Towards outstanding research and training in tumour biology at IMM

Rezultaty

High Resolution Microscopy Workshop
EC Performance Indicators Widening indicator application for the 3-year window time prior to ReTuBi

EC Performance Indicators Widening indicator application for the 3-year window time prior to ReTuBi

Second edition of the High-Resolution Microscopy Workshop

A second edition of the High-Resolution Microscopy Workshop will be organized on M34 due to the successful implementation of the first edition, the successful accomplishment of the objectives and the growing demand from the partnering institutions on participating in these type of practical activity.

Second edition of the Career development and soft skills for young scientists

A second edition of thethe Career development and soft skills for young scientists – From Lisbon to the World Workshop will be organized on M26 due to the successful implementation of the first edition, the successful accomplishment of the objectives and the growing demand from the partnering institutions on participating in these type of practical activity.

Career development and soft skills for young scientists
Brochure and flyer

ReTuBi website and logo

Publikacje

Computational fluid dynamics assisted characterization of parafoveal hemodynamics in normal and diabetic eyes using adaptive optics scanning laser ophthalmoscopy

Autorzy: Yang Lu, Miguel O. Bernabeu, Jan Lammer, Charles C. Cai, Martin L. Jones, Claudio A. Franco, Lloyd Paul Aiello, Jennifer K. Sun
Opublikowane w: Biomedical Optics Express, Numer 7/12, 2016, Strona(/y) 4958, ISSN 2156-7085
Wydawca: The Optical Society
DOI: 10.1364/BOE.7.004958

A system for studying mechanisms of neuromuscular junction development and maintenance

Autorzy: Valérie Vilmont, Bruno Cadot, Gilles Ouanounou, Edgar R. Gomes
Opublikowane w: Development, Numer 143/13, 2016, Strona(/y) 2464-2477, ISSN 0950-1991
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/dev.130278

The impact of chronic intermittent hypoxia on hematopoiesis and the bone marrow microenvironment

Autorzy: Inês Alvarez-Martins, Leonor Remédio, Inês Matias, Lucília N. Diogo, Emília C. Monteiro, Sérgio Dias
Opublikowane w: Pflügers Archiv - European Journal of Physiology, Numer 468/5, 2016, Strona(/y) 919-932, ISSN 0031-6768
Wydawca: Springer Verlag
DOI: 10.1007/s00424-016-1797-6

Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Autorzy: Susana L. Silva, Adriana S. Albuquerque, Ana Serra-Caetano, Russell B. Foxall, Ana R. Pires, Paula Matoso, Susana M. Fernandes, João Ferreira, Rémi Cheynier, Rui M. M. Victorino, Iris Caramalho, João T. Barata, Ana E. Sousa
Opublikowane w: Oncotarget, Numer 7/11, 2016, Strona(/y) 12163-12175, ISSN 1949-2553
Wydawca: Impact Journals
DOI: 10.18632/oncotarget.7512

FOXO1 couples metabolic activity and growth state in the vascular endothelium

Autorzy: Kerstin Wilhelm, Katharina Happel, Guy Eelen, Sandra Schoors, Mark F. Oellerich, Radiance Lim, Barbara Zimmermann, Irene M. Aspalter, Claudio A. Franco, Thomas Boettger, Thomas Braun, Marcus Fruttiger, Klaus Rajewsky, Charles Keller, Jens C. Brüning, Holger Gerhardt, Peter Carmeliet, Michael Potente
Opublikowane w: Nature, Numer 529/7585, 2016, Strona(/y) 216-220, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/nature16498

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

Autorzy: Ivan Quétier, Jacqueline J.T. Marshall, Bradley Spencer-Dene, Sylvie Lachmann, Adele Casamassima, Claudio Franco, Sarah Escuin, Joseph T. Worrall, Priththivika Baskaran, Vinothini Rajeeve, Michael Howell, Andrew J. Copp, Gordon Stamp, Ian Rosewell, Pedro Cutillas, Holger Gerhardt, Peter J. Parker, Angus J.M. Cameron
Opublikowane w: Cell Reports, Numer 14/3, 2016, Strona(/y) 440-448, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2015.12.049

Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity

Autorzy: Alice Melão, Maureen Spit, Bruno A. Cardoso, João T. Barata
Opublikowane w: Haematologica, Numer 101/11, 2016, Strona(/y) 1368-1379, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2015.141143

LDL-Cholesterol Increases the Transcytosis of Molecules through Endothelial Monolayers

