An integrated approach to understanding the impact of de novo mutations on the mammalian genome

Publications

De Novo Mutation Rate Variation and Its Determinants in Chlamydomonas

Auteurs: Eugenio López-Cortegano; Rory J. Craig; Jobran Chebib; Toby Samuels; Andrew D. Morgan; Susanne A. Kraemer; Katharina B. Böndel; Rob W. Ness; Nick Colegrave; Peter D. Keightley
Publié dans: López-Cortegano , E , Craig , R J , Chebib , J , Samuels , T , Morgan , A D , Kraemer , S A , Böndel , K B , Ness , R W , Colegrave , N , Keightley , P D & Hendrickson , H (ed.) 2021 , ' De novo mutation rate variation and its determinants in Chlamydomonas ' , Molecular Biology and Evolution , vol. 38 , no. 9 , msab140 , pp. 3709–3723 . https://doi.org/10.1093/molbev/msab140, Numéro 1, 2021, ISSN 1537-1719
Éditeur: OUP SMBE
DOI: 10.1093/molbev/msab140

Fitness decline under osmotic stress in Caenorhabditis elegans populations subjected to spontaneous mutation accumulation at varying population sizes.

Auteurs: Katju, V., Packard, L. B. and Keightley, P. D.
Publié dans: Evolution, 2018, ISSN 1558-5646
Éditeur: Wiley

Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii

Auteurs: Katharina B. Böndel, Susanne A. Kraemer, Toby Samuels, Deirdre McClean, Josianne Lachapelle, Rob W. Ness, Nick Colegrave, Peter D. Keightley
Publié dans: PLOS Biology, Numéro 17/6, 2019, Page(s) e3000192, ISSN 1545-7885
Éditeur: PLoS
DOI: 10.1371/journal.pbio.3000192

Comparative genomics of Chlamydomonas.

Auteurs: Craig, R. J., Hasan, A. R., Ness, R. W. and Keightley, P. D.
Publié dans: Plant Cell, 2021, ISSN 1040-4651
Éditeur: American Society of Plant Biologists

The distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii inferred using frequency changes under experimental evolution

Auteurs: Katharina B. Böndel; Toby Samuels; Rory J. Craig; Rob W. Ness; Nick Colegrave; Peter D. Keightley
Publié dans: PLoS Genetics, Numéro 3, 2022, ISSN 1553-7404
Éditeur: Public Library of Science
DOI: 10.1371/journal.pgen.1009840

Rates and spectra of de novo structural mutations in<i>Chlamydomonas reinhardtii</i>

Auteurs: Eugenio López-Cortegano; Rory J. Craig; Jobran Chebib; Eniolaye J. Balogun; Peter D. Keightley
Publié dans: Genome Research, Numéro 2, 2021, ISSN 1549-5469
Éditeur: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.276957.122

Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site.

Auteurs: Chebib, J., Jackson, B. C., López-Cortegano, E., Tautz, D. and Keightley, P. D.
Publié dans: Heredity, 2020, ISSN 1365-2540
Éditeur: Nature

Understanding the factors that shape patterns of nucleotide diversity in the house mouse genome

Auteurs: Tom R. Booker; Peter D. Keightley
Publié dans: Booker , T R & Keightley , P D 2018 , ' Understanding the factors that shape patterns of nucleotide diversity in the house mouse genome ' , Molecular Biology and Evolution . https://doi.org/10.1093/molbev/msy188, Numéro 1, 2018, ISSN 1537-1719
Éditeur: OuP
DOI: 10.1101/275610

Patterns of population structure and complex haplotype sharing among field isolates of the green alga Chlamydomonas reinhardtii

Auteurs: Rory J. Craig, Katharina B. Böndel, Kazuharu Arakawa, Takashi Nakada, Takuro Ito, Graham Bell, Nick Colegrave, Peter D. Keightley, Rob W. Ness
Publié dans: Molecular Ecology, Numéro 28/17, 2019, Page(s) 3977-3993, ISSN 0962-1083
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/mec.15193

Inferring the Probability of the Derived versus the Ancestral Allelic State at a Polymorphic Site

Auteurs: Peter D. Keightley, Benjamin C. Jackson
Publié dans: Genetics, 2018, Page(s) genetics.301120.2018, ISSN 0016-6731
Éditeur: Genetics Society of America
DOI: 10.1534/genetics.118.301120

The Recombination Landscape in Wild House Mice Inferred Using Population Genomic Data

Auteurs: Tom R. Booker, Rob W. Ness, Peter D. Keightley
Publié dans: Genetics, Numéro 207/1, 2017, Page(s) 297-309, ISSN 0016-6731
Éditeur: Genetics Society of America
DOI: 10.1534/genetics.117.300063

Detecting positive selection in the genome

Auteurs: Tom R. Booker, Benjamin C. Jackson, Peter D. Keightley
Publié dans: BMC Biology, Numéro 15/1, 2017, ISSN 1741-7007
Éditeur: BioMed Central
DOI: 10.1186/s12915-017-0434-y

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