways

Auteurs: Bruno A. Cardoso, Hélio Belo, João T. Barata, António M. Almeida
Publié dans: PLOS ONE, Numéro 10/12, 2015, Page(s) e0143897, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0143897

Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells

Auteurs: Tiago G. Fernandes, Sofia T. Duarte, Mehrnaz Ghazvini, Cláudia Gaspar, Diana C. Santos, Ana R. Porteira, Gonçalo M. C. Rodrigues, Simone Haupt, Diogo M. Rombo, Judith Armstrong, Ana M. Sebastião, Joost Gribnau, Àngels Garcia-Cazorla, Oliver Brüstle, Domingos Henrique, Joaquim M. S. Cabral, Maria Margarida Diogo
Publié dans: Biotechnology Journal, Numéro 10/10, 2015, Page(s) 1578-1588, ISSN 1860-6768
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/biot.201400751

Moving and positioning the nucleus in skeletal muscle – one step at a time

Auteurs: Bruno Cadot, Vincent Gache, Edgar R Gomes
Publié dans: Nucleus, Numéro 6/5, 2015, Page(s) 373-381, ISSN 1949-1034
Éditeur: Landes Bioscience
DOI: 10.1080/19491034.2015.1090073

Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia

Auteurs: L R Martins, P Lúcio, A Melão, I Antunes, B A Cardoso, R Stansfield, M T S Bertilaccio, P Ghia, D Drygin, M G Silva, J T Barata
Publié dans: Leukemia, Numéro 28/1, 2013, Page(s) 179-182, ISSN 0887-6924
Éditeur: Nature Publishing Group
DOI: 10.1038/leu.2013.232

Generation and Characterization of a Novel Mouse Embryonic Stem Cell Line with a Dynamic Reporter of Nanog Expression

Auteurs: Elsa Abranches, Evguenia Bekman, Domingos Henrique
Publié dans: PLoS ONE, Numéro 8/3, 2013, Page(s) e59928, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0059928

Bone Marrow-Derived CD11b+Jagged2+ Cells Promote Epithelial-to-Mesenchymal Transition and Metastasization in Colorectal Cancer

Auteurs: F. Caiado, T. Carvalho, I. Rosa, L. Remedio, A. Costa, J. Matos, B. Heissig, H. Yagita, K. Hattori, J. P. da Silva, P. Fidalgo, A. D. Pereira, S. Dias
Publié dans: Cancer Research, Numéro 73/14, 2013, Page(s) 4233-4246, ISSN 0008-5472
Éditeur: American Association for Cancer Research
DOI: 10.1158/0008-5472.CAN-13-0085

Metadherin expression and lung relapse in patients with colorectal carcinoma

Auteurs: Sandra Casimiro, Afonso Fernandes, António Gouveia Oliveira, Marco Franco, Ricardo Pires, Mafalda Peres, Margarida Matias, Joana Tato-Costa, Nuno Guerra, Madalena Ramos, Jorge Cruz, Luis Costa
Publié dans: Clinical & Experimental Metastasis, Numéro 31/6, 2014, Page(s) 689-696, ISSN 0262-0898
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10585-014-9659-0

Connecting the Nucleus to the Cytoskeleton for Nuclear Positioning and Cell Migration

Auteurs: Daniel S. Osorio, Edgar R. Gomes
Publié dans: Cancer Biology and the Nuclear Envelope, 2014, Page(s) 505-520, ISBN 978-1-4899-8032-8
Éditeur: Springer New York
DOI: 10.1007/978-1-4899-8032-8_23

Skeletal Muscle

Auteurs: B. Cadot, E.R. Gomes
Publié dans: Encyclopedia of Cell Biology, 2016, Page(s) 677-682, ISBN 9780123947963
Éditeur: Elsevier
DOI: 10.1016/B978-0-12-394447-4.20065-5

Imaging Pluripotency: Time-Lapse Analysis of Mouse Embryonic Stem Cells

Auteurs: Anna Pezzarossa, Ana M. V. Guedes, Domingos Henrique, Elsa Abranches
Publié dans: Embryonic Stem Cell Protocols, 2016, Page(s) 87-100, ISBN 978-1-4939-2954-2
Éditeur: Springer New York
DOI: 10.1007/7651_2015_255

Connecting the Nucleus to the Cytoskeleton for Nuclear Positioning and Cell Migration

Skeletal Muscle

Auteurs: B. Cadot, E.R. Gomes
Publié dans: Encyclopedia of Cell Biology, 2016, Page(s) 677-682, ISBN 9780123947963
Éditeur: Elsevier
DOI: 10.1016/B978-0-12-394447-4.20065-5

Imaging Pluripotency: Time-Lapse Analysis of Mouse Embryonic Stem Cells

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