The transcription-related DNA damage response

Publicaciones

Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver

Autores: Marta Rodríguez-Martínez, Thierry Boissiére, Melvin Noe Gonzalez, Kevin Litchfield, Richard Mitter, Jane Walker, Svend Kjœr, Mohamed Ismail, Julian Downward, Charles Swanton, Jesper Q. Svejstrup
Publicado en: Cell, Edición 181/6, 2020, Página(s) 1395-1405.e11, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2020.04.014

The ASC-1 Complex Disassembles Collided Ribosomes

Autores: Szymon Juszkiewicz, Shaun H. Speldewinde, Li Wan, Jesper Q. Svejstrup, Ramanujan S. Hegde
Publicado en: Molecular Cell, Edición 79/4, 2020, Página(s) 603-614.e8, ISSN 1097-2765
Editor: Cell Press
DOI: 10.1016/j.molcel.2020.06.006

Translation stress and collided ribosomes are co-activators of cGAS

Autores: Li Wan; Szymon Juszkiewicz; Daniel Blears; Prashanth Kumar Bajpe; Zhong Han; Zhong Han; Peter Faull; Richard Mitter; Aengus Stewart; Ambrosius P. Snijders; Ramanujan S. Hegde; Jesper Q. Svejstrup; Jesper Q. Svejstrup
Publicado en: Molecular Cell, Edición 2, 2021, ISSN 1097-4164
Editor: Elsevier
DOI: 10.1016/j.molcel.2021.05.018

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Autores: Ana Tufegdžić Vidaković, Richard Mitter, Gavin P. Kelly, Michelle Neumann, Michelle Harreman, Marta Rodríguez-Martínez, Anna Herlihy, Juston C. Weems, Stefan Boeing, Vesela Encheva, Liam Gaul, Laura Milligan, David Tollervey, Ronald C. Conaway, Joan W. Conaway, Ambrosius P. Snijders, Aengus Stewart, Jesper Q. Svejstrup
Publicado en: Cell, Edición 180/6, 2020, Página(s) 1245-1261.e21, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2020.02.009

Multiplex Cell Fate Tracking by Flow Cytometry

Autores: Marta Rodríguez-Martínez, Stephanie A. Hills, John F. X. Diffley, Jesper Q. Svejstrup
Publicado en: Methods and Protocols, Edición 3/3, 2020, Página(s) 50, ISSN 2409-9279
Editor: MDPI
DOI: 10.3390/mps3030050

Transcription-coupled repair and the transcriptional response to UV-Irradiation.

Autores: Liam Gaul; Jesper Q. Svejstrup
Publicado en: DNA Repair, Edición 4, 2021, ISSN 1568-7864
Editor: Elsevier BV
DOI: 10.1016/j.dnarep.2021.103208

Annotation matters: validating the discovery of cancer drivers

Autores: Marta Rodríguez-Martínez, Jesper Q. Svejstrup
Publicado en: Molecular & Cellular Oncology, Edición 7/6, 2020, Página(s) 1806679, ISSN 2372-3556
Editor: Taylor and Francis
DOI: 10.1080/23723556.2020.1806679

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

Autores: Zheng Fan, Jennifer R. Devlin, Simon J. Hogg, Maria A. Doyle, Paul F. Harrison, Izabela Todorovski, Leonie A. Cluse, Deborah A. Knight, Jarrod J. Sandow, Gareth Gregory, Andrew Fox, Traude H. Beilharz, Nicholas Kwiatkowski, Nichollas E. Scott, Ana Tufegdzic Vidakovic, Gavin P. Kelly, Jesper Q. Svejstrup, Matthias Geyer, Nathanael S. Gray, Stephin J. Vervoort, Ricky W. Johnstone
Publicado en: Science Advances, Edición 6/18, 2020, Página(s) eaaz5041, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aaz5041

Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage

Autores: Juston C. Weems, Brian D. Slaughter, Jay R. Unruh, Stefan Boeing, Shawn M. Hall, Merry B. McLaird, Takashi Yasukawa, Teijiro Aso, Jesper Q. Svejstrup, Joan W. Conaway, Ronald C. Conaway
Publicado en: Journal of Biological Chemistry, Edición 292/16, 2017, Página(s) 6431-6437, ISSN 0021-9258
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.C117.777946

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene

Autores: Laura Williamson, Marco Saponaro, Stefan Boeing, Philip East, Richard Mitter, Theodoros Kantidakis, Gavin P. Kelly, Anna Lobley, Jane Walker, Bradley Spencer-Dene, Michael Howell, Aengus Stewart, Jesper Q. Svejstrup
Publicado en: Cell, Edición 168/5, 2017, Página(s) 843-855.e13, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2017.01.019

The Cellular Response to Transcription-Blocking DNA Damage

Autores: Lea H. Gregersen, Jesper Q. Svejstrup
Publicado en: Trends in Biochemical Sciences, Edición 43/5, 2018, Página(s) 327-341, ISSN 0968-0004
Editor: Elsevier BV
DOI: 10.1016/j.tibs.2018.02.010

A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin

Autores: Michael Lim, Joseph A. Newman, Hannah L. Williams, Laura Masino, Hazel Aitkenhead, Angeline E. Gravard, Opher Gileadi, Jesper Q. Svejstrup
Publicado en: Structure, Edición 27/8, 2019, Página(s) 1316-1325.e6, ISSN 2352-0124
Editor: Elsevier Limited

Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2AZ-containing nucleosomes

Autores: Aylin Cakiroglu, Cedric R. Clapier, Andreas H. Ehrensberger, Elodie Darbo, Bradley R. Cairns, Nicholas M. Luscombe, Jesper Q. Svejstrup
Publicado en: Genome Research, Edición 29/6, 2019, Página(s) 988-998, ISSN 1088-9051
Editor: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.243139.118

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins

Autores: Lea H. Gregersen, Richard Mitter, Alejandro P. Ugalde, Takayuki Nojima, Nicholas J. Proudfoot, Reuven Agami, Aengus Stewart, Jesper Q. Svejstrup
Publicado en: Cell, Edición 177/7, 2019, Página(s) 1797-1813.e18, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2019.04.038

Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability

Autores: Diana Zatreanu, Zhong Han, Richard Mitter, Emanuela Tumini, Hannah Williams, Lea Gregersen, A. Barbara Dirac-Svejstrup, Stefania Roma, Aengus Stewart, Andres Aguilera, Jesper Q. Svejstrup
Publicado en: Molecular Cell, Edición 76/1, 2019, Página(s) 57-69.e9, ISSN 1097-2765
Editor: Cell Press
DOI: 10.1016/j.molcel.2019.07.037

Analysis of RNA polymerase II ubiquitylation and proteasomal degradation

Autores: Ana Tufegdzic Vidakovic, Michelle Harreman, A. Barbara Dirac-Svejstrup, Stefan Boeing, Anindya Roy, Vesela Encheva, Michelle Neumann, Marcus Wilson, Ambrosius P. Snijders, Jesper Q. Svejstrup
Publicado en: Methods, Edición 159-160, 2019, Página(s) 146-156, ISSN 1046-2023
Editor: Academic Press
DOI: 10.1016/j.ymeth.2019.02.005

DDI2 Is a Ubiquitin-Directed Endoprotease Responsible for Cleavage of Transcription Factor NRF1

Autores: A. Barbara Dirac-Svejstrup, Jane Walker, Peter Faull, Vesela Encheva, Vyacheslav Akimov, Michele Puglia, David Perkins, Sandra Kümper, Suchete S. Hunjan, Blagoy Blagoev, Ambrosius P. Snijders, David J. Powell, Jesper Q. Svejstrup
Publicado en: Molecular Cell, Edición 79/2, 2020, Página(s) 332-341.e7, ISSN 1097-2765
Editor: Cell Press
DOI: 10.1016/j.molcel.2020.05.035

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