Autorzy: Ana Magalhaes, Inês Matias, Inês Palmela, Maria Alexandra Brito, Sérgio Dias
Opublikowane w: PLOS ONE, Numer 11/10, 2016, Strona(/y) e0163988, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0163988

microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemia

Autorzy: Nádia C. Correia, Alice Melão, Vanda Póvoa, Leonor Sarmento, Marta Gómez de Cedrón, Marcos Malumbres, Francisco J. Enguita, João T. Barata
Opublikowane w: Oncotarget, Numer 7/7, 2016, Strona(/y) 8268-8281, ISSN 1949-2553
Wydawca: Impact Journals
DOI: 10.18632/oncotarget.6987

Blood flow boosts BMP signaling to keep vessels in shape

Autorzy: Claudio A. Franco, Holger Gerhardt
Opublikowane w: The Journal of Cell Biology, Numer 214/7, 2016, Strona(/y) 793-795, ISSN 0021-9525
Wydawca: Rockefeller University Press
DOI: 10.1083/jcb.201609038

Endothelial cell dynamics in vascular remodelling

Autorzy: Pedro Barbacena, Joana R. Carvalho, Claudio A. Franco
Opublikowane w: Clinical Hemorheology and Microcirculation, Numer 64/4, 2017, Strona(/y) 557-563, ISSN 1386-0291
Wydawca: IOS Press
DOI: 10.3233/CH-168006

Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice

Autorzy: Sandra Trindade, Filipa Rijo-Ferreira, Tânia Carvalho, Daniel Pinto-Neves, Fabien Guegan, Francisco Aresta-Branco, Fabio Bento, Simon A. Young, Andreia Pinto, Jan Van Den Abbeele, Ruy M. Ribeiro, Sérgio Dias, Terry K. Smith, Luisa M. Figueiredo
Opublikowane w: Cell Host & Microbe, Numer 19/6, 2016, Strona(/y) 837-848, ISSN 1931-3128
Wydawca: Cell Press
DOI: 10.1016/j.chom.2016.05.002

Dynein disruption perturbs post-synaptic components and contributes to impaired MuSK clustering at the NMJ: implication in ALS

Autorzy: Valérie Vilmont, Bruno Cadot, Elsa Vezin, Fabien Le Grand, Edgar R. Gomes
Opublikowane w: Scientific Reports, Numer 6/1, 2016, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep27804

Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine Model

Autorzy: Ana C. Gregório, Nuno A. Fonseca, Vera Moura, Manuela Lacerda, Paulo Figueiredo, Sérgio Simões, Sérgio Dias, João Nuno Moreira
Opublikowane w: PLOS ONE, Numer 11/11, 2016, Strona(/y) e0165817, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0165817

Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling

Autorzy: Claudio A Franco, Martin L Jones, Miguel O Bernabeu, Anne-Clemence Vion, Pedro Barbacena, Jieqing Fan, Thomas Mathivet, Catarina G Fonseca, Anan Ragab, Terry P Yamaguchi, Peter V Coveney, Richard A Lang, Holger Gerhardt
Opublikowane w: eLife, Numer 5, 2016, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/eLife.07727

MiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemia

Autorzy: Nádia C. Correia, Rita Fragoso, Tânia Carvalho, Francisco J. Enguita, João T. Barata
Opublikowane w: Scientific Reports, Numer 6/1, 2016, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep31894

Organização e implementação de uma consulta de cardio‐oncologia

Autorzy: Manuela Fiuza, Leonor Ribeiro, Andreia Magalhães, Ana Rita Sousa, Miguel Nobre Menezes, Marília Jorge, Luís Costa, Fausto José Pinto
Opublikowane w: Revista Portuguesa de Cardiologia, Numer 35/9, 2016, Strona(/y) 485-494, ISSN 0870-2551
Wydawca: Sociedade Portuguesa De Cardiologia
DOI: 10.1016/j.repc.2016.04.006

The prognostic role of RANK SNP rs34945627 in breast cancer patients with bone metastases

Autorzy: Arlindo Ferreira, Irina Alho, Inês Vendrell, Marta Melo, Raquel Brás, Ana Lúcia Costa, Ana Rita Sousa, André Mansinho, Catarina Abreu, Catarina Pulido, Daniela Macedo, Teresa Pacheco, Lurdes Correia, Luis Costa, Sandra Casimiro
Opublikowane w: Oncotarget, Numer 7/27, 2016, Strona(/y) 41380-41389, ISSN 1949-2553
Wydawca: Impact Journals
DOI: 10.18632/oncotarget.9356

N-Telopeptide of Type I Collagen Long-Term Dynamics in Breast Cancer Patients With Bone Metastases: Clinical Outcomes and Influence of Extraskeletal Metastases

Autorzy: A. R. Ferreira, I. Alho, N. Shan, M. Matias, M. Faria, S. Casimiro, K. Leitzel, S. Ali, A. Lipton, L. Costa
Opublikowane w: The Oncologist, Numer 21/12, 2016, Strona(/y) 1418-1426, ISSN 1083-7159
Wydawca: AlphaMed Press Inc
DOI: 10.1634/theoncologist.2015-0527

Radiolabeled block copolymer micelles for image-guided drug delivery

Autorzy: Elisabete Ribeiro, Irina Alho, Fernanda Marques, Lurdes Gano, Isabel Correia, João D.G. Correia, Sandra Casimiro, Luís Costa, Isabel Santos, Célia Fernandes
Opublikowane w: International Journal of Pharmaceutics, Numer 515/1-2, 2016, Strona(/y) 692-701, ISSN 0378-5173
Wydawca: Elsevier BV
DOI: 10.1016/j.ijpharm.2016.11.004

Dynamic modeling of bone metastasis, microenvironment and therapy

Autorzy: Rui Moura Coelho, João Miranda Lemos, Irina Alho, Duarte Valério, Arlindo R Ferreira, Luís Costa, Susana Vinga
Opublikowane w: Journal of Theoretical Biology, Numer 391, 2016, Strona(/y) 1-12, ISSN 0022-5193
Wydawca: Academic Press
DOI: 10.1016/j.jtbi.2015.11.024

Variation in type of adjuvant chemotherapy received among patients with stage I breast cancer: A multi-institutional Portuguese cohort study

Autorzy: Arlindo R. Ferreira, Ana Palha, Lurdes Correia, Pedro Filipe, Vasco Rodrigues, Luís Costa, Ana Miranda, Rosário André, João Fernandes, Joaquim Gouveia, José Luís Passos-Coelho, António Moreira, Margarida Brito, Joana Ribeiro, Otto Metzger-Filho, Nancy U. Lin, Inês Vaz-Luís
Opublikowane w: The Breast, Numer 29, 2016, Strona(/y) 68-73, ISSN 0960-9776
Wydawca: Churchill Livingstone
DOI: 10.1016/j.breast.2016.07.004

Molecular Mechanisms of Bone Metastasis: Which Targets Came from the Bench to the Bedside?

Autorzy: Sandra Casimiro, Arlindo Ferreira, André Mansinho, Irina Alho, Luis Costa
Opublikowane w: International Journal of Molecular Sciences, Numer 17/9, 2016, Strona(/y) 1415, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms17091415

Health resource utilization associated with skeletal-related events: results from a retrospective European study

Autorzy: Jean-Jacques Body, João Pereira, Harm Sleeboom, Nikos Maniadakis, Evangelos Terpos, Yves Pascal Acklin, Jindrich Finek, Oliver Gunther, Guy Hechmati, Tony Mossman, Luis Costa, Wojciech Rogowski, Hareth Nahi, Roger von Moos
Opublikowane w: The European Journal of Health Economics, Numer 17/6, 2016, Strona(/y) 711-721, ISSN 1618-7598
Wydawca: Springer Verlag
DOI: 10.1007/s10198-015-0716-7

Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells

Autorzy: Petra Gimpel, Yin Loon Lee, Radoslaw M. Sobota, Alessandra Calvi, Victoria Koullourou, Rutti Patel, Kamel Mamchaoui, François Nédélec, Sue Shackleton, Jan Schmoranzer, Brian Burke, Bruno Cadot, Edgar R. Gomes
Opublikowane w: Current Biology, Numer 27/19, 2017, Strona(/y) 2999-3009.e9, ISSN 0960-9822
Wydawca: Cell Press
DOI: 10.1016/j.cub.2017.08.031

Myofibril contraction and crosslinking drive nuclear movement to the periphery of skeletal muscle

Autorzy: William Roman, João P. Martins, Filomena A. Carvalho, Raphael Voituriez, Jasmine V. G. Abella, Nuno C. Santos, Bruno Cadot, Michael Way, Edgar R. Gomes
Opublikowane w: Nature Cell Biology, Numer 19/10, 2017, Strona(/y) 1189-1201, ISSN 1465-7392
Wydawca: Nature Publishing Group
DOI: 10.1038/ncb3605

<em>In Vitro</em> Differentiation of Mature Myofibers for Live Imaging

Autorzy: Mafalda R. Pimentel, Sestina Falcone, Bruno Cadot, Edgar R. Gomes
Opublikowane w: Journal of Visualized Experiments, Numer 119, 2017, ISSN 1940-087X
Wydawca: MYJoVE Corporation
DOI: 10.3791/55141

Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia

Autorzy: Cecilia Evangelisti, Alessandra Cappellini, Mariana Oliveira, Rita Fragoso, João T. Barata, Alice Bertaina, Franco Locatelli, Carolina Simioni, Luca M. Neri, Francesca Chiarini, Annalisa Lonetti, Francesca Buontempo, Ester Orsini, Andrea Pession, Lucia Manzoli, Alberto Maria Martelli, Camilla Evangelisti
Opublikowane w: Journal of Cellular Physiology, 2017, ISSN 0021-9541
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/jcp.26135

From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia

Autorzy: Mariana L. Oliveira, Padma Akkapeddi, Isabel Alcobia, Afonso R. Almeida, Bruno A. Cardoso, Rita Fragoso, Teresa L. Serafim, João T. Barata
Opublikowane w: Cellular Signalling, Numer 38, 2017, Strona(/y) 10-25, ISSN 0898-6568
Wydawca: Elsevier BV
DOI: 10.1016/j.cellsig.2017.06.011

IL-7-Induced Proliferation of Human Naive CD4 T-Cells Relies on Continued Thymic Activity

Autorzy: Susana L. Silva, Adriana S. Albuquerque, Paula Matoso, Bénédicte Charmeteau-de-Muylder, Rémi Cheynier, Dário Ligeiro, Miguel Abecasis, Rui Anjos, João T. Barata, Rui M. M. Victorino, Ana E. Sousa
Opublikowane w: Frontiers in Immunology, Numer 8, 2017, ISSN 1664-3224
Wydawca: Frontiers in Immunology
DOI: 10.3389/fimmu.2017.00020

Morph or Move? How Distinct Endothelial Cell Responses to Blood Flow Shape Vascular Networks

Autorzy: Claudio A. Franco, Holger Gerhardt
Opublikowane w: Developmental Cell, Numer 41/6, 2017, Strona(/y) 574-576, ISSN 1534-5807
Wydawca: Cell Press
DOI: 10.1016/j.devcel.2017.06.008

Radionuclides in oncology clinical practice – review of the literature

Autorzy: Helena Luna Pais, Irina Alho, Inês Vendrell, André Mansinho, Luís Costa
Opublikowane w: Dalton Transactions, Numer 46/42, 2017, Strona(/y) 14475-14487, ISSN 1477-9226
Wydawca: Royal Society of Chemistry
DOI: 10.1039/C7DT01929G

Bone metastasis risk factors in breast cancer

Autorzy: Catarina Pulido, Inês Vendrell, Arlindo R Ferreira, Sandra Casimiro, André Mansinho, Irina Alho, Luís Costa
Opublikowane w: ecancermedicalscience, Numer 11, 2017, ISSN 1754-6605
Wydawca: Ecancermedicalscience
DOI: 10.3332/ecancer.2017.715

Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxj1a in zebrafish left-right organizer

Autorzy: Barbara Tavares, Raquel Jacinto, Pedro Sampaio, Sara Pestana, Andreia Pinto, Andreia Vaz, Mónica Roxo-Rosa, Rui Gardner, Telma Lopes, Britta Schilling, Ian Henry, Leonor Saúde, Susana Santos Lopes
Opublikowane w: eLife, Numer 6, 2017, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/eLife.25165

Improving quality of life in patients with advanced cancer: Targeting metastatic bone pain

Autorzy: Roger von Moos, Luis Costa, Carla Ida Ripamonti, Daniela Niepel, Daniele Santini
Opublikowane w: European Journal of Cancer, Numer 71, 2017, Strona(/y) 80-94, ISSN 0959-8049
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.ejca.2016.10.021

Gold Nanobeacons for Tracking Gene Silencing in Zebrafish

Autorzy: Milton Cordeiro, Lara Carvalho, Joana Silva, Leonor Saúde, Alexandra Fernandes, Pedro Baptista
Opublikowane w: Nanomaterials, Numer 7/1, 2017, Strona(/y) 10, ISSN 2079-4991
Wydawca: Nanomaterials
DOI: 10.3390/nano7010010

Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium( ii ) catalyst

Autorzy: Terence T.-L. Kwan, Omar Boutureira, Elizabeth C. Frye, Stephen J. Walsh, Moni K. Gupta, Stephen Wallace, Yuteng Wu, Fengzhi Zhang, Hannah F. Sore, Warren R. J. D. Galloway, Jason W. Chin, Martin Welch, Gonçalo J. L. Bernardes, David R. Spring
Opublikowane w: Chem. Sci., Numer 8/5, 2017, Strona(/y) 3871-3878, ISSN 2041-6520
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c6sc05313k

A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases

Autorzy: Jean B. Bertoldo, Tiago Rodrigues, Lavinia Dunsmore, Francesco A. Aprile, Marta C. Marques, Leonardo A. Rosado, Omar Boutureira, Thomas B. Steinbrecher, Woody Sherman, Francisco Corzana, Hernán Terenzi, Gonçalo J.L. Bernardes
Opublikowane w: Chem, Numer 3/4, 2017, Strona(/y) 665-677, ISSN 2451-9294
Wydawca: Chem
DOI: 10.1016/j.chempr.2017.07.009

Oxidative Activation of C–S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl over Phenyl Thioglycosides

Autorzy: Annabel Kitowski, Ester Jiménez-Moreno, Míriam Salvadó, Jordi Mestre, Sergio Castillón, Gonzalo Jiménez-Osés, Omar Boutureira, Gonçalo J. L. Bernardes
Opublikowane w: Organic Letters, Numer 19/19, 2017, Strona(/y) 5490-5493, ISSN 1523-7060
Wydawca: American Chemical Society
DOI: 10.1021/acs.orglett.7b02886

Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo

Autorzy: Nuria Martínez-Sáez, Shuang Sun, Davide Oldrini, Pietro Sormanni, Omar Boutureira, Filippo Carboni, Ismael Compañón, Michael J. Deery, Michele Vendruscolo, Francisco Corzana, Roberto Adamo, Gonçalo J. L. Bernardes
Opublikowane w: Angewandte Chemie International Edition, Numer 56/47, 2017, Strona(/y) 14963-14967, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201708847

Short (16-mer) locked nucleic acid splice-switching oligonucleotides restore dystrophin production in Duchenne Muscular Dystrophy myotubes

Autorzy: Vanessa Borges Pires, Ricardo Simões, Kamel Mamchaoui, Célia Carvalho, Maria Carmo-Fonseca
Opublikowane w: PLOS ONE, Numer 12/7, 2017, Strona(/y) e0181065, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0181065

Transcription Dynamics Prevent RNA-Mediated Genomic Instability through SRPK2-Dependent DDX23 Phosphorylation

Autorzy: Sreerama Chaitanya Sridhara, Sílvia Carvalho, Ana Rita Grosso, Lina Marcela Gallego-Paez, Maria Carmo-Fonseca, Sérgio Fernandes de Almeida
Opublikowane w: Cell Reports, Numer 18/2, 2017, Strona(/y) 334-343, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2016.12.050

Trends in therapeutic drug conjugates for bacterial diseases: a patent review

Autorzy: Pedro M. S. D. Cal, Maria J. Matos, Gonçalo J. L. Bernardes
Opublikowane w: Expert Opinion on Therapeutic Patents, Numer 27/2, 2017, Strona(/y) 179-189, ISSN 1354-3776
Wydawca: Ashley Publications Ltd.
DOI: 10.1080/13543776.2017.1259411

Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs

Autorzy: Margarita Schlackow, Takayuki Nojima, Tomas Gomes, Ashish Dhir, Maria Carmo-Fonseca, Nick J. Proudfoot
Opublikowane w: Molecular Cell, Numer 65/1, 2017, Strona(/y) 25-38, ISSN 1097-2765
Wydawca: Cell Press
DOI: 10.1016/j.molcel.2016.11.029

Site-Selective Modification of Proteins with Oxetanes

Autorzy: Omar Boutureira, Nuria Martínez-Sáez, Kevin M. Brindle, André A. Neves, Francisco Corzana, Gonçalo J. L. Bernardes
Opublikowane w: Chemistry - A European Journal, Numer 23/27, 2017, Strona(/y) 6483-6489, ISSN 0947-6539
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201700745

Nickel-Catalyzed Azide–Alkyne Cycloaddition To Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water

Autorzy: Woo Gyum Kim, Mi Eun Kang, Jae Bin Lee, Min Ho Jeon, Sungmin Lee, Jungha Lee, Bongseo Choi, Pedro M. S. D. Cal, Sebyung Kang, Jung-Min Kee, Gonçalo J. L. Bernardes, Jan-Uwe Rohde, Wonyoung Choe, Sung You Hong
Opublikowane w: Journal of the American Chemical Society, Numer 139/35, 2017, Strona(/y) 12121-12124, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.7b06338

Deep intronic mutations and human disease

Autorzy: Rita Vaz-Drago, Noélia Custódio, Maria Carmo-Fonseca
Opublikowane w: Human Genetics, Numer 136/9, 2017, Strona(/y) 1093-1111, ISSN 0340-6717
Wydawca: Springer Verlag
DOI: 10.1007/s00439-017-1809-4

Whole gene sequencing identifies deep-intronic variants with potential functional impact in patients with hypertrophic cardiomyopathy

Autorzy: Rita Mendes de Almeida, Joana Tavares, Sandra Martins, Teresa Carvalho, Francisco J. Enguita, Dulce Brito, Maria Carmo-Fonseca, Luís Rocha Lopes
Opublikowane w: PLOS ONE, Numer 12/8, 2017, Strona(/y) e0182946, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0182946

Laying Waste to Mercury: Inexpensive Sorbents Made from Sulfur and Recycled Cooking Oils

Autorzy: Max J. H. Worthington, Renata L. Kucera, Inês S. Albuquerque, Christopher T. Gibson, Alexander Sibley, Ashley D. Slattery, Jonathan A. Campbell, Salah F. K. Alboaiji, Katherine A. Muller, Jason Young, Nick Adamson, Jason R. Gascooke, Deshetti Jampaiah, Ylias M. Sabri, Suresh K. Bhargava, Samuel J. Ippolito, David A. Lewis, Jamie S. Quinton, Amanda V. Ellis, Alexander Johs, Gonçalo J. L. Bernarde
Opublikowane w: Chemistry - A European Journal, Numer 23/64, 2017, Strona(/y) 16219-16230, ISSN 0947-6539
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201702871

Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

Autorzy: Ester Jiménez-Moreno, Zijian Guo, Bruno L. Oliveira, Inês S. Albuquerque, Annabel Kitowski, Ana Guerreiro, Omar Boutureira, Tiago Rodrigues, Gonzalo Jiménez-Osés, Gonçalo J. L. Bernardes
Opublikowane w: Angewandte Chemie International Edition, Numer 56/1, 2017, Strona(/y) 243-247, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201609607

A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages

Autorzy: Mafalda M. A. Pereira, Inês Mahú, Elsa Seixas, Noelia Martinéz-Sánchez, Nadiya Kubasova, Roksana M Pirzgalska, Paul Cohen, Marcelo O Dietrich, Miguel López, Gonçalo J. L. Bernardes, Ana I. Domingos
Opublikowane w: Nature Communications, Numer 8, 2017, Strona(/y) 14967, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms14967

Pharmacological inhibition of the spliceosome subunit SF3b triggers exon junction complex-independent nonsense-mediated decay

Autorzy: Teresa Carvalho, Sandra Martins, José Rino, Sérgio Marinho, Maria Carmo-Fonseca
Opublikowane w: Journal of Cell Science, Numer 130/9, 2017, Strona(/y) 1519-1531, ISSN 0021-9533
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/jcs.202200

Inverse electron demand Diels–Alder reactions in chemical biology

Autorzy: B. L. Oliveira, Z. Guo, G. J. L. Bernardes
Opublikowane w: Chem. Soc. Rev., Numer 46/16, 2017, Strona(/y) 4895-4950, ISSN 0306-0012
Wydawca: Royal Society of Chemistry
DOI: 10.1039/C7CS00184C

Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells

Autorzy: Pedro M. S. D. Cal, Florian Sieglitz, Fábio M. F. Santos, Cátia Parente Carvalho, Ana Guerreiro, Jean B. Bertoldo, Uwe Pischel, Pedro M. P. Gois, Gonçalo J. L. Bernardes
Opublikowane w: Chem. Commun., Numer 53/2, 2017, Strona(/y) 368-371, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
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Association of Anger Expression-Out with NK Cell Counts in Colorectal Cancer Patients

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Notch Signalling Is Required for the Formation of Structurally Stable Muscle Fibres in Zebrafish

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Skeletal Muscle

